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A2SGS9 (A2SGS9_METPP) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADPH-dependent 7-cyano-7-deazaguanine reductase HAMAP MF_00818
EC=1.7.1.13 HAMAP MF_00818
Alternative name(s):
7-cyano-7-carbaguanine reductase HAMAP MF_00818
NADPH-dependent nitrile oxidoreductase HAMAP MF_00818
PreQ(0) reductase HAMAP MF_00818
Gene names
Name:queF HAMAP MF_00818
Ordered Locus Names:Mpe_A1809
OrganismMethylibium petroleiphilum (strain PM1) [Complete proteome] [HAMAP] EMBL ABM94768.1
Taxonomic identifier420662 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Methylibium

Protein attributes

Sequence length161 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) By similarity. HAMAP MF_00818

Catalytic activity

7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH. HAMAP MF_00818

Pathway

tRNA modification; tRNA-queuosine biosynthesis. HAMAP MF_00818

Subcellular location

Cytoplasm By similarity HAMAP MF_00818.

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. HAMAP MF_00818

Sequences

Sequence LengthMass (Da)Tools
A2SGS9 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: AA7471310C597E7A

FASTA16118,294
        10         20         30         40         50         60 
MAKTAKKSSP RTPPRQRPMP PNPPTAPSKE LHVFPNPAPE RDYVIQFQIP EFTCLCPLTG 

        70         80         90        100        110        120 
QPDFAHFTID MIADGLCVEL KSLKMYMWSF RDEGAFHEKV TNDILGKIVE TTAPRFARIT 

       130        140        150        160 
ARWYVRGGIY TNVVAEHRKK GWKPEPLVVL PQHATERGLP T

« Hide

References

[1]"Whole-genome analysis of the methyl tert-butyl ether-degrading beta-proteobacterium Methylibium petroleiphilum PM1."
Kane S.R., Chakicherla A.Y., Chain P.S.G., Schmidt R., Shin M.W., Legler T.C., Scow K.M., Larimer F.W., Lucas S.M., Richardson P.M., Hristova K.R.
J. Bacteriol. 189:1931-1945(2007) [PubMed: 17158667] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000555 Genomic DNA. Translation: ABM94768.1.
RefSeqYP_001021003.1. NC_008825.1.

3D structure databases

ProteinModelPortalA2SGS9.
ModBaseSearch...

Protein-protein interaction databases

STRINGA2SGS9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4786808.
GenomeReviewsGene locus Mpe_A1809 in contig CP000555_GR.
KEGGmpt:Mpe_A1809.
NMPDRfig|279263.3.peg.1279.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0780.
HOGENOMHBG294103.
OMAHEESANQ.

Family and domain databases

HAMAPMF_00818. QueF_type1.
[Tree]
InterProIPR016856. CN_OxRdtase_NADPH-dep_QueF.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
[Graphical view]
KOK09457.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
PIRSFPIRSF027377. Nitrile_oxidored_QueF. 1 hit.
TIGRFAMsTIGR03139. QueF-II. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA2SGS9_METPP
AccessionPrimary (citable) accession number: A2SGS9
Entry history
Integrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: November 16, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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