ID   A2SCL6_METPP            Unreviewed;       571 AA.
AC   A2SCL6;
DT   06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2007, sequence version 1.
DT   27-MAR-2024, entry version 83.
DE   SubName: Full=Putative acetyl-coenzyme A synthetase {ECO:0000313|EMBL:ABM93305.1};
DE            EC=6.2.1.1 {ECO:0000313|EMBL:ABM93305.1};
GN   OrderedLocusNames=Mpe_A0343 {ECO:0000313|EMBL:ABM93305.1};
OS   Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Sphaerotilaceae; Methylibium.
OX   NCBI_TaxID=420662 {ECO:0000313|EMBL:ABM93305.1, ECO:0000313|Proteomes:UP000000366};
RN   [1] {ECO:0000313|EMBL:ABM93305.1, ECO:0000313|Proteomes:UP000000366}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1232 / LMG 22953 / PM1
RC   {ECO:0000313|Proteomes:UP000000366};
RX   PubMed=17158667; DOI=10.1128/JB.01259-06;
RA   Kane S.R., Chakicherla A.Y., Chain P.S.G., Schmidt R., Shin M.W.,
RA   Legler T.C., Scow K.M., Larimer F.W., Lucas S.M., Richardson P.M.,
RA   Hristova K.R.;
RT   "Whole-genome analysis of the methyl tert-butyl ether-degrading beta-
RT   proteobacterium Methylibium petroleiphilum PM1.";
RL   J. Bacteriol. 189:1931-1945(2007).
CC   -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC       {ECO:0000256|ARBA:ARBA00006432}.
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DR   EMBL; CP000555; ABM93305.1; -; Genomic_DNA.
DR   RefSeq; WP_011827944.1; NC_008825.1.
DR   AlphaFoldDB; A2SCL6; -.
DR   STRING; 420662.Mpe_A0343; -.
DR   KEGG; mpt:Mpe_A0343; -.
DR   eggNOG; COG0365; Bacteria.
DR   HOGENOM; CLU_000022_59_10_4; -.
DR   Proteomes; UP000000366; Chromosome.
DR   GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43605:SF10; ACYL-COA SYNTHETASE MEDIUM CHAIN FAMILY MEMBER 3; 1.
DR   PANTHER; PTHR43605; ACYL-COENZYME A SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   3: Inferred from homology;
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ABM93305.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000366}.
FT   DOMAIN          53..393
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          457..535
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   571 AA;  62790 MW;  BDA321EFCD59426F CRC64;
     MTSAVPFLQA RDLLLRLRDD QAAAAREFRW PALGEFNWAL DHFDAMARDP ARADAPALWI
     VGEDGSEVKR SFRELSQRSA QVANHLRALG VRRGDRVLLM LGNELALWET MLAAMKLGAV
     LIPATALLTT EDLRDRMERG DVRHVVTASA QTDKFAPLPG DYTRISIGEA QPGWQRFEDA
     AAAPSAFTPD GPTRASDPLL LYFTSGTTSK PKLVLHTHQS YPVGHLSTMY WIGLRPGDVH
     LNISSPGWAK HAWSCFFAPW NAGACVFIYN TARFNAGGLL AVLERCRVTS LCAPPTVWRM
     MVQEDLGAYR GRLALRELIG AGEPLNPEII EQVRAAWDMT VRDGYGQTET TAQIGNAPGQ
     PLKPGSMGRP LPGYRIALID ADGKEADEGE VCIVLAERPL GLMVGYQDSA EKTADAMRDG
     YYHTGDVAAR DAEGYITFVG RADDVFKASD YRISPFELES ALIEHEAVAE VAVVPSPDPL
     RLAVPKAYLI LTAGQTPDRA LAEAILGFAR KQLAPYKRVR RIEFVTELPK TISGKIRRVQ
     LRAQEVERRA AGVRAAGEFF EEDFPQLKAE A
//