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A2STJ3

- RNP4_METLZ

UniProt

A2STJ3 - RNP4_METLZ

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Protein

Ribonuclease P protein component 4

Gene

rnp4

Organism
Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

Cofactori

Binds 1 zinc ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi62 – 621ZincUniRule annotation
Metal bindingi65 – 651ZincUniRule annotation
Metal bindingi88 – 881ZincUniRule annotation
Metal bindingi91 – 911ZincUniRule annotation

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-HAMAP
  2. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. ER to Golgi vesicle-mediated transport Source: InterPro
  2. intracellular protein transport Source: InterPro
  3. tRNA 5'-leader removal Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciMLAB410358:GH7C-1541-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 4UniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P component 4UniRule annotation
Alternative name(s):
Rpp21UniRule annotation
Gene namesi
Name:rnp4UniRule annotation
Ordered Locus Names:Mlab_1485
OrganismiMethanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)
Taxonomic identifieri410358 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanocorpusculaceaeMethanocorpusculum
ProteomesiUP000000365: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. COPII vesicle coat Source: InterPro
  2. ribonuclease P complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 106106Ribonuclease P protein component 4PRO_1000194596Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

Protein-protein interaction databases

STRINGi410358.Mlab_1485.

Structurei

3D structure databases

ProteinModelPortaliA2STJ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic/archaeal RNase P protein component 4 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2023.
HOGENOMiHOG000230709.
KOiK03540.
OMAiPRKWKRR.

Family and domain databases

HAMAPiMF_00757. RNase_P_4.
InterProiIPR016432. RNase_P_comp-4.
IPR007175. Rpr2.
IPR006895. Znf_Sec23_Sec24.
[Graphical view]
PANTHERiPTHR14742. PTHR14742. 1 hit.
PfamiPF04032. Rpr2. 1 hit.
[Graphical view]
PIRSFiPIRSF004878. RNase_P_4. 1 hit.
SUPFAMiSSF82919. SSF82919. 1 hit.

Sequencei

Sequence statusi: Complete.

A2STJ3 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKAEKGVSA KKIAQERVDI LFERAKEARD EPELSARYVS LAREMAMKQR
60 70 80 90 100
VRLAHYHRRS FCPSCHAYFI PGTNLRVRIQ HGKIIYTCGI CGAVTRIPLN

KKTESR
Length:106
Mass (Da):12,159
Last modified:March 6, 2007 - v1
Checksum:i319BD5A85DF10FA1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000559 Genomic DNA. Translation: ABN07649.1.
RefSeqiYP_001030916.1. NC_008942.1.

Genome annotation databases

EnsemblBacteriaiABN07649; ABN07649; Mlab_1485.
GeneIDi4795482.
KEGGimla:Mlab_1485.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000559 Genomic DNA. Translation: ABN07649.1 .
RefSeqi YP_001030916.1. NC_008942.1.

3D structure databases

ProteinModelPortali A2STJ3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 410358.Mlab_1485.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABN07649 ; ABN07649 ; Mlab_1485 .
GeneIDi 4795482.
KEGGi mla:Mlab_1485.

Phylogenomic databases

eggNOGi COG2023.
HOGENOMi HOG000230709.
KOi K03540.
OMAi PRKWKRR.

Enzyme and pathway databases

BioCyci MLAB410358:GH7C-1541-MONOMER.

Family and domain databases

HAMAPi MF_00757. RNase_P_4.
InterProi IPR016432. RNase_P_comp-4.
IPR007175. Rpr2.
IPR006895. Znf_Sec23_Sec24.
[Graphical view ]
PANTHERi PTHR14742. PTHR14742. 1 hit.
Pfami PF04032. Rpr2. 1 hit.
[Graphical view ]
PIRSFi PIRSF004878. RNase_P_4. 1 hit.
SUPFAMi SSF82919. SSF82919. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43576 / DSM 4855 / Z.

Entry informationi

Entry nameiRNP4_METLZ
AccessioniPrimary (citable) accession number: A2STJ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 6, 2007
Last modified: October 29, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3