A2S526 (A2S526_BURM9) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase EMBL ABN03492.1

Gene names

Name:	wcbS EMBL ABN03492.1
Ordered Locus Names:	BMA10229_A1060

Organism

Burkholderia mallei (strain NCTC 10229) [Complete proteome] [HAMAP]

Taxonomic identifier

412022 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2S526 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: EED7108512266A71	FASTA	305	33,143
	10 20 30 40 50 60 MSVPTGWATS QGTLARALTI DGHGLHTGRR VGVRILPARP EDGVTGIAFR RVEQGRTLAT 70 80 90 100 110 120 LPVDPALRRA QPLCTMLRNA DGVGVRTVEH LLASLLACEI DHAIVELDAE EVPILDGSAT 130 140 150 160 170 180 PWVDAIRTCG RVALDAPKRF IRVLRTVVVT EGEGEQRREM RIEPAPRYEL SVRNDLRGFG 190 200 210 220 230 240 EMHWDGALTP AAFATEIAPS RSYGRVKWAV PAILAGYLRG MPILRGARPS CTASIVGKRV 250 260 270 280 290 300 LGGMRLPDEF VRHRVLDLVG DLALAGAPLL ARVSAVRPGH EMNFRLVDAL LAEPGAWQWA DFSEA

References

[1]	DeShazer D., Woods D.E., Nierman W.C. Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000546 Genomic DNA. Translation: ABN03492.1.
RefSeq	YP_001027045.1. NC_008836.1.
3D structure databases
ProteinModelPortal	A2S526.
ModBase	Search...
Protein-protein interaction databases
STRING	A2S526.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4792447.
GenomeReviews	Gene locus BMA10229_A1060 in contig CP000546_GR.
KEGG	bml:BMA10229_A1060.
PATRIC	19133072. VBIBurMal46188_3256.
TIGR	BMA10229_A1060.
Phylogenomic databases
HOGENOM	HBG482342.
OMA	IAFRRVA.
PhylomeDB	A2S526.
ProtClustDB	PRK13187.
Family and domain databases
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KO	K02535.
Pfam	PF03331. LpxC. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
ProtoNet	Search...

Entry information

Entry name

A2S526_BURM9

Accession

Primary (citable) accession number: A2S526

Entry history

Integrated into UniProtKB/TrEMBL:	March 6, 2007
Last sequence update:	March 6, 2007
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)