A2VED2 (A2VED2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Augmented in rheumatoid arthritis 17 EMBL FAA00322.1

Gene names

Name:

AURA17 EMBL FAA00322.1

Organism

Homo sapiens (Human) EMBL FAA00322.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	870 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Miscellaneous

The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.

Ontologies

Keywords
Domain	Leucine-rich repeat SAAS SAAS003591 Repeat SAAS SAAS003591
Gene Ontology (GO)
None. [Check GOA]

Sequences

	Sequence		Length	Mass (Da)
	A2VED2 [UniParc]. Last modified March 20, 2007. Version 1. Checksum: 3F8387DBABE294A5	FASTA	870	97,591
	10 20 30 40 50 60 MLSMLMHSSS KEVFQASANA LSTLLEQNVN FRKILLSKGI HLNVLELMQK HIHSPEVAES 70 80 90 100 110 120 GCKMLNHLFE GSNTSLDIMA AVVPKILTVM KRHETSLPVQ LEALRAILHF IVPGMPEESR 130 140 150 160 170 180 EDTEFHHKLN MVKKQCFKND IHKLVLAALN RFIGNPGIQK CGLKVISSIV HFPDALEMLS 190 200 210 220 230 240 LEGAMDSVLH TLQMYPDDQE IQCLGLSLIG YLITKKNVFI GTGHLLAKIL VSSLYRFKDV 250 260 270 280 290 300 AEIQTKGFQT ILAILKLSAS FSKLLVHHSF DLVIFHQMSS NIMEQKDQQF LNLCCKCFAK 310 320 330 340 350 360 VAMDDYLKNV MLERACDQNN SIMVECLLLL GADANQAKEG SSLICQVCEK ESSPKLVELL 370 380 390 400 410 420 LNSGSREQDV RKALTISIGK GDSQIISLLL RRLALDVANN SICLGGFCIG KVEPSWLGPL 430 440 450 460 470 480 FPDKTSNLRK QTNIASTLAR MVIRYQMKSA VEEGTASGSD GNFSEDVLSK FDEWTFIPDS 490 500 510 520 530 540 SMDSVFAQSD DLDSEGSEGS FLVKKKSNSI SVGEFYRDAV LQRCSPNLQR HSNSLGPIFD 550 560 570 580 590 600 HEDLLKRKRK ILSSDDSLRS SKLQSHMRHS DSISSLASER EYITSLDLSA NELRDIDALS 610 620 630 640 650 660 QKCCISVHLE HLEKLELHQN ALTSFPQQLC ETLKSLTHLD LHSNKFTSFP SYLLKMSCIA 670 680 690 700 710 720 NLDVSRNDIG PSVVLDPTVK CPTLKQFNLS YNQLSFVPEN LTDVVEKLEQ LILEGNKISG 730 740 750 760 770 780 ICSPLRLKEL KILNLSKNHI SSLSENFLEA CPKVESFSAR MNFLAAMPFL PPSMTILKLS 790 800 810 820 830 840 QNKFSCIPEA ILNLPHLRSL DMSSNDIQYL PGPAHWKSLN LRELLFSHNQ ISILDLSEKA 850 860 870 YLWSRVEKLH LSHNKLKEVR RLLPLKKYTL

References

[1]	"Isolation and expression profiling of genes upregulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients." Nakamura N., Shimaoka Y., Tougan T., Onda H., Okuzaki D., Zhao H., Fujimori A., Yabuta N., Nagamori I., Tanigawa A., Sato J., Oda T., Hayashida K., Suzuki R., Yukioka M., Nojima H., Ochi T. DNA Res. 13:169-183(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Nojima H., Tougan T. Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BR000408 mRNA. Translation: FAA00322.1.
IPI	IPI00794835.
UniGene	Hs.187636.
3D structure databases
ProteinModelPortal	A2VED2.
SMR	A2VED2. Positions 308-406, 579-859.
ModBase	Search...
Protein-protein interaction databases
STRING	A2VED2.
Proteomic databases
PRIDE	A2VED2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOGENOM	HOG000237366.
HOVERGEN	HBG080795.
OrthoDB	EOG4X97G8.
Gene expression databases
ArrayExpress	A2VED2.
Bgee	A2VED2.
Family and domain databases
Gene3D	1.25.10.10. 1 hit. 1.25.40.20. 1 hit.
InterPro	IPR020683. Ankyrin_rpt-contain_dom. IPR011989. ARM-like. IPR016024. ARM-type_fold. IPR001611. Leu-rich_rpt. IPR003591. Leu-rich_rpt_typical-subtyp. [Graphical view]
Pfam	PF00560. LRR_1. 1 hit. [Graphical view]
SMART	SM00369. LRR_TYP. 1 hit. [Graphical view]
SUPFAM	SSF48371. ARM-type_fold. 1 hit.
PROSITE	PS51450. LRR. 10 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	35461412.

Entry information

Entry name

A2VED2_HUMAN

Accession

Primary (citable) accession number: A2VED2

Entry history

Integrated into UniProtKB/TrEMBL:	March 20, 2007
Last sequence update:	March 20, 2007
Last modified:	April 3, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.