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Protein
Submitted name:

L-lysine 2,3-aminomutase

Gene

Mlab_0345

Organism
Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Cofactori

pyridoxal 5'-phosphateUniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi149 – 1491Iron-sulfur (4Fe-4S-S-AdoMet)UniRule annotation
Metal bindingi153 – 1531Iron-sulfur (4Fe-4S-S-AdoMet)UniRule annotation
Metal bindingi156 – 1561Iron-sulfur (4Fe-4S-S-AdoMet)UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseImported

Keywords - Ligandi

4Fe-4SUniRule annotation, Iron, Iron-sulfur, Metal-binding, Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciMLAB410358:GH7C-351-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
L-lysine 2,3-aminomutaseImported (EC:5.4.3.2Imported)
Gene namesi
Ordered Locus Names:Mlab_0345Imported
OrganismiMethanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)Imported
Taxonomic identifieri410358 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanocorpusculaceaeMethanocorpusculum
ProteomesiUP000000365 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei361 – 3611N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi410358.Mlab_0345.

Structurei

3D structure databases

ProteinModelPortaliA2SQB5.
SMRiA2SQB5. Positions 28-446.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini145 – 259115Radical_SAMInterPro annotationAdd
BLAST
Domaini336 – 451116LAM_CInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiarCOG03246. Archaea.
COG1509. LUCA.
HOGENOMiHOG000223518.
KOiK01843.
OMAiGVNDCPR.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR025895. LAM_C_dom.
IPR003739. Lys_aminomutase/Glu_NH3_mut.
IPR022459. Lysine_aminomutase.
IPR007197. rSAM.
[Graphical view]
PfamiPF12544. LAM_C. 1 hit.
PF04055. Radical_SAM. 1 hit.
[Graphical view]
PIRSFiPIRSF004911. DUF160. 1 hit.
TIGRFAMsiTIGR03820. lys_2_3_AblA. 1 hit.
TIGR00238. TIGR00238. 1 hit.

Sequencei

Sequence statusi: Complete.

A2SQB5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLQTESLEK TADTETQTNE SGAFSKGRYA GIDDGEYWKN WKWQVRHAVR
60 70 80 90 100
SIDMVQQVLG ITFDPKEREE LQRTVEKFPI SITPYYLSLI DTEDYRNDPI
110 120 130 140 150
FRQAFPSPAE LIVENYELSD PLAEDKDSPC ECITHRYPDR VLFLVSNTCA
160 170 180 190 200
MYCRHCTRKR KVGDKDSIPD REKILEGIAY IRENTQIRDV LLSGGDPFML
210 220 230 240 250
SDESLDWILT ELTAIPHVEV IRIGTRVPVV LPFRITNQLV DILKKHKPIW
260 270 280 290 300
INTQFNHPKE MTPSAQAAVA KLVDAGIPLG NQSVLLARIN DCPVIMKELV
310 320 330 340 350
HQLVKNRIRP YYLYQCDLSE GISHFRTPIA KGIEIMESLI GHTSGFAVPR
360 370 380 390 400
YVVDAPGGGG KIPVSPNYLL TWSVNKVVLR NYEGIICTYQ EPAVYDRIIC
410 420 430 440 450
DQNCDACKLQ LNIRNADESK VVGVAKLLAD YDDTTTLIPE NNERLERRED

ETN
Length:453
Mass (Da):51,633
Last modified:March 6, 2007 - v1
Checksum:i3B17688016472501
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000559 Genomic DNA. Translation: ABN06521.1.

Genome annotation databases

EnsemblBacteriaiABN06521; ABN06521; Mlab_0345.
KEGGimla:Mlab_0345.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000559 Genomic DNA. Translation: ABN06521.1.

3D structure databases

ProteinModelPortaliA2SQB5.
SMRiA2SQB5. Positions 28-446.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi410358.Mlab_0345.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABN06521; ABN06521; Mlab_0345.
KEGGimla:Mlab_0345.

Phylogenomic databases

eggNOGiarCOG03246. Archaea.
COG1509. LUCA.
HOGENOMiHOG000223518.
KOiK01843.
OMAiGVNDCPR.

Enzyme and pathway databases

BioCyciMLAB410358:GH7C-351-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR025895. LAM_C_dom.
IPR003739. Lys_aminomutase/Glu_NH3_mut.
IPR022459. Lysine_aminomutase.
IPR007197. rSAM.
[Graphical view]
PfamiPF12544. LAM_C. 1 hit.
PF04055. Radical_SAM. 1 hit.
[Graphical view]
PIRSFiPIRSF004911. DUF160. 1 hit.
TIGRFAMsiTIGR03820. lys_2_3_AblA. 1 hit.
TIGR00238. TIGR00238. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43576 / DSM 4855 / ZImported.

Entry informationi

Entry nameiA2SQB5_METLZ
AccessioniPrimary (citable) accession number: A2SQB5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: December 9, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.