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A2S9Z5 (A2S9Z5_BURM9) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonuclease 3 HAMAP-Rule MF_00104

EC=3.1.26.3 HAMAP-Rule MF_00104
Alternative name(s):
Ribonuclease III HAMAP-Rule MF_00104
Gene names
Name:rnc HAMAP-Rule MF_00104
Ordered Locus Names:BMA10229_A2815 EMBL ABN02752.1
OrganismBurkholderia mallei (strain NCTC 10229) [Complete proteome] [HAMAP] EMBL ABN02752.1
Taxonomic identifier412022 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

Protein attributes

Sequence length467 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104 SAAS SAAS011907

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104 SAAS SAAS011907

Cofactor

Mg2+ By similarity. HAMAP-Rule MF_00104 SAAS SAAS011907

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00104 SAAS SAAS011907

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00104 SAAS SAAS011907.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain. HAMAP-Rule MF_00104

Contains 1 RNase III domain. HAMAP-Rule MF_00104

Contains DRBM (double-stranded RNA-binding) domain. SAAS SAAS011907

Contains RNase III domain. SAAS SAAS011907

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain3 – 125123RNase III By similarity HAMAP-Rule MF_00104
Domain152 – 22271DRBM By similarity HAMAP-Rule MF_00104

Sites

Active site421 By similarity HAMAP-Rule MF_00104
Metal binding381Magnesium By similarity HAMAP-Rule MF_00104
Metal binding1111Magnesium By similarity HAMAP-Rule MF_00104
Metal binding1141Magnesium By similarity HAMAP-Rule MF_00104

Sequences

Sequence LengthMass (Da)Tools
A2S9Z5 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: CF06C8BD4E29459C

FASTA46749,574
        10         20         30         40         50         60 
MPLSQLESRL RYEFRNAELL RQALTHRSHS ATHNERLEFL GDSVLNCAVA ALLFQRFGKL 

        70         80         90        100        110        120 
DEGDLSRVRA NLVKQQSLYE IAQALNISDG LRLGEGELRS GGFRRPSILA DAFEAIIGAV 

       130        140        150        160        170        180 
FLDGGFEAAQ GVIKRLYVPI LDHIDPRTLG KDAKTLLQEY LQGHKIALPT YTVVATHGAA 

       190        200        210        220        230        240 
HNQQFEVECT VPKLDIKVSG SGASRRAAEQ AAAKKALDEV TAVAPMLAAK PKRSKSARGA 

       250        260        270        280        290        300 
KHVEPEIVPG VKGVQEALDL RSPERKERGA NRVAGGEAKG VESKAVDAKH GESRAAQLRA 

       310        320        330        340        350        360 
DDAKAGETKA GEARASADAK AGAHTHAAAM PAVPEQADDA ARSPATTSVA VIRAAHVEHG 

       370        380        390        400        410        420 
LDKGEPRASK PAEKTAAATD KPPEKASDKP SPEKTSEKTP DKSHEKQLDK SSEPVAEKAL 

       430        440        450        460 
DKTADKPDAA ARLPAETADR PPRARDASSS AEPDLAAAPV RVADAGH 

« Hide

References

[1]DeShazer D., Woods D.E., Nierman W.C.
Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCTC 10229 EMBL ABN02752.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000546 Genomic DNA. Translation: ABN02752.1.
RefSeqYP_001028764.1. NC_008836.1.

3D structure databases

ProteinModelPortalA2S9Z5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING412022.BMA10229_A2815.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABN02752; ABN02752; BMA10229_A2815.
GeneID4791109.
KEGGbml:BMA10229_A2815.
PATRIC19136628. VBIBurMal46188_5009.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0571.
HOGENOMHOG000246809.
KOK03685.
OMAMPPSQLE.
OrthoDBEOG6T1WVS.
ProtClustDBPRK14718.

Enzyme and pathway databases

BioCycBMAL412022:GJI8-2815-MONOMER.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR014720. dsRNA-bd_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF14622. Ribonucleas_3_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. SSF69065. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA2S9Z5_BURM9
AccessionPrimary (citable) accession number: A2S9Z5
Entry history
Integrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: April 16, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)