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A2SQX8 (A2SQX8_METLZ) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Diaminopimelate epimerase HAMAP MF_00197

Short name=DAP epimerase HAMAP MF_00197
EC=5.1.1.7 HAMAP MF_00197
Gene names
Name:dapF HAMAP MF_00197
Ordered Locus Names:Mlab_0560
OrganismMethanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) [Complete proteome] [HAMAP]
Taxonomic identifier410358 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanocorpusculaceaeMethanocorpusculum

Protein attributes

Sequence length274 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197

Subcellular location

Cytoplasm By similarity HAMAP MF_00197.

Sequence similarities

Belongs to the diaminopimelate epimerase family. HAMAP MF_00197

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Lysine biosynthesis HAMAP MF_00197
   Cellular componentCytoplasm HAMAP MF_00197
   Molecular functionIsomerase HAMAP MF_00197 EMBL ABN06734.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processlysine biosynthetic process via diaminopimelate

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondiaminopimelate epimerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site861 By similarity HAMAP MF_00197
Active site2191 By similarity HAMAP MF_00197

Sequences

Sequence LengthMass (Da)Tools
A2SQX8 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: 753E9E0FAB303111

FASTA27429,570
        10         20         30         40         50         60 
MTIKFPKHDL RSIAFTKLHG NGNDFILIDE MDQVIIPDDM KAQFAVVYCD RRFGIGGDGV 

        70         80         90        100        110        120 
LFISKSDKAD IRMRLFQPDA SEAEMCGNGI RCLSKYAFDK EYAKKKAFSV ETLAGVMQVR 

       130        140        150        160        170        180 
VGYDSDGDFM ATIDMGTAVY DESREIDGMT VYSVNTGVPH AVIFVGNVDG IAINEVAPKI 

       190        200        210        220        230        240 
RHHPSFPKGT NVNFVQITGS SEIVIRTFER GVEGETLSCG TGSTASALIA AKTGKTHGSV 

       250        260        270 
VHVKTVGGPL DITVGDIPQM TGPAATVFVG EIQY 

« Hide

References

[1]"Complete genome sequence of Methanocorpusculum labreanum type strain Z."
Anderson I.J., Sieprawska-Lupa M., Goltsman E., Lapidus A., Copeland A., Glavina Del Rio T., Tice H., Dalin E., Barry K., Pitluck S., Hauser L., Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.
Stand. Genomic Sci. 1:197-203(2009)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43576 / DSM 4855 / Z.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000559 Genomic DNA. Translation: ABN06734.1.
RefSeqYP_001030001.1. NC_008942.1.

3D structure databases

ProteinModelPortalA2SQX8.
ModBaseSearch...

Protein-protein interaction databases

STRINGA2SQX8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4796174.
GenomeReviewsGene locus Mlab_0560 in contig CP000559_GR.
KEGGmla:Mlab_0560.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG07445.
HOGENOMHBG399442.
OMANTGVPHV.
PhylomeDBA2SQX8.
ProtClustDBPRK00450.

Family and domain databases

HAMAPMF_00197. DAP_epimerase.
[Tree]
InterProIPR001653. DAP_epimerase_DapF.
[Graphical view]
KOK01778.
PfamPF01678. DAP_epimerase. 2 hits.
[Graphical view]
TIGRFAMsTIGR00652. DapF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA2SQX8_METLZ
AccessionPrimary (citable) accession number: A2SQX8
Entry history
Integrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: November 16, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)