A2SR62 (APGM_METLZ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=aPGAM
EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	Mlab_0645

Organism

Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) [Complete proteome] [HAMAP]

Taxonomic identifier

410358 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Methanocorpusculaceae › Methanocorpusculum

Protein attributes

Sequence length	406 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402_A
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402_A
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402_A
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: InterPro phosphoglycerate mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 406	406	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402_A		PRO_1000068382

Sequences

	Sequence		Length	Mass (Da)
	A2SR62 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: D6726F1AC48BA904	FASTA	406	43,211
	10 20 30 40 50 60 MTASKILLLI IDGVGDRPCG VLGNKTPLQA AKIPNLDRLA TEGICGIMDP IAPGVRGGSD 70 80 90 100 110 120 TSHLSLLGYD PHIYYTGRGP LEAAGCGIKM EPGMIGFRAN YATIDDDGNV IDRRAGRIPD 130 140 150 160 170 180 TTEITAAVKN GVDLSKYGVE IEFSPGTGHR AALALKGKGL SAAVSSNDPK KTGVQPKTIH 190 200 210 220 230 240 PDDDSKEAAF TAEVCNEFSR QAAEILKNHP VNLERKARGE FPANVVLIRG AGEMGVYETF 250 260 270 280 290 300 EEKHELSGSV VAAAALIAGI GSSVGLERIP VLPTTPLDEQ VRLVCRELEK KDFVLFNVKT 310 320 330 340 350 360 ADEYGHDGKA VEKTKYLEEV DAALLPFFDM PELMIAVCGD HSTPCTIKEH SADPVPLILH 370 380 390 400 GDGTRIDLVT NYDEISCAAG GLCRISGGSL MPILLDLIDK THKYGA

References

[1]

"Complete genome sequence of Methanocorpusculum labreanum type strain Z." Anderson I.J., Sieprawska-Lupa M., Goltsman E., Lapidus A., Copeland A., Glavina Del Rio T., Tice H., Dalin E., Barry K., Pitluck S., Hauser L., Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C. Stand. Genomic Sci. 1:197-203(2009) [PubMed: 21304657] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43576 / DSM 4855 / Z.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000559 Genomic DNA. Translation: ABN06818.1.
RefSeq	YP_001030085.1. NC_008942.1.
3D structure databases
ProteinModelPortal	A2SR62.
ModBase	Search...
Protein-protein interaction databases
STRING	A2SR62.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4794934.
GenomeReviews	Gene locus Mlab_0645 in contig CP000559_GR.
KEGG	mla:Mlab_0645.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG04733.
HOGENOM	HBG463247.
OMA	DIAFRCN.
ProtClustDB	CLSK734628.
Enzyme and pathway databases
BioCyc	MLAB410358:MLAB_0645-MONOMER.
Family and domain databases
HAMAP	MF_01402_A. ApgM_A. [Tree]
InterPro	IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR023665. ApgAM. IPR004456. BisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Gene3D	G3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KO	K15635.
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
SUPFAM	SSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMs	TIGR00306. ApgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_METLZ

Accession

Primary (citable) accession number: A2SR62

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	March 6, 2007
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program