SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A2X2G3

- PP2A3_ORYSI

UniProt

A2X2G3 - PP2A3_ORYSI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Serine/threonine-protein phosphatase PP2A-3 catalytic subunit
Gene
PP2A3, OsI_006256
Organism
Oryza sativa subsp. indica (Rice)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi55 – 551Manganese 1 By similarity
Metal bindingi57 – 571Manganese 1 By similarity
Metal bindingi83 – 831Manganese 1 By similarity
Metal bindingi83 – 831Manganese 2 By similarity
Metal bindingi115 – 1151Manganese 2 By similarity
Active sitei116 – 1161Proton donor By similarity
Metal bindingi165 – 1651Manganese 2 By similarity
Metal bindingi239 – 2391Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW

GO - Biological processi

  1. cellular protein localization Source: EnsemblPlants/Gramene
  2. chloroplast avoidance movement Source: EnsemblPlants/Gramene
  3. protein dephosphorylation Source: EnsemblPlants/Gramene
  4. regulation of auxin polar transport Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP2A-3 catalytic subunit (EC:3.1.3.16)
Gene namesi
Name:PP2A3
ORF Names:OsI_006256
OrganismiOryza sativa subsp. indica (Rice)
Taxonomic identifieri39946 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Organism-specific databases

GrameneiA2X2G3.

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytosol Source: EnsemblPlants/Gramene
  2. nucleus Source: EnsemblPlants/Gramene
  3. plasma membrane Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 307307Serine/threonine-protein phosphatase PP2A-3 catalytic subunit
PRO_0000301657Add
BLAST

Proteomic databases

PRIDEiA2X2G3.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os02g12580.1.

Structurei

3D structure databases

ProteinModelPortaliA2X2G3.
SMRiA2X2G3. Positions 7-307.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0639.
HOGENOMiHOG000172696.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2X2G3-1 [UniParc]FASTAAdd to Basket

« Hide

MPSSHGDLDR QIAQLRECKH LAEGEVRALC EQAKAILMEE WNVQPVRCPV    50
TVCGDIHGQF YDLIELFRIG GEAPDTNYLF MGDYVDRGYY SVETVSLLVA 100
LKVRYRDRIT ILRGNHESRQ ITQVYGFYDE CLRKYGNANV WKYFTDLFDY 150
LPLTALIENQ VFCLHGGLSP SLDTLDNIRA LDRIQEVPHE GPMCDLLWSD 200
PDDRCGWGIS PRGAGYTFGQ DIAQQFNHTN GLSLISRAHQ LVMEGFNWCQ 250
DKNVVTVFSA PNYCYRCGNM AAILEIGENM DQNFLQFDPA PRQIEPDTTR 300
KTPDYFL 307
Length:307
Mass (Da):35,145
Last modified:September 11, 2007 - v2
Checksum:i97143563695D0DD6
GO

Sequence cautioni

The sequence CM000127 differs from that shown. Reason: Frameshift at positions 39 and 52.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti60 – 601F → P in CM000127. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF159061 Genomic DNA. Translation: AAD41126.1.
CM000127 Genomic DNA. No translation available.
CT832108 mRNA. No translation available.
UniGeneiOs.10337.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF159061 Genomic DNA. Translation: AAD41126.1 .
CM000127 Genomic DNA. No translation available.
CT832108 mRNA. No translation available.
UniGenei Os.10337.

3D structure databases

ProteinModelPortali A2X2G3.
SMRi A2X2G3. Positions 7-307.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 39947.LOC_Os02g12580.1.

Proteomic databases

PRIDEi A2X2G3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Gramenei A2X2G3.

Phylogenomic databases

eggNOGi COG0639.
HOGENOMi HOG000172696.

Family and domain databases

Gene3Di 3.60.21.10. 1 hit.
InterProi IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view ]
Pfami PF00149. Metallophos. 1 hit.
[Graphical view ]
PRINTSi PR00114. STPHPHTASE.
SMARTi SM00156. PP2Ac. 1 hit.
[Graphical view ]
SUPFAMi SSF56300. SSF56300. 1 hit.
PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning and characterization of protein phosphatase 2A catalytic subunit genes from Oryza sativa."
    Yu R.M.K., Kong R.Y.C.
    Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. IR36.
  2. "The genomes of Oryza sativa: a history of duplications."
    Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
    , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
    PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. 93-11.
  3. "A collection of 10,096 indica rice full-length cDNAs reveals highly expressed sequence divergence between Oryza sativa indica and japonica subspecies."
    Liu X., Lu T., Yu S., Li Y., Huang Y., Huang T., Zhang L., Zhu J., Zhao Q., Fan D., Mu J., Shangguan Y., Feng Q., Guan J., Ying K., Zhang Y., Lin Z., Sun Z.
    , Qian Q., Lu Y., Han B.
    Plant Mol. Biol. 65:403-415(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Guang-Lu-Ai No.4.

Entry informationi

Entry nameiPP2A3_ORYSI
AccessioniPrimary (citable) accession number: A2X2G3
Secondary accession number(s): Q6Z6L8, Q6Z6L9, Q9XGT7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 11, 2007
Last modified: June 11, 2014
This is version 43 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi