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A2VGA9 (A2VGA9_MYCTU) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylformylglycinamidine cyclo-ligase RuleBase RU004370
EC=6.3.3.1 RuleBase RU004370
Gene names
ORF Names:TBCG_00799 EMBL EAY59190.1
OrganismMycobacterium tuberculosis C EMBL EAY59190.1
Taxonomic identifier348776 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length364 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. RuleBase RU004370 SAAS SAAS004733

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. RuleBase RU004371 SAAS SAAS004733

Subcellular location

Cytoplasm By similarity SAAS SAAS004733.

Sequence similarities

Belongs to the AIR synthase family. RuleBase RU004370

Sequences

Sequence LengthMass (Da)Tools
A2VGA9 [UniParc].

Last modified March 20, 2007. Version 1.
Checksum: 9ECF162DE6C59A92

FASTA36438,393
        10         20         30         40         50         60 
MTDLAKGPGK DPGSRGITYA SAGVDIEAGD RAIDLFKPLA SKATRPEVRG GLGGFAGLFT 

        70         80         90        100        110        120 
LRGDYREPVL AASSDGVGTK LAIAQAMDKH DTVGLDLVAM VVDDLVVCGA EPLFLLDYIA 

       130        140        150        160        170        180 
VGRIVPERLS AIVAGIADGC MRAGCALLGG ETAEHPGLIE PDHYDISATG VGVVEADNVL 

       190        200        210        220        230        240 
GPDRVKPGDV IIAMGSSGLH SNGYSLVRKV LLEIDRMNLA GHVEEFGRTL GEELLEPTRI 

       250        260        270        280        290        300 
YAKDCLALAA ETRVRTFCHV TGGGLAGNLQ RVIPHGLIAE VDRGTWTPAP VFTMIAQRGR 

       310        320        330        340        350        360 
VRRTEMEKTF NMGVGMIAVV APEDTTRALA VLTARHLDCW VLGTVCKGGK QGPRAKLVGQ 


HPRF

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CH482373 Genomic DNA. Translation: EAY59190.1.

3D structure databases

ProteinModelPortalA2VGA9.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

PATRIC26045310. VBIMycTub57268_0612.

Phylogenomic databases

OMAPENIPRV.

Family and domain databases

InterProIPR000728. AIR_synth.
IPR010918. AIR_synth_C.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMSSF56042. AIR_synth_C. 1 hit.
SSF55326. PurM_N-like. 1 hit.
TIGRFAMsTIGR00878. PurM. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA2VGA9_MYCTU
AccessionPrimary (citable) accession number: A2VGA9
Entry history
Integrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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