TMSB4X

Functionⁱ

GO - Molecular functionⁱ

actin monomer binding Source: InterPro

GO - Biological processⁱ

actin filament organization Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Thymosin beta 4, X-linkedImported Submitted name: Thymosin, beta 4, X-linked, isoform CRA_aImported Submitted name: cDNA, FLJ92006, Homo sapiens thymosin, beta 4, X chromosome (TMSB4X), mRNAImported
Gene namesⁱ	Name:TMSB4XImported ORF Names:hCG_1646598Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Pathology & Biotechⁱ

Organism-specific databases

PharmGKBⁱ	PA36581.

PharmGKBⁱ

PA36581.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000205542.
ExpressionAtlasⁱ	A2VCK8. baseline and differential.

Interactionⁱ

GO - Molecular functionⁱ

actin monomer binding Source: InterPro

Complete GO annotation...

Protein-protein interaction databases

ELMⁱ	A2VCK8.

ELMⁱ

A2VCK8.

Structureⁱ

3D structure databases

SMRⁱ	A2VCK8.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Phylogenomic databases

eggNOGⁱ	KOG4794. Eukaryota. ENOG410Y3I4. LUCA.
HOVERGENⁱ	HBG012534.
KEGG Orthology (KO) More...KOⁱ	K05764.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G1AVI.

Family and domain databases

InterProⁱ	View protein in InterPro IPR001152. Beta-thymosin.
PANTHERⁱ	PTHR12021. PTHR12021. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01290. Thymosin. 1 hit.
PIRSFⁱ	PIRSF001828. Thymosin_beta. 1 hit.
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD005116. Thymosin_b4. 1 hit.
SMARTⁱ	View protein in SMART SM00152. THY. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00500. THYMOSIN_B4. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

A2VCK8-1 [UniParc]FASTA Add to basket

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        10         20         30         40 
MSDKPDMAEI EKFDKSKLKK TETQEKNPLP SKETIEQEKQ AGES

Length:44

Mass (Da):5,053

Last modified:March 20, 2007 - v1

Checksum:ⁱ440C6158482DAAD0

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC101790 mRNA. Translation: AAI01791.1. BC101792 mRNA. Translation: AAI01793.1. BC104464 mRNA. Translation: AAI04465.1. BC104465 mRNA. Translation: AAI04466.1. BC128102 mRNA. Translation: AAI28103.1. BC128103 mRNA. Translation: AAI28104.1. BC139925 mRNA. Translation: AAI39926.1. BC141975 mRNA. Translation: AAI41976.1. BC141976 mRNA. Translation: AAI41977.1. BC151215 mRNA. Translation: AAI51216.1. AK311747 mRNA. Translation: BAG34690.1. CH471074 Genomic DNA. Translation: EAW98810.1. CH471074 Genomic DNA. Translation: EAW98811.1. CH471074 Genomic DNA. Translation: EAW98812.1. CH471074 Genomic DNA. Translation: EAW98814.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_066932.1. NM_021109.3.
UniGeneⁱ	Hs.437277. Hs.703237.

Genome annotation databases

GeneIDⁱ	7114.
KEGGⁱ	hsa:7114.

Similar proteinsⁱ

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
A2VCK8	P62328 P62326 Q6S9C5 P62327 Q95274 Q5R7H8 P62329 A0A1U7U3V9 F7HV51 H2PYT4 +42	Homo sapiens (Human) Bos taurus (Bovine) Chinchilla lanigera (Long-tailed chinchilla) (Chinchilla villidera) Equus caballus (Horse) Sus scrofa (Pig) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Rattus norvegicus (Rat) Tarsius syrichta (Philippine tarsier) Callithrix jacchus (White-tufted-ear marmoset) Pan troglodytes (Chimpanzee) And more	44	UniRef100_P62328	Cluster: Thymosin beta-4	53

