A2X6X1 (CDKG1_ORYSI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cyclin-dependent kinase G-1
Short name=CDKG;1
EC=2.7.11.22
EC=2.7.11.23

Gene names

Name:	CDKG-1
ORF Names:	OsI_007814

Organism

Oryza sativa subsp. indica (Rice)

Taxonomic identifier

39946 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	693 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.
Sequence similarities	Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. Contains 1 protein kinase domain.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase Transferase
PTM	Phosphoprotein
Gene Ontology (GO)
Biological_process	cell cycle Inferred from electronic annotation. Source: GOC
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW RNA polymerase II carboxy-terminal domain kinase activity Inferred from electronic annotation. Source: EC cyclin-dependent protein serine/threonine kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 693	693	Cyclin-dependent kinase G-1		PRO_0000296111
Regions
	Domain	349 – 640	292	Protein kinase
	Nucleotide binding	355 – 363	9	ATP By similarity
Sites
	Active site	473	1	Proton acceptor By similarity
	Binding site	378	1	ATP By similarity
Amino acid modifications
	Modified residue	359	1	Phosphothreonine By similarity
	Modified residue	360	1	Phosphotyrosine By similarity
	Modified residue	500	1	Phosphoserine By similarity
	Modified residue	506	1	Phosphothreonine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A2X6X1 [UniParc]. Last modified March 20, 2007. Version 1. Checksum: 77BBFE0F2AF3C5C1	FASTA	693	78,849
	10 20 30 40 50 60 MAAGSHGGYR GYEVAREREH DVGVSRRSKE HYHHRHPSRH RDSERRRDGG RSGGRELSNG 70 80 90 100 110 120 YSHRRDSPRP PPRRRPSEGR TEDREPGEVS GGSGSERSGE RPMKTREPRE NGVTRVSKEE 130 140 150 160 170 180 AKMSPSKKRK QSPVIWDRNG SQRQARDPVR GIREVDAVVA EIIMHQSHSL PVMSSLSSIG 190 200 210 220 230 240 DGHSPMILDV SVDKVQEYEK NRIVDEEEEG YPTMRNILTS RWADAGDEEE NVFVPKKKKS 250 260 270 280 290 300 VSPVDSIERG STKKVTSPES GEVLVYNSVR SSSRSSDSGV LQGSANRDLE VEKGDNIDVE 310 320 330 340 350 360 KAADDDYPAG HLLDSDFEGE DCRSETPECT RSPRRCINML QGCRSVDEFE RLNTINEGTY 370 380 390 400 410 420 GVVFRVRDKR TGEIVALKKV KMEKEREGFP LTSLREMNIL LSFHHPSIVE VKEVVVGSND 430 440 450 460 470 480 RDIFMVMEYM EHDLKGVMET MKQPYSQSEV KCLMLQLLEG VKYLHDNWVL HRDLKTSNLL 490 500 510 520 530 540 LNNRGELKIC DFGLSRQYGS PLKPYTQLVV TLWYRAPELL LGAKDYSTAI DMWSLGCIMG 550 560 570 580 590 600 ELLSKGPLFN GKSEIDQLDK IFRTLGTPDE NIWPGYSKLP GATVKFGKQT HNRLRDKFRA 610 620 630 640 650 660 VSFTGGPMLS EAGFDLLNRL LTYDPEKRIS AEDALNHEWF RELPLPRSKD FMPTFPALNE 670 680 690 QDRRFKKHMK SPDPLEEQWM KEQGNNGDRG LFG

References

[1]

"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. 93-11.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CM000127 Genomic DNA. Translation: EAY86581.1.
3D structure databases
ProteinModelPortal	A2X6X1.
ModBase	Search...
Protein-protein interaction databases
STRING	39947.LOC_Os02g39010.1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
Gramene	A2X6X1.
Phylogenomic databases
eggNOG	COG0515.
Gene expression databases
ArrayExpress	A2X6X1.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR002290. Ser/Thr_dual-sp_kinase_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. False negative. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CDKG1_ORYSI

Accession

Primary (citable) accession number: A2X6X1

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 24, 2007
Last sequence update:	March 20, 2007
Last modified:	May 1, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program