A2SKF9 (TAL_METPP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transaldolase
EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	Mpe_A3095

Organism

Methylibium petroleiphilum (strain PM1) [Complete proteome] [HAMAP]

Taxonomic identifier

420662 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Methylibium

Protein attributes

Sequence length	316 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00492
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00492
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00492
Subcellular location	Cytoplasm By similarity HAMAP MF_00492.
Sequence similarities	Belongs to the transaldolase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 316	316	Transaldolase HAMAP MF_00492		PRO_1000014504
Sites
	Active site	126	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A2SKF9 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: 2D814C21131CFFB4	FASTA	316	34,033
	10 20 30 40 50 60 MSSQLEQLKA YTTVVADTGD FKQIAAFAPR DATTNPSLIL KAVSQPAYAP LLAQTAAAHR 70 80 90 100 110 120 GQPLDAIVDR VLVRFGCEIL NVVPGRVSTE VDARLSFDAA ATVARAQRIM ALYESEGIAR 130 140 150 160 170 180 ERVLIKIAAT WEGIQAAKAL EHHGIHCNLT LLFAFCQAVA CGESGVRLIS PFVGRIHDWH 190 200 210 220 230 240 KKAAGARWDE AANAGANDPG VKSVAQIWRY FRKFGIETEV MGASFRNTGQ ILALAGCDLL 250 260 270 280 290 300 TISPELLAQL QASEATVMRA LDVDAALHCD AKALSFNEAS FRYALNEDAM ATEKLAEGIR 310 AFAVDAAQLD RLIQAL

References

[1]

"Whole-genome analysis of the methyl tert-butyl ether-degrading beta-proteobacterium Methylibium petroleiphilum PM1." Kane S.R., Chakicherla A.Y., Chain P.S.G., Schmidt R., Shin M.W., Legler T.C., Scow K.M., Larimer F.W., Lucas S.M., Richardson P.M., Hristova K.R. J. Bacteriol. 189:1931-1945(2007) [PubMed: 17158667] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PM1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000555 Genomic DNA. Translation: ABM96048.1.
RefSeq	YP_001022283.1. NC_008825.1.
3D structure databases
ProteinModelPortal	A2SKF9.
SMR	A2SKF9. Positions 1-315.
ModBase	Search...
Protein-protein interaction databases
STRING	A2SKF9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4786668.
GenomeReviews	Gene locus Mpe_A3095 in contig CP000555_GR.
KEGG	mpt:Mpe_A3095.
NMPDR	fig|279263.3.peg.387.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0176.
HOGENOM	HBG286747.
OMA	GCEILAI.
PhylomeDB	A2SKF9.
ProtClustDB	PRK05269.
Enzyme and pathway databases
BioCyc	MPET420662:MPE_A3095-MONOMER.
Family and domain databases
HAMAP	MF_00492. Transaldolase_1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004730. Transaldolase_1. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00616.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00874. TalAB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_METPP

Accession

Primary (citable) accession number: A2SKF9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	March 6, 2007
Last modified:	November 16, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program