A2SF93 (GLMM_METPP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Mpe_A1270

Organism

Methylibium petroleiphilum (strain PM1) [Complete proteome] [HAMAP]

Taxonomic identifier

420662 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Methylibium

Protein attributes

Sequence length	457 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 457	457	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000301337
Sites
	Active site	106	1	Phosphoserine intermediate By similarity
	Metal binding	106	1	Magnesium; via phosphate group By similarity
	Metal binding	245	1	Magnesium By similarity
	Metal binding	247	1	Magnesium By similarity
	Metal binding	249	1	Magnesium By similarity
Amino acid modifications
	Modified residue	106	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A2SF93 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: 7D2E75174F8E010B	FASTA	457	48,254
	10 20 30 40 50 60 MSRTYFGTDG IRGAVGQAPI TPDFVLRLGH AVGRVLKSQQ TSPASRPTVL IGKDTRISGY 70 80 90 100 110 120 MLESALEAGF ASAGVDVLLT GPLPTPGVAY LTRALRLSLG VVISASHNPY GDNGIKFFSA 130 140 150 160 170 180 KGEKLPDSWE QQVEATVEEA AQWVDSSGLG KARRLDDAQG RYIEFCKSTV AGELSLKGLK 190 200 210 220 230 240 LVVDGAHGAA YQVAPAVFHE LGAEVISIGC NPNGLNINDG FGATHPEALV SAVQAHQADY 250 260 270 280 290 300 GIALDGDADR LQLVDATGRL YNGDELLYLM TLDRLAAEPS EDAAPSRVGV PGVVGTLMTN 310 320 330 340 350 360 LAVEQALAAR GVAFVRAKVG DRYVLEELLA RGWQLGGEGS GHLIALDKHT TGDGLVSALQ 370 380 390 400 410 420 VLQAVVRSGR TLAQLLEGLT LFPQVLLNVR LQPGQDWKAS AALAEAQRES LAELGERGRI 430 440 450 LIRPSGTEPL LRVMVEASDA ALAQRCAQRM ADAVRRA

References

[1]

"Whole-genome analysis of the methyl tert-butyl ether-degrading beta-proteobacterium Methylibium petroleiphilum PM1." Kane S.R., Chakicherla A.Y., Chain P.S.G., Schmidt R., Shin M.W., Legler T.C., Scow K.M., Larimer F.W., Lucas S.M., Richardson P.M., Hristova K.R. J. Bacteriol. 189:1931-1945(2007) [PubMed: 17158667] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PM1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000555 Genomic DNA. Translation: ABM94232.1.
RefSeq	YP_001020467.1. NC_008825.1.
3D structure databases
ProteinModelPortal	A2SF93.
ModBase	Search...
Protein-protein interaction databases
STRING	A2SF93.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4785847.
GenomeReviews	Gene locus Mpe_A1270 in contig CP000555_GR.
KEGG	mpt:Mpe_A1270.
NMPDR	fig|279263.3.peg.1595.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	PLEDIQV.
PhylomeDB	A2SF93.
ProtClustDB	PRK10887.
Enzyme and pathway databases
BioCyc	MPET420662:MPE_A1270-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_METPP

Accession

Primary (citable) accession number: A2SF93

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	March 6, 2007
Last modified:	November 16, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program