A2ST53 (RNP2_METLZ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 2
Short name=RNase P component 2
EC=3.1.26.5

Gene names

Name:	rnp2
Ordered Locus Names:	Mlab_1342

Organism

Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) [Complete proteome] [HAMAP]

Taxonomic identifier

410358 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Methanocorpusculaceae › Methanocorpusculum › Methanocorpusculum labreanum

Protein attributes

Sequence length	147 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00755
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00755
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular_function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 147	147	Ribonuclease P protein component 2 HAMAP-Rule MF_00755		PRO_1000148366

Sequences

	Sequence		Length	Mass (Da)
	A2ST53 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: 319F4C8535192CC7	FASTA	147	16,212
	10 20 30 40 50 60 MSVLPPTLRE NRRYVLFRII TLVNPTQKEV YRSMADSVSA LFGDAGAAKM HPAVVWSEGE 70 80 90 100 110 120 YAIARCTRGY EQSLIAALAV VTKVCGEPAS FRSLATSGTI LSLKKKVIPE SIDDTTYPGY 130 140 LCAGKKVNNL SKENGHRYLT RDDIIKE

References

[1]

"Complete genome sequence of Methanocorpusculum labreanum type strain Z." Anderson I.J., Sieprawska-Lupa M., Goltsman E., Lapidus A., Copeland A., Glavina Del Rio T., Tice H., Dalin E., Barry K., Pitluck S., Hauser L., Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C. Stand. Genomic Sci. 1:197-203(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43576 / DSM 4855 / Z.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000559 Genomic DNA. Translation: ABN07509.1.
RefSeq	YP_001030776.1. NC_008942.1.
3D structure databases
ProteinModelPortal	A2ST53.
ModBase	Search...
Protein-protein interaction databases
STRING	410358.Mlab_1342.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABN07509; ABN07509; Mlab_1342.
GeneID	4795369.
KEGG	mla:Mlab_1342.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1369.
KO	K03537.
OMA	SKENGHR.
Enzyme and pathway databases
BioCyc	MLAB410358:GH7C-1405-MONOMER.
Family and domain databases
HAMAP	MF_00755. RNase_P_2.
InterPro	IPR002759. RNase_P/MRP_subunit. [Graphical view]
Pfam	PF01900. RNase_P_Rpp14. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNP2_METLZ

Accession

Primary (citable) accession number: A2ST53

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 6, 2007
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program