A2SJ01 (A2SJ01_METPP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Pyrroloquinoline-quinone synthase HAMAP MF_00654
EC=1.3.3.11 HAMAP MF_00654

Alternative name(s):
Coenzyme PQQ synthesis protein C HAMAP MF_00654
Pyrroloquinoline quinone biosynthesis protein C HAMAP MF_00654

Gene names

Name:	pqqC HAMAP MF_00654
Ordered Locus Names:	Mpe_A2586

Organism

Methylibium petroleiphilum (strain PM1) [Complete proteome] [HAMAP] EMBL ABM95540.1

Taxonomic identifier

420662 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Methylibium

Protein attributes

Sequence length	243 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. HAMAP MF_00654
Catalytic activity	6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654
Pathway	Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654
Sequence similarities	Belongs to the pqqC family. HAMAP MF_00654

Ontologies

Keywords
Biological process	PQQ biosynthesis HAMAP MF_00654
Molecular function	Oxidoreductase HAMAP MF_00654
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyrroloquinoline quinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	pyrroloquinoline-quinone synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2SJ01 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: 12BC15F6BC2BBFCA	FASTA	243	27,971
	10 20 30 40 50 60 MSADLPWSPA EFEARLRAKE SGYHIHHPFN KRLNSGALQP FQVRGWVANR FYYQQAIPMK 70 80 90 100 110 120 DAAVMANCED RATRRRWIER MLDHDGHGDH EGQNAGGIET WTRLGMAVGL SREDLWSHRH 130 140 150 160 170 180 VQPGVRFAVD AYVNFARRAP WREGVISSLT EMFAPKIHAD RLAGWPSMYP WIAAEGLAYF 190 200 210 220 230 240 RSRIPLAQRD VEHGLEVAIA FGDTRAKQER AIEILQFKLD VLWSLLDAVE RAYPDDLPEE RRP

References

[1]

"Whole-genome analysis of the methyl tert-butyl ether-degrading beta-proteobacterium Methylibium petroleiphilum PM1." Kane S.R., Chakicherla A.Y., Chain P.S.G., Schmidt R., Shin M.W., Legler T.C., Scow K.M., Larimer F.W., Lucas S.M., Richardson P.M., Hristova K.R. J. Bacteriol. 189:1931-1945(2007) [PubMed: 17158667] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000555 Genomic DNA. Translation: ABM95540.1.
RefSeq	YP_001021775.1. NC_008825.1.
3D structure databases
ProteinModelPortal	A2SJ01.
SMR	A2SJ01. Positions 8-238.
ModBase	Search...
Protein-protein interaction databases
STRING	A2SJ01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4787022.
GenomeReviews	Gene locus Mpe_A2586 in contig CP000555_GR.
KEGG	mpt:Mpe_A2586.
NMPDR	fig|279263.3.peg.866.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG5424.
HOGENOM	HBG288944.
OMA	DSWPQHY.
ProtClustDB	PRK05157.
Family and domain databases
HAMAP	MF_00654. PQQ_syn_PqqC. [Tree]
InterPro	IPR016084. Haem_Oase-like_multi-hlx. IPR011845. PQQ_synth_PqqC. IPR004305. TENA/THI4/PQQ_synthPqqC_dom. [Graphical view]
Gene3D	G3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
KO	K06137.
Pfam	PF03070. TENA_THI-4. 1 hit. [Graphical view]
SUPFAM	SSF48613. Heme_oxygenase. 1 hit.
TIGRFAMs	TIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A2SJ01_METPP

Accession

Primary (citable) accession number: A2SJ01

Entry history

Integrated into UniProtKB/TrEMBL:	March 6, 2007
Last sequence update:	March 6, 2007
Last modified:	November 16, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)