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A2SJL1 (PSD_METPP) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:Mpe_A2796
OrganismMethylibium petroleiphilum (strain PM1) [Complete proteome] [HAMAP]
Taxonomic identifier420662 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Methylibium

Protein attributes

Sequence length283 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 247247Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000026560
Chain248 – 28336Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000026561

Sites

Site247 – 2482Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2481Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
A2SJL1 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: 1133E9372D6D6309

FASTA28331,496
        10         20         30         40         50         60 
MSERLPVLLQ YLVPQRALTV FAGFVASGRW GGITTAIIRR FVRKYRVDMS EAAEPDIARY 

        70         80         90        100        110        120 
TRFNDFFTRA LRPGARPLAS AELVCPVDGA ISQFGAIERD QIFQAKGHHY STRALVGGDA 

       130        140        150        160        170        180 
ELAARFQDGQ FATLYLSPRD YHRIHMPCDG RLLRMIHVPG DLFSVNPVTA RGVPGLFARN 

       190        200        210        220        230        240 
ERVVCEFDGP LGPFVLVLVG ATIVGSMATV WHGQVNPPRS GRLREWRYAD RELRLRQGEE 

       250        260        270        280 
MGRFLLGSTV VALFPQGSVR FDPGWEPGRA VRLGEAMAFA PLL

« Hide

References

[1]"Whole-genome analysis of the methyl tert-butyl ether-degrading beta-proteobacterium Methylibium petroleiphilum PM1."
Kane S.R., Chakicherla A.Y., Chain P.S.G., Schmidt R., Shin M.W., Legler T.C., Scow K.M., Larimer F.W., Lucas S.M., Richardson P.M., Hristova K.R.
J. Bacteriol. 189:1931-1945(2007) [PubMed: 17158667] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PM1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000555 Genomic DNA. Translation: ABM95750.1.
RefSeqYP_001021985.1. NC_008825.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA2SJL1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4785046.
GenomeReviewsGene locus Mpe_A2796 in contig CP000555_GR.
KEGGmpt:Mpe_A2796.
NMPDRfig|279263.3.peg.3511.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0688.
HOGENOMHBG302256.
OMASMATVWH.
PhylomeDBA2SJL1.
ProtClustDBPRK00044.

Enzyme and pathway databases

BioCycMPET420662:MPE_A2796-MONOMER.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
KOK01613.
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_METPP
AccessionPrimary (citable) accession number: A2SJL1
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 6, 2007
Last modified: November 16, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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