Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable histone H2A.5

Gene

OsI_002060

more
Organism
Oryza sativa subsp. indica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

GO - Molecular functioni

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable histone H2A.5
Gene namesi
ORF Names:OsI_002060
AND
ORF Names:OsI_010711
OrganismiOryza sativa subsp. indica (Rice)
Taxonomic identifieri39946 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000007015 Componentsi: Chromosome 1, Chromosome 3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleosome core, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002961231 – 159Probable histone H2A.5Add BLAST159

Proteomic databases

PRIDEiA2WQG7.

Interactioni

Subunit structurei

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

GO - Molecular functioni

Protein-protein interaction databases

STRINGi39946.BGIOSGA010990-PA.

Structurei

3D structure databases

ProteinModelPortaliA2WQG7.
SMRiA2WQG7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi147 – 150SPKK motif 14
Motifi155 – 158SPKK motif 24

Domaini

Sequence similaritiesi

Belongs to the histone H2A family.Curated

Phylogenomic databases

eggNOGiKOG1756. Eukaryota.
COG5262. LUCA.
HOGENOMiHOG000234652.
OMAiANAARHN.
OrthoDBiEOG09360WU4.

Family and domain databases

InterProiView protein in InterPro
IPR009072. Histone-fold.
IPR002119. Histone_H2A.
IPR007125. Histone_H2A/H2B/H3.
IPR032454. Histone_H2A_C.
IPR032458. Histone_H2A_CS.
PfamiView protein in Pfam
PF00125. Histone. 1 hit.
PF16211. Histone_H2A_C. 1 hit.
PRINTSiPR00620. HISTONEH2A.
SMARTiView protein in SMART
SM00414. H2A. 1 hit.
SUPFAMiSSF47113. SSF47113. 1 hit.
PROSITEiView protein in PROSITE
PS00046. HISTONE_H2A. 1 hit.

Sequencei

Sequence statusi: Complete.

A2WQG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAAGAGAGG KLKKGAAGRK AGGPRKKAVS RSVKAGLQFP VGRIGRYLKK
60 70 80 90 100
GRYAQRIGTG APVYLAAVLE YLAAEVLELA GNAARDNKKN RIIPRHVLLA
110 120 130 140 150
IRNDEELGKL LAGVTIAHGG VLPNINPVLL PKKTAEKAAA AGKEAKSPKK

AAGKSPKKA
Length:159
Mass (Da):16,401
Last modified:March 20, 2007 - v1
Checksum:iDF8301D4C45A7697
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000126 Genomic DNA. Translation: EAY74213.1.
CM000128 Genomic DNA. Translation: EAY89478.1.

Genome annotation databases

EnsemblPlantsiBGIOSGA003601-TA; BGIOSGA003601-PA; BGIOSGA003601.
BGIOSGA010990-TA; BGIOSGA010990-PA; BGIOSGA010990.
GrameneiBGIOSGA003601-TA; BGIOSGA003601-PA; BGIOSGA003601.
BGIOSGA010990-TA; BGIOSGA010990-PA; BGIOSGA010990.

Similar proteinsi

Entry informationi

Entry nameiH2A5_ORYSI
AccessioniPrimary (citable) accession number: A2WQG7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: March 20, 2007
Last modified: August 30, 2017
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families