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A2ST67 (A2ST67_METLZ) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine hydroxymethyltransferase HAMAP MF_00051
Short name=SHMT HAMAP MF_00051
Short name=Serine methylase HAMAP MF_00051
EC=2.1.2.1 HAMAP MF_00051
Gene names
Name:glyA HAMAP MF_00051
Ordered Locus Names:Mlab_1356
OrganismMethanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) [Complete proteome] [HAMAP]
Taxonomic identifier410358 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Methanocorpusculaceae › Methanocorpusculum

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Interconversion of serine and glycine By similarity. HAMAP MF_00051

Catalytic activity

5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. HAMAP MF_00051

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_00051

Pathway

One-carbon metabolism; tetrahydrofolate interconversion. HAMAP MF_00051

Subcellular location

Cytoplasm By similarity HAMAP MF_00051.

Sequence similarities

Belongs to the SHMT family. RuleBase RU004104 HAMAP MF_00051

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2261N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_00051

Sequences

Sequence LengthMass (Da)Tools
A2ST67 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: 6401D97CAE14EC48

FASTA41645,523
        10         20         30         40         50         60 
MSSLALFDPE IFQLINKEHK RQVEGLELIA SENVVAREVM EAMGTILTNK YAEGYPGKRY 

        70         80         90        100        110        120 
YGGCEFHDQI ENLARDRLCQ LFGAEHANVQ PHSGSQANEA VYLSCLKPGD KILSQSLNNG 

       130        140        150        160        170        180 
GHLSHGDPAN MSGKCFDISF YGVDFDTERL DYGVIEELAR KNKPDLIVCG ASAYPREIDF 

       190        200        210        220        230        240 
KAFAEIAEDV GARSMADIAH ISGLCCTGLH NSPVGVTTYT TSTTHKTLRG PRGGVIMCNK 

       250        260        270        280        290        300 
EYANSIDKAV FPGMQGGPLM HVIAAKAVCF REALTDDYKE YAKQVVKNCK VLAATLEDNN 

       310        320        330        340        350        360 
FRLVSGGTDN HLCLLDLSDH NISGQQAEVA LGKAGITVNK NTIPRQALSP FETSGIRIGT 

       370        380        390        400        410 
PTITTRGMKE EQCKQIGDWI AKVLNHIDDE KTIAGVKDEV TSLCLKYPLY PEIRTL

« Hide

References

[1]"Complete genome sequence of Methanocorpusculum labreanum type strain Z."
Anderson I.J., Sieprawska-Lupa M., Goltsman E., Lapidus A., Copeland A., Glavina Del Rio T., Tice H., Dalin E., Barry K., Pitluck S., Hauser L., Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.
Stand. Genomic Sci. 1:197-203(2009)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43576 / DSM 4855 / Z.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000559 Genomic DNA. Translation: ABN07523.1.
RefSeqYP_001030790.1. NC_008942.1.

3D structure databases

ProteinModelPortalA2ST67.
SMRA2ST67. Positions 1-404.
ModBaseSearch...

Protein-protein interaction databases

STRINGA2ST67.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4794899.
GenomeReviewsGene locus Mlab_1356 in contig CP000559_GR.
KEGGmla:Mlab_1356.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG04649.
HOGENOMHBG301263.
OMAMMHRYAE.
ProtClustDBPRK00011.

Family and domain databases

HAMAPMF_00051. SHMT.
[Tree]
InterProIPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR001085. Ser_HO-MeTrfase.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00600.
PANTHERPTHR11680. Gly_HO-Metrfase. 1 hit.
PfamPF00464. SHMT. 1 hit.
[Graphical view]
PIRSFPIRSF000412. SHMT. 1 hit.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA2ST67_METLZ
AccessionPrimary (citable) accession number: A2ST67
Entry history
Integrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info