A2S4R9 (KCY_BURM9) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	BMA10229_A0948

Organism

Burkholderia mallei (strain NCTC 10229) [Complete proteome] [HAMAP]

Taxonomic identifier

412022 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	228 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 228	228	Cytidylate kinase HAMAP MF_00238		PRO_1000048197
Regions
	Nucleotide binding	17 – 25	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	A2S4R9 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: 84471B8596B1EBBE	FASTA	228	24,367
	10 20 30 40 50 60 MKSTRPFHPT PVITIDGPTA SGKGTVAALV AAHLGFHLLD SGALYRLAAL ASIRYQVEPD 70 80 90 100 110 120 DADALASLVD GLHITFREGC AQLDGVDVSD EIRAEAVGNR ASAIAVHASV RAALVARQRA 130 140 150 160 170 180 FRKTPGLVAD GRDMGTLIFP DAVLKVFLTA SVEARAARRH KQLMQKGFSA NIDNLLQDLR 190 200 210 220 ERDARDSNRA AAPLKPAADA KPLDTSALTI EQSVEQVLAW YRELGQPA

References

[1]	DeShazer D., Woods D.E., Nierman W.C. Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCTC 10229.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000546 Genomic DNA. Translation: ABN00740.1.
RefSeq	YP_001026938.1. NC_008836.1.
3D structure databases
ProteinModelPortal	A2S4R9.
ModBase	Search...
Protein-protein interaction databases
STRING	A2S4R9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4790859.
GenomeReviews	Gene locus BMA10229_A0948 in contig CP000546_GR.
KEGG	bml:BMA10229_A0948.
PATRIC	19132850. VBIBurMal46188_3147.
TIGR	BMA10229_A0948.
Phylogenomic databases
HOGENOM	HBG354377.
OMA	DIGTVIC.
PhylomeDB	A2S4R9.
ProtClustDB	PRK00023.
Family and domain databases
HAMAP	MF_00238. Cytidyl_kinase_type1. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. Cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_BURM9

Accession

Primary (citable) accession number: A2S4R9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	March 6, 2007
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program