A2SG05 (A2SG05_METPP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase 2 HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2-2 HAMAP MF_01902
Ordered Locus Names:	Mpe_A1532

Organism

Methylibium petroleiphilum (strain PM1) [Complete proteome] [HAMAP] EMBL ABM94494.1

Taxonomic identifier

420662 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Methylibium

Protein attributes

Sequence length	1099 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2SG05 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: E66989DF9D14FDDA	FASTA	1,099	121,101
	10 20 30 40 50 60 MPQPAHPKTP QPASPPPPPL HWTRPGLPAY AELHCRSNFS FLTGASHPQE LVERAAQLGY 70 80 90 100 110 120 AAIAITDECS VAGVVRAHAA LKRLRENGNP PLPALIIGSE FTLAASPTAP GCRLVLLAKN 130 140 150 160 170 180 REGYAQICGL ITLGRGRSAK GHYQLSVDDL DALLAGQGHA AGVPDCLALL IPRRDEPHAT 190 200 210 220 230 240 LLAQARWLAG RCGERASIAV ELLRWADDES FVERLLDASA ASGLPLAAAG DVLMHVRSRK 250 260 270 280 290 300 PLQDTLTAIR LKRRVADCGY ALMRNAEQHL RSRLALAQLC RPEWLQRSVD LARACDFSLE 310 320 330 340 350 360 QLKYEYPDEI VPAGETASSH LRRLTEEGAC VRYPGGVPGM VQAQIEHEFA LIFRKRYEAF 370 380 390 400 410 420 FLTVHDVVRF ARSEGILCQG RGSAANSAVC YCLGITEVDP TQTPLLFERF ISEERGEAPD 430 440 450 460 470 480 IDVDFEHERR EEVIQYIYGK YGTHRTALAA ALATYRVRGA VREVGKALGL DGQRIDRLAK 490 500 510 520 530 540 SHQWFDGHEA LPARLVEAGF DPDAPVTRQW LALSAALIGF PRHLSQHVGG FVIARDALSR 550 560 570 580 590 600 LVPIENAAMK DRRVIQWDKD DLESLGLLKV DVLALGMLSA LKRALALITD WRGPPPGANG 610 620 630 640 650 660 GAPISPSWRM QDIPRDDIAT YEMIQEADTV GVFQIESRAQ QSMLPRLKPS EFYDLVVQVA 670 680 690 700 710 720 IVRPGPISGG MVHPYLKQRD LQRRGLRPPP AYPALEQALE RTLGVPIFQE QVMQICMIAA 730 740 750 760 770 780 DFSGGDADEL RRAMAAWKRK GGLQQFHQRI VGRMVEKNYD REFAERIFQQ IKGFGEYGFP 790 800 810 820 830 840 ESHAYSFALL AYLSAWLKCH EPAIFLAALL NSQPMGFYAP SQLVQDARRH AVEVRPVDVG 850 860 870 880 890 900 HSGWDCTLEP ASPGSTPCAA RSLQPAVRLG LRLVSGFSEA AADRIVAARA VSTFASLDDL 910 920 930 940 950 960 ARRAGLDPQA LQVLARADAL QSLAGHRRQQ AWHASGQPRR TALLAGATHR EDPLVLPAPP 970 980 990 1000 1010 1020 EAEEITLDYA STQLTLRRHP LALLRPRLVQ RGWRNARELG ALKDGCRVWA CGIVVGRQQP 1030 1040 1050 1060 1070 1080 ETAKGTIFVT LEDETGSVNV IVWKGVRERF RQALLASRLL AVAGEWQRSP EGVTHLLARR 1090 LVDMTPWLGR LATSSRDFH

References

[1]

"Whole-genome analysis of the methyl tert-butyl ether-degrading beta-proteobacterium Methylibium petroleiphilum PM1." Kane S.R., Chakicherla A.Y., Chain P.S.G., Schmidt R., Shin M.W., Legler T.C., Scow K.M., Larimer F.W., Lucas S.M., Richardson P.M., Hristova K.R. J. Bacteriol. 189:1931-1945(2007) [PubMed: 17158667] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000555 Genomic DNA. Translation: ABM94494.1.
RefSeq	YP_001020729.1. NC_008825.1.
3D structure databases
ProteinModelPortal	A2SG05.
ModBase	Search...
Protein-protein interaction databases
STRING	A2SG05.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4783550.
GenomeReviews	Gene locus Mpe_A1532 in contig CP000555_GR.
KEGG	mpt:Mpe_A1532.
NMPDR	fig|279263.3.peg.69.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	LATNRNG.
ProtClustDB	CLSK2321935.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A2SG05_METPP

Accession

Primary (citable) accession number: A2SG05

Entry history

Integrated into UniProtKB/TrEMBL:	March 6, 2007
Last sequence update:	March 6, 2007
Last modified:	November 16, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)