ID NSP6_ROTSH Reviewed; 92 AA. AC A2T3R0; DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot. DT 15-JAN-2008, sequence version 1. DT 14-DEC-2022, entry version 32. DE RecName: Full=Non-structural protein 6 {ECO:0000255|HAMAP-Rule:MF_04093}; DE Short=NSP6 {ECO:0000255|HAMAP-Rule:MF_04093}; OS Rotavirus A (isolate RVA/Monkey/South Africa/SA11-H96/1958/G3P5B[2]) (RV-A) OS (Simian Agent 11 (isolate SI/South Africa/H96/58)). OC Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes; OC Reovirales; Sedoreoviridae; Rotavirus; Rotavirus A. OX NCBI_TaxID=450149; OH NCBI_TaxID=60710; Chlorocebus pygerythrus (Vervet monkey) (Cercopithecus pygerythrus). RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC RNA]. RX PubMed=17059839; DOI=10.1016/j.virol.2006.09.024; RA Small C., Barro M., Brown T.L., Patton J.T.; RT "Genome heterogeneity of SA11 rotavirus due to reassortment with 'O' RT agent."; RL Virology 359:415-424(2007). CC -!- SUBUNIT: Interacts with NSP2 and NSP5. {ECO:0000255|HAMAP- CC Rule:MF_04093}. CC -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04093}. CC Host mitochondrion {ECO:0000255|HAMAP-Rule:MF_04093}. Note=Found in CC spherical cytoplasmic structures, called viral factories, that appear CC early after infection and are the site of viral replication and CC packaging. {ECO:0000255|HAMAP-Rule:MF_04093}. CC -!- SIMILARITY: Belongs to the rotavirus A NSP6 family. {ECO:0000255|HAMAP- CC Rule:MF_04093}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DQ838630; ABG75809.1; -; Genomic_RNA. DR RefSeq; YP_002302225.1; NC_011505.2. DR GeneID; 7011363; -. DR KEGG; vg:7011363; -. DR Proteomes; UP000001119; Genome. DR GO; GO:0033650; C:host cell mitochondrion; IEA:UniProtKB-SubCell. DR HAMAP; MF_04093; ROTA_NSP6; 1. DR InterPro; IPR006950; Rotavirus_NSP6. DR Pfam; PF04866; Rota_NS6; 1. PE 3: Inferred from homology; KW Host cytoplasm; Host mitochondrion; Reference proteome. FT CHAIN 1..92 FT /note="Non-structural protein 6" FT /id="PRO_0000369512" SQ SEQUENCE 92 AA; 11011 MW; 62378AF27FB00A93 CRC64; MNRLQQRQLF LENLLVGVNS TFHQMQKHSI NTCCRSLQRI LDHLILLQTI HSPVFRLDRM QLRQMQTLAC LWIHQHNHDL QVMSDAIKWI SP //