ID   A2ST38_METLZ            Unreviewed;       223 AA.
AC   A2ST38;
DT   06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2007, sequence version 1.
DT   27-MAR-2024, entry version 67.
DE   RecName: Full=Fructose-1,6-bisphosphate aldolase/phosphatase {ECO:0000256|ARBA:ARBA00018635};
DE            EC=3.1.3.11 {ECO:0000256|ARBA:ARBA00013093};
GN   OrderedLocusNames=Mlab_1327 {ECO:0000313|EMBL:ABN07494.1};
OS   Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanocorpusculaceae; Methanocorpusculum.
OX   NCBI_TaxID=410358 {ECO:0000313|EMBL:ABN07494.1, ECO:0000313|Proteomes:UP000000365};
RN   [1] {ECO:0000313|EMBL:ABN07494.1, ECO:0000313|Proteomes:UP000000365}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43576 / DSM 4855 / Z {ECO:0000313|Proteomes:UP000000365};
RX   PubMed=21304657; DOI=10.4056.sigs.35575;
RA   Anderson I.J., Sieprawska-Lupa M., Goltsman E., Lapidus A., Copeland A.,
RA   Glavina Del Rio T., Tice H., Dalin E., Barry K., Pitluck S., Hauser L.,
RA   Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.;
RT   "Complete genome sequence of Methanocorpusculum labreanum type strain Z.";
RL   Stand. Genomic Sci. 1:197-203(2009).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-
CC         phosphate + phosphate; Xref=Rhea:RHEA:11064, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:32966, ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=3.1.3.11;
CC         Evidence={ECO:0000256|ARBA:ARBA00001273};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC       {ECO:0000256|ARBA:ARBA00004742}.
CC   -!- SUBUNIT: Homooctamer; dimer of tetramers.
CC       {ECO:0000256|ARBA:ARBA00011820}.
CC   -!- SIMILARITY: Belongs to the FBP aldolase/phosphatase family.
CC       {ECO:0000256|ARBA:ARBA00010693}.
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DR   EMBL; CP000559; ABN07494.1; -; Genomic_DNA.
DR   RefSeq; WP_011833697.1; NC_008942.1.
DR   AlphaFoldDB; A2ST38; -.
DR   STRING; 410358.Mlab_1327; -.
DR   GeneID; 4796080; -.
DR   KEGG; mla:Mlab_1327; -.
DR   eggNOG; arCOG04180; Archaea.
DR   HOGENOM; CLU_1067978_0_0_2; -.
DR   OrthoDB; 5829at2157; -.
DR   UniPathway; UPA00138; -.
DR   Proteomes; UP000000365; Chromosome.
DR   GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002803; FBPase_V.
DR   InterPro; IPR036076; FBPase_V_sf.
DR   PANTHER; PTHR38341; FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE/PHOSPHATASE; 1.
DR   PANTHER; PTHR38341:SF1; FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE_PHOSPHATASE; 1.
DR   Pfam; PF01950; FBPase_3; 2.
DR   SUPFAM; SSF111249; Sulfolobus fructose-1,6-bisphosphatase-like; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW   Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000365};
KW   Schiff base {ECO:0000256|ARBA:ARBA00023270}.
SQ   SEQUENCE   223 AA;  23876 MW;  B057D9DABC2FC830 CRC64;
     MHTTVSVFAK PVGGVSGTTR VFPDILQTAA KMLKKAEGGI LTDSFVTHTA DRLVLIAVHD
     PDVLPDTLIA AVFSAAEELA QKRHLFCDAA PVSVCRMTIP ERANEPFLLF LAGSDVMPWG
     EVMTPGRDSD DACIVDGVLF LARAEGEFPS VAAFCERFAR RGVNQQGVCP VSLCDSSNVR
     TTVIPVVGLG FSLCDGRLAG PVDLFDTPLF DAPRFRASDQ HAE
//