A2SPR4 (A2SPR4_METLZ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase RuleBase RU004370
EC=6.3.3.1 RuleBase RU004370

Gene names

Ordered Locus Names:

Mlab_0143

Organism

Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) [Complete proteome] [HAMAP]

Taxonomic identifier

410358 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Methanocorpusculaceae › Methanocorpusculum

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. RuleBase RU004370
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. RuleBase RU004371
Sequence similarities	Belongs to the AIR synthase family. RuleBase RU004370

Ontologies

Keywords
Molecular function	Ligase RuleBase RU004370 EMBL ABN06320.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	phosphoribosylformylglycinamidine cyclo-ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2SPR4 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: 355E9134E678685C	FASTA	331	35,509
	10 20 30 40 50 60 MTKKYSYKEA GVDINLEADG VKALIHQLSY KRTGEHGMVG DVGHFAGMID FGSKVLSLCT 70 80 90 100 110 120 DGVGTKMRIA DDLKDWTTVG IDCMAMNVND MYVMNIEPIA FVDYIATEGI NTEQMIQIGV 130 140 150 160 170 180 GLNEGARLSN LNIVGGETAT LKGMINGLDL AGTCLGVQDK DKVVTGEKVA PGDIIIGVAS 190 200 210 220 230 240 TGVHSNGYTL ARKVAEENGG YATVLLSGRT VGEALLVPTR IYSEVLDVCS KAVVHGMCHV 250 260 270 280 290 300 TGGGLLNFLR ISSYGFAIED PLEVPEILAW IAEKGNLEMN ELYRTFNMGM GFAFIVPKES 310 320 330 VETVLSMVEG SKVVGRVIEE HKVTLKGVEV Y

References

[1]

"Complete genome sequence of Methanocorpusculum labreanum type strain Z." Anderson I.J., Sieprawska-Lupa M., Goltsman E., Lapidus A., Copeland A., Glavina Del Rio T., Tice H., Dalin E., Barry K., Pitluck S., Hauser L., Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C. Stand. Genomic Sci. 1:197-203(2009) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43576 / DSM 4855 / Z.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000559 Genomic DNA. Translation: ABN06320.1.
RefSeq	YP_001029587.1. NC_008942.1.
3D structure databases
ProteinModelPortal	A2SPR4.
ModBase	Search...
Protein-protein interaction databases
STRING	A2SPR4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4795435.
GenomeReviews	Gene locus Mlab_0143 in contig CP000559_GR.
KEGG	mla:Mlab_0143.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG04189.
HOGENOM	HBG531222.
OMA	GIDMIAM.
ProtClustDB	CLSK949966.
Family and domain databases
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004733. PurM_cligase. IPR016188. PurM_N-like. [Graphical view]
KO	K01933.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00878. PurM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A2SPR4_METLZ

Accession

Primary (citable) accession number: A2SPR4

Entry history

Integrated into UniProtKB/TrEMBL:	March 6, 2007
Last sequence update:	March 6, 2007
Last modified:	November 16, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)