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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Methylibium petroleiphilum (strain PM1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei154 – 1541UniRule annotation
Active sitei586 – 5861UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciMPET420662:GHBE-3040-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Mpe_A3003Imported
OrganismiMethylibium petroleiphilum (strain PM1)Imported
Taxonomic identifieri420662 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesMethylibium
ProteomesiUP000000366 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi420662.Mpe_A3003.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2SK67-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATAKTPRSA DRGADKNRPL IEDIRLLGRI LGDVIREQEG ALAFELIERI
60 70 80 90 100
RQLAVAYRLK RDTQAGRALD RLLKNLSVEQ AVSVVRAFSY FSHLANLAED
110 120 130 140 150
RHHVRRREHH EQLGHVQEGS LAMSFERLAK RGVRATEIAE LLGHAYLSPV
160 170 180 190 200
LTAHPTEVQR KSVLDAERAV AELIGARDTL PTQRERAANE AMLRARVTQL
210 220 230 240 250
WQTRLLRTSK LSVANEIDNA LSYYQSTFLR QIPRLYAELE ALLPGFEVAP
260 270 280 290 300
FFRMGNWIGG DRDGNPNVTA ETLRLALARH SETVLRFYLT EVHELGAELS
310 320 330 340 350
ISALLVQVTP ELQALADRSG DHNAHRLDEP YRRALIGVYA RLAGTLTALT
360 370 380 390 400
GTEALRHAVA PSTPYATAEE LLADLRTVEA SLASHHGAAL AAARLKPLIR
410 420 430 440 450
AVQVFGFHLA TVDLRQSSDQ HEAVLAELMA GARIEADYAA MPEEAKVALL
460 470 480 490 500
LGLLNDARSL QVRGAVYSER TRGELAIFEA AREGRALYGH AAIRHCIISH
510 520 530 540 550
TETVSDLLEV LVLQKEAGLL QGTLDTDARC DLIVVPLFET ITDLRQAAPI
560 570 580 590 600
MREFYALPGV LPLVLRSGAD QYCEQDVMLG YSDSNKDGGF FTSNWELYRA
610 620 630 640 650
ETALVELFEP LKREHGLTLR LFHGRGGTVG RGGGPSYQAI LAQPPGTVNG
660 670 680 690 700
QIRLTEQGEV IASKYANPEI GRRNLETLVA ATLEATLLPP KRHAPKLFLD
710 720 730 740 750
TADTLSQLSM AAYRKLVYET PGFADYFFAA TPIREIAELN IGSRPASRKA
760 770 780 790 800
TRAIEDLRAI PWGFSWGQCR VALPGWYGFG SAVEGFLGDA PKQRKERLAL
810 820 830 840 850
LQRMHAQWPF FGTLLSNIDM VLAKSDLAIA TRYVELVPDK RAAKKIFAAV
860 870 880 890 900
QAEWQRTDAV LAAITGEPRR LAGNAALARS IEHRLPYIDP LNHLQVELMR
910 920 930
RYRAQQGRGE LHERVQRGIH MSINGVAAGL RNSG
Length:934
Mass (Da):103,374
Last modified:March 6, 2007 - v1
Checksum:iF3AEAF3836547EB2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000555 Genomic DNA. Translation: ABM95956.1.
RefSeqiWP_011830579.1. NC_008825.1.
YP_001022191.1. NC_008825.1.

Genome annotation databases

EnsemblBacteriaiABM95956; ABM95956; Mpe_A3003.
KEGGimpt:Mpe_A3003.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000555 Genomic DNA. Translation: ABM95956.1.
RefSeqiWP_011830579.1. NC_008825.1.
YP_001022191.1. NC_008825.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi420662.Mpe_A3003.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM95956; ABM95956; Mpe_A3003.
KEGGimpt:Mpe_A3003.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciMPET420662:GHBE-3040-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Whole-genome analysis of the methyl tert-butyl ether-degrading beta-proteobacterium Methylibium petroleiphilum PM1."
    Kane S.R., Chakicherla A.Y., Chain P.S.G., Schmidt R., Shin M.W., Legler T.C., Scow K.M., Larimer F.W., Lucas S.M., Richardson P.M., Hristova K.R.
    J. Bacteriol. 189:1931-1945(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PM1Imported.

Entry informationi

Entry nameiA2SK67_METPP
AccessioniPrimary (citable) accession number: A2SK67
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: June 24, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.