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A2X2G3 (PP2A3_ORYSI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein phosphatase PP2A-3 catalytic subunit

EC=3.1.3.16
Gene names
Name:PP2A3
ORF Names:OsI_006256
OrganismOryza sativa subsp. indica (Rice)
Taxonomic identifier39946 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 manganese ions per subunit By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the PPP phosphatase family. PP-2A subfamily.

Sequence caution

The sequence CM000127 differs from that shown. Reason: Frameshift at positions 39 and 52.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandManganese
Metal-binding
   Molecular functionHydrolase
Protein phosphatase
Gene Ontology (GO)
   Biological_processcellular protein localization

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

chloroplast avoidance movement

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

protein dephosphorylation

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

regulation of auxin polar transport

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Cellular_componentcytosol

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

nucleus

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

plasma membrane

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 307307Serine/threonine-protein phosphatase PP2A-3 catalytic subunit
PRO_0000301657

Sites

Active site1161Proton donor By similarity
Metal binding551Manganese 1 By similarity
Metal binding571Manganese 1 By similarity
Metal binding831Manganese 1 By similarity
Metal binding831Manganese 2 By similarity
Metal binding1151Manganese 2 By similarity
Metal binding1651Manganese 2 By similarity
Metal binding2391Manganese 2 By similarity

Experimental info

Sequence conflict601F → P in CM000127. Ref.2

Sequences

Sequence LengthMass (Da)Tools
A2X2G3 [UniParc].

Last modified September 11, 2007. Version 2.
Checksum: 97143563695D0DD6

FASTA30735,145
        10         20         30         40         50         60 
MPSSHGDLDR QIAQLRECKH LAEGEVRALC EQAKAILMEE WNVQPVRCPV TVCGDIHGQF 

        70         80         90        100        110        120 
YDLIELFRIG GEAPDTNYLF MGDYVDRGYY SVETVSLLVA LKVRYRDRIT ILRGNHESRQ 

       130        140        150        160        170        180 
ITQVYGFYDE CLRKYGNANV WKYFTDLFDY LPLTALIENQ VFCLHGGLSP SLDTLDNIRA 

       190        200        210        220        230        240 
LDRIQEVPHE GPMCDLLWSD PDDRCGWGIS PRGAGYTFGQ DIAQQFNHTN GLSLISRAHQ 

       250        260        270        280        290        300 
LVMEGFNWCQ DKNVVTVFSA PNYCYRCGNM AAILEIGENM DQNFLQFDPA PRQIEPDTTR 


KTPDYFL 

« Hide

References

« Hide 'large scale' references
[1]"Molecular cloning and characterization of protein phosphatase 2A catalytic subunit genes from Oryza sativa."
Yu R.M.K., Kong R.Y.C.
Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. IR36.
[2]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. 93-11.
[3]"A collection of 10,096 indica rice full-length cDNAs reveals highly expressed sequence divergence between Oryza sativa indica and japonica subspecies."
Liu X., Lu T., Yu S., Li Y., Huang Y., Huang T., Zhang L., Zhu J., Zhao Q., Fan D., Mu J., Shangguan Y., Feng Q., Guan J., Ying K., Zhang Y., Lin Z., Sun Z. expand/collapse author list , Qian Q., Lu Y., Han B.
Plant Mol. Biol. 65:403-415(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Guang-Lu-Ai No.4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF159061 Genomic DNA. Translation: AAD41126.1.
CM000127 Genomic DNA. No translation available.
CT832108 mRNA. No translation available.
UniGeneOs.10337.

3D structure databases

ProteinModelPortalA2X2G3.
SMRA2X2G3. Positions 7-307.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING39947.LOC_Os02g12580.1.

Proteomic databases

PRIDEA2X2G3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GrameneA2X2G3.

Phylogenomic databases

eggNOGCOG0639.
HOGENOMHOG000172696.

Family and domain databases

Gene3D3.60.21.10. 1 hit.
InterProIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSPR00114. STPHPHTASE.
SMARTSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMSSF56300. SSF56300. 1 hit.
PROSITEPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePP2A3_ORYSI
AccessionPrimary (citable) accession number: A2X2G3
Secondary accession number(s): Q6Z6L8, Q6Z6L9, Q9XGT7
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 11, 2007
Last modified: June 11, 2014
This is version 43 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families