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Protein
Submitted name:

PCM1 protein

Gene

PCM1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
PCM1 proteinImported
Gene namesi
Name:PCM1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33073.

PTM / Processingi

Proteomic databases

PaxDbiA2RUU9.
PRIDEiA2RUU9.

Expressioni

Gene expression databases

GenevisibleiA2RUU9. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000327077.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1317 – 1783467PCM1_CInterPro annotationAdd
BLAST
Domaini1781 – 183353PCM1_CInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili270 – 29324Sequence analysisAdd
BLAST
Coiled coili493 – 53038Sequence analysisAdd
BLAST
Coiled coili652 – 68231Sequence analysisAdd
BLAST
Coiled coili732 – 76938Sequence analysisAdd
BLAST
Coiled coili826 – 85328Sequence analysisAdd
BLAST
Coiled coili989 – 101628Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IEGR. Eukaryota.
ENOG410YNFX. LUCA.
HOGENOMiHOG000115473.
HOVERGENiHBG053890.
KOiK16537.

Family and domain databases

InterProiIPR031446. PCM1_C.
IPR024138. Pericentriolar_Pcm1.
[Graphical view]
PANTHERiPTHR14164. PTHR14164. 1 hit.
PfamiPF15717. PCM1_C. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2RUU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATGGGPFED GMNDQDLPNW SSENVDDRLN NMDWGAQQKK ANRSSEKNKK
60 70 80 90 100
KFGVESDKRV TNDISPESSP GVGRRRTKTP HTFPHSRYMS QMSVPEQAEL
110 120 130 140 150
EKLKQRINFS DLDQRSIGSD SQGRATAANN KRQLSENRKP FNFLPMQINT
160 170 180 190 200
NKSKDASTNP PNRETIGSAQ CKELFASALS NDLLQNCQVS EEDGRGEPAM
210 220 230 240 250
ESSQIVSRLV QIRDYITKAS SMREDLVEKN ERSANVERLT HLIDHLKEQE
260 270 280 290 300
KSYMKFLKKI LARDPQQEPM EEIENLKKQH DLLKRMLQQQ EQLRALQGRQ
310 320 330 340 350
AALLALQHKA EQAIAVMDDS VVAETAGSLS GVSITSELNE ELNDLIQRFH
360 370 380 390 400
NQLRDSQPPA VPDNRRQAES LSLTREVSQS RKPSASERLP DEKVELFSKM
410 420 430 440 450
RVLQEKKQKM DKLLGELHTL RDQHLNNSSS SPQRSVDQRS TSAPSASVGL
460 470 480 490 500
APVVNGESNS LTSSVPYPTA SLVSQNESEN EGHLNPSEKL QKLNEVRKRL
510 520 530 540 550
NELRELVHYY EQTSDMMTDA VNENRKAEET EESEYDSEHE NSEPVTNIRN
560 570 580 590 600
PQVASTWNEV NSHSNAQCVS NNRDGRTVNS NCEINNRSAA NIRALNMPPS
610 620 630 640 650
LADCRYNREG EQEIHVAQGE DDEEEEEAEE EGVSGASLSS HRSSLVDEHP
660 670 680 690 700
EDAEFEQKIN RLMAAKQKLR QLQDLVAMVQ DDDAAQGVIS ASASNLDDFY
710 720 730 740 750
PAEEDTKQNS NNTRGNANKT QKDTGVNEKA REKFYEAKLQ QQQRELKQLQ
760 770 780 790 800
EERKKLIDIQ EKIQALQTAC PDLQLSAASV GNCPTKKYMP AVTSTPTVNQ
810 820 830 840 850
HETSTSKSVF EPEDSSIVDN ELWSEMRRHE MLREELRQRR KQLEALMAEH
