A2VN25 (A2VN25_MYCTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Bifunctional mta/sah nucleosidase mtn : 5-methylthioadenosine nucleosidase + S-adenosylhomocysteine nucleosidase EMBL EAY61556.1

Gene names

ORF Names:

TBCG_00092 EMBL EAY61556.1

Organism

Mycobacterium tuberculosis C EMBL EAY61556.1

Taxonomic identifier

348776 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

S-adenosyl-L-homocysteine + H2O = S-(5-deoxy-D-ribos-5-yl)-L-homocysteine + adenine. SAAS SAAS010049 S-methyl-5'-thioadenosine + H2O = S-methyl-5-thio-D-ribose + adenine. SAAS SAAS010049

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Methionine biosynthesis SAAS SAAS010049
Molecular function	Hydrolase SAAS SAAS010049
Gene Ontology (GO)
Biological process	L-methionine salvage from methylthioadenosine Inferred from electronic annotation. Source: InterPro nucleoside catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	adenosylhomocysteine nucleosidase activity Inferred from electronic annotation. Source: InterPro methylthioadenosine nucleosidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2VN25 [UniParc]. Last modified March 20, 2007. Version 1. Checksum: EA80AA80B2BFEE79	FASTA	255	27,340
	10 20 30 40 50 60 MAVTVGVICA IPQELAYLRG VLVDAKRQQV AQILFDSGQL DAHRVVLAAA GMGKVNTGLT 70 80 90 100 110 120 ATLLADRFGC RTIVFTGVAG GLDPELCIGD IVIADRVVQH DFGLLTDERL RPYQPGHIPF 130 140 150 160 170 180 IEPTERLGYP VDPAVIDRVK HRLDGFTLAP LSTAAGGGGR QPRIYYGTIL TGDQYLHCER 190 200 210 220 230 240 TRNRLHHELG GMAVEMEGGA VAQICASFDI PWLVIRALSD LAGADSGVDF NRFVGEVAAS 250 SARVLLRLLP VLTAC

References

[1]

"The Genome Sequence of Mycobacterium tuberculosis (strain C)." The Broad Institute Genome Sequencing Platform Birren B., Lander E., Galagan J., Devon K., Nusbaum C., Borowsky M.L., Jaffe D., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E., Brockman W., Rounsley S., Young S., LaButti K., Pushparaj V. , DeCaprio D., Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C., Kodira C., Zeng Q., Yandava C., Oleary S., Alvarado L., Murray M., Kreiswirth B. Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C EMBL EAY61556.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH482374 Genomic DNA. Translation: EAY61556.1.
3D structure databases
ProteinModelPortal	A2VN25.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	26051584. VBIMycTub57268_3361.
Phylogenomic databases
OMA	NVFWINT.
Family and domain databases
InterPro	IPR010049. MTA_SAH_Nsdase. IPR018017. Nucleoside_phosphorylase. IPR000845. Nucleoside_phosphorylase_d. [Graphical view]
PANTHER	PTHR21234. PNP_UDP. 1 hit. PTHR21234:SF6. PTHR21234:SF6. 1 hit.
Pfam	PF01048. PNP_UDP_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A2VN25_MYCTU

Accession

Primary (citable) accession number: A2VN25

Entry history

Integrated into UniProtKB/TrEMBL:	March 20, 2007
Last sequence update:	March 20, 2007
Last modified:	December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)