A2SQW1 (DCD_METLZ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Mlab_0543

Organism

Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) [Complete proteome] [HAMAP]

Taxonomic identifier

410358 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Methanocorpusculaceae › Methanocorpusculum

Protein attributes

Sequence length	187 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 187	187	Probable deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000117983

Sequences

	Sequence		Length	Mass (Da)
	A2SQW1 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: F3E606FB89884D34	FASTA	187	21,241
	10 20 30 40 50 60 MILVDWEIAD HIKRGYIGID PFDPALVQPN SLDIRLGNHF VWYEPCDDVI DPYQKETLHT 70 80 90 100 110 120 HTQERKGSYF DIQPGQFVLA ETLETVTLPD NIVSSIEGKS SVARLGIALH QTGGWIDAGF 130 140 150 160 170 180 SGTITLEMCN SNCRPVRVYA GMPIGQLVFY VTKRCECPYD KKPDAKYQNQ KNATISRYDR KMLKNVE

References

[1]

"Complete genome sequence of Methanocorpusculum labreanum type strain Z." Anderson I.J., Sieprawska-Lupa M., Goltsman E., Lapidus A., Copeland A., Glavina Del Rio T., Tice H., Dalin E., Barry K., Pitluck S., Hauser L., Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C. Stand. Genomic Sci. 1:197-203(2009) [PubMed: 21304657] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43576 / DSM 4855 / Z.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000559 Genomic DNA. Translation: ABN06717.1.
RefSeq	YP_001029984.1. NC_008942.1.
3D structure databases
ProteinModelPortal	A2SQW1.
ModBase	Search...
Protein-protein interaction databases
STRING	A2SQW1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4795909.
GenomeReviews	Gene locus Mlab_0543 in contig CP000559_GR.
KEGG	mla:Mlab_0543.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG05800.
HOGENOM	HBG553199.
OMA	HQTAGWI.
PhylomeDB	A2SQW1.
ProtClustDB	CLSK949569.
Enzyme and pathway databases
BioCyc	MLAB410358:MLAB_0543-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_METLZ

Accession

Primary (citable) accession number: A2SQW1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	March 6, 2007
Last modified:	November 16, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program