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A2VED2

- A2VED2_HUMAN

UniProt

A2VED2 - A2VED2_HUMAN

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Protein
Submitted name:

Augmented in rheumatoid arthritis 17

Gene

AURA17

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Augmented in rheumatoid arthritis 17Imported
Gene namesi
Name:AURA17Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiA2VED2.

Expressioni

Gene expression databases

BgeeiA2VED2.
ExpressionAtlasiA2VED2. baseline and differential.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliA2VED2.
SMRiA2VED2. Positions 308-406, 579-859.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Leucine-rich repeatSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

HOGENOMiHOG000237366.
HOVERGENiHBG080795.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
1.25.40.20. 1 hit.
InterProiIPR020683. Ankyrin_rpt-contain_dom.
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view]
PfamiPF00560. LRR_1. 1 hit.
PF13855. LRR_8. 2 hits.
[Graphical view]
SMARTiSM00369. LRR_TYP. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS51450. LRR. 10 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2VED2-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MLSMLMHSSS KEVFQASANA LSTLLEQNVN FRKILLSKGI HLNVLELMQK
60 70 80 90 100
HIHSPEVAES GCKMLNHLFE GSNTSLDIMA AVVPKILTVM KRHETSLPVQ
110 120 130 140 150
LEALRAILHF IVPGMPEESR EDTEFHHKLN MVKKQCFKND IHKLVLAALN
160 170 180 190 200
RFIGNPGIQK CGLKVISSIV HFPDALEMLS LEGAMDSVLH TLQMYPDDQE
210 220 230 240 250
IQCLGLSLIG YLITKKNVFI GTGHLLAKIL VSSLYRFKDV AEIQTKGFQT
260 270 280 290 300
ILAILKLSAS FSKLLVHHSF DLVIFHQMSS NIMEQKDQQF LNLCCKCFAK
310 320 330 340 350
VAMDDYLKNV MLERACDQNN SIMVECLLLL GADANQAKEG SSLICQVCEK
360 370 380 390 400
ESSPKLVELL LNSGSREQDV RKALTISIGK GDSQIISLLL RRLALDVANN
410 420 430 440 450
SICLGGFCIG KVEPSWLGPL FPDKTSNLRK QTNIASTLAR MVIRYQMKSA
460 470 480 490 500
VEEGTASGSD GNFSEDVLSK FDEWTFIPDS SMDSVFAQSD DLDSEGSEGS
510 520 530 540 550
FLVKKKSNSI SVGEFYRDAV LQRCSPNLQR HSNSLGPIFD HEDLLKRKRK
560 570 580 590 600
ILSSDDSLRS SKLQSHMRHS DSISSLASER EYITSLDLSA NELRDIDALS
610 620 630 640 650
QKCCISVHLE HLEKLELHQN ALTSFPQQLC ETLKSLTHLD LHSNKFTSFP
660 670 680 690 700
SYLLKMSCIA NLDVSRNDIG PSVVLDPTVK CPTLKQFNLS YNQLSFVPEN
710 720 730 740 750
LTDVVEKLEQ LILEGNKISG ICSPLRLKEL KILNLSKNHI SSLSENFLEA
760 770 780 790 800
CPKVESFSAR MNFLAAMPFL PPSMTILKLS QNKFSCIPEA ILNLPHLRSL
810 820 830 840 850
DMSSNDIQYL PGPAHWKSLN LRELLFSHNQ ISILDLSEKA YLWSRVEKLH
860 870
LSHNKLKEVR RLLPLKKYTL
Length:870
Mass (Da):97,591
Last modified:March 20, 2007 - v1
Checksum:i3F8387DBABE294A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BR000408 mRNA. Translation: FAA00322.1.
UniGeneiHs.187636.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BR000408 mRNA. Translation: FAA00322.1 .
UniGenei Hs.187636.

3D structure databases

ProteinModelPortali A2VED2.
SMRi A2VED2. Positions 308-406, 579-859.
ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi A2VED2.

Proteomic databases

PRIDEi A2VED2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOGENOMi HOG000237366.
HOVERGENi HBG080795.

Miscellaneous databases

ChiTaRSi LRRK2. human.
NextBioi 35461412.

Gene expression databases

Bgeei A2VED2.
ExpressionAtlasi A2VED2. baseline and differential.

Family and domain databases

Gene3Di 1.25.10.10. 1 hit.
1.25.40.20. 1 hit.
InterProi IPR020683. Ankyrin_rpt-contain_dom.
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view ]
Pfami PF00560. LRR_1. 1 hit.
PF13855. LRR_8. 2 hits.
[Graphical view ]
SMARTi SM00369. LRR_TYP. 1 hit.
[Graphical view ]
SUPFAMi SSF48371. SSF48371. 1 hit.
PROSITEi PS51450. LRR. 10 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Isolation and expression profiling of genes upregulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients."
    Nakamura N., Shimaoka Y., Tougan T., Onda H., Okuzaki D., Zhao H., Fujimori A., Yabuta N., Nagamori I., Tanigawa A., Sato J., Oda T., Hayashida K., Suzuki R., Yukioka M., Nojima H., Ochi T.
    DNA Res. 13:169-183(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Nojima H., Tougan T.
    Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiA2VED2_HUMAN
AccessioniPrimary (citable) accession number: A2VED2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 20, 2007
Last sequence update: March 20, 2007
Last modified: November 26, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Miscellaneous

The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.

External Data

Dasty 3