860 870 880 890 900
QRRQGLAETA SPVAVSLRSD GSENLCTPQQ SRTEKTMATW GGSTQCALDE
910 920 930 940 950
EGDEDGYLSE GIVRTDEEEE EEQDASSNDN FSVCPSNSVN HNSYNGKETK
960 970 980 990 1000
NRWKNDCPFS ADENYRPLAK TRQQNISMQR QENLRWVSEL SYVEEKEQWQ
1010 1020 1030 1040 1050
EQINQLKKQL DFSVSICQTL MQDQQTLSCL LQTLLTGPYS VMPSNVASPQ
1060 1070 1080 1090 1100
VHFIMHQLNQ CYTQLTWQQN NVQRLKQMLN ELMRQQNQHP EKPGGKERGS
1110 1120 1130 1140 1150
SASHPPSPSL FCPFSFPTQP VNLFNIPGFT NFSSFAPGMN FSPLFPSNFG
1160 1170 1180 1190 1200
DFSQNISTPS EQQQPLAQNS SGKTEYMAFP KPFESSSSIG AEKPRNKKLP
1210 1220 1230 1240 1250
EEEVESSRTP WLYEQEGEVE KPFIKTGFSV SAEKSTSSNR KNQLDTNGRR
1260 1270 1280 1290 1300
RQFDEESLES FSSMPDPVDP TTVTKTFKTR KASAQASLAS KDKTPKSKSK
1310 1320 1330 1340 1350
KRNSTQLKSR VKNIKTGSDF SMFEALRDTI YSEVATLISQ NESRPHFLIE
1360 1370 1380 1390 1400
LFHELQLLNT DYLRQRALYA LQDIVSRHIS ESHEKGENVK SVNSGTWIAS
1410 1420 1430 1440 1450
NSELTPSESL ATTDDETFEK NFERETHKIS EQNDADNASV LSVSSNFEPF
1460 1470 1480 1490 1500
ATDDLGNTVI HLDQALARMR EYERMKTEAE SNSNMRCTCR IIEDGDGAGA
1510 1520 1530 1540 1550
GTTVNNLEET PVIENRSSQQ PVSEVSTIPC PRIDTQQLDR QIKAIMKEVI
1560 1570 1580 1590 1600
PFLKEHMDEV CSSQLLTSVR RMVLTLTQQN DESKEFVKFF HKQLGSILQD
1610 1620 1630 1640 1650
SLAKFAGRKL KDCGEDLLVE ISEVLFNELA FFKLMQDLDN NSITVKQRCK
1660 1670 1680 1690 1700
RKIEATGVIQ SCAKEAKRIL EDHGSPAGEI DDEDKDKDET ETVKQTQTSE
1710 1720 1730 1740 1750
VYDGPKNVRS DISDQEEDEE SEGCPVSINL SKAETQALTN YGSGEDENED
1760 1770 1780 1790 1800
EEMEEFEEGP VDVQTSLQAN TEATEENEHD EQEAESGNIS QKSDEEDFVK
1810 1820 1830 1840 1850
VEDLPLKLTI YSEADLRKEM VEEEQKNHLS GEICEMQTEE LAGNSETLKE

PETVGAQSI
Length:1,859
Mass (Da):209,906
Last modified:March 6, 2007 - v1
Checksum:i707537DEE9210CF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC133052 mRNA. Translation: AAI33053.1.
RefSeqiNP_001302437.1. NM_001315508.1.
NP_006188.3. NM_006197.3.
UniGeneiHs.491148.

Genome annotation databases

GeneIDi5108.
KEGGihsa:5108.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC133052 mRNA. Translation: AAI33053.1.
RefSeqiNP_001302437.1. NM_001315508.1.
NP_006188.3. NM_006197.3.
UniGeneiHs.491148.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000327077.

Proteomic databases

PaxDbiA2RUU9.
PRIDEiA2RUU9.

Protocols and materials databases

DNASUi5108.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5108.
KEGGihsa:5108.

Organism-specific databases

CTDi5108.
PharmGKBiPA33073.

Phylogenomic databases

eggNOGiENOG410IEGR. Eukaryota.
ENOG410YNFX. LUCA.
HOGENOMiHOG000115473.
HOVERGENiHBG053890.
KOiK16537.

Miscellaneous