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
A2VCK8	P62328 P62326 Q6S9C5 P62327 Q95274 Q5R7H8 P62329 A0A1U7U3V9 F7HV51 H2PYT4 +42	Homo sapiens (Human) Bos taurus (Bovine) Chinchilla lanigera (Long-tailed chinchilla) (Chinchilla villidera) Equus caballus (Horse) Sus scrofa (Pig) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Rattus norvegicus (Rat) Tarsius syrichta (Philippine tarsier) Callithrix jacchus (White-tufted-ear marmoset) Pan troglodytes (Chimpanzee) And more	44	UniRef90_P62328	Cluster: Thymosin beta-4	53

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
A2VCK8	P62328 P62326 Q6S9C5 P62327 Q95274 Q5R7H8 P62329 A0A1U7U3V9 F7HV51 H2PYT4 +42	Homo sapiens (Human) Bos taurus (Bovine) Chinchilla lanigera (Long-tailed chinchilla) (Chinchilla villidera) Equus caballus (Horse) Sus scrofa (Pig) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Rattus norvegicus (Rat) Tarsius syrichta (Philippine tarsier) Callithrix jacchus (White-tufted-ear marmoset) Pan troglodytes (Chimpanzee) And more	44	UniRef50_P62328	Cluster: Thymosin beta-4	53

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC101790 mRNA. Translation: AAI01791.1. BC101792 mRNA. Translation: AAI01793.1. BC104464 mRNA. Translation: AAI04465.1. BC104465 mRNA. Translation: AAI04466.1. BC128102 mRNA. Translation: AAI28103.1. BC128103 mRNA. Translation: AAI28104.1. BC139925 mRNA. Translation: AAI39926.1. BC141975 mRNA. Translation: AAI41976.1. BC141976 mRNA. Translation: AAI41977.1. BC151215 mRNA. Translation: AAI51216.1. AK311747 mRNA. Translation: BAG34690.1. CH471074 Genomic DNA. Translation: EAW98810.1. CH471074 Genomic DNA. Translation: EAW98811.1. CH471074 Genomic DNA. Translation: EAW98812.1. CH471074 Genomic DNA. Translation: EAW98814.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_066932.1. NM_021109.3.
UniGeneⁱ	Hs.437277. Hs.703237.

3D structure databases

SMRⁱ	A2VCK8.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

ELMⁱ	A2VCK8.

ELMⁱ

A2VCK8.

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	7114.
Structural Biology Knowledgebase	Search...

Genome annotation databases

GeneIDⁱ	7114.
KEGGⁱ	hsa:7114.

Organism-specific databases

CTDⁱ	7114.
PharmGKBⁱ	PA36581.

Phylogenomic databases

eggNOGⁱ	KOG4794. Eukaryota. ENOG410Y3I4. LUCA.
HOVERGENⁱ	HBG012534.
KEGG Orthology (KO) More...KOⁱ	K05764.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G1AVI.

Miscellaneous databases

ChiTaRSⁱ	TMSB4X. human.
GenomeRNAiⁱ	7114.

Gene expression databases

Bgeeⁱ	ENSG00000205542.
ExpressionAtlasⁱ	A2VCK8. baseline and differential.

Family and domain databases

InterProⁱ	View protein in InterPro IPR001152. Beta-thymosin.
PANTHERⁱ	PTHR12021. PTHR12021. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01290. Thymosin. 1 hit.
PIRSFⁱ	PIRSF001828. Thymosin_beta. 1 hit.
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD005116. Thymosin_b4. 1 hit.
SMARTⁱ	View protein in SMART SM00152. THY. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00500. THYMOSIN_B4. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	A2VCK8_HUMAN
Accessionⁱ	A2VCK8Primary (citable) accession number: A2VCK8
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	March 20, 2007
	Last sequence update:	March 20, 2007
	Last modified:	August 30, 2017
	This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

UniProtKB - A2VCK8 (A2VCK8_HUMAN)

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Thymosin beta 4, X-linked

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

Organism-specific databases

Expressionⁱ

Gene expression databases

Interactionⁱ

GO - Molecular functionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A2VCK8 (A2VCK8_HUMAN)

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Thymosin beta 4, X-linked

TMSB4X

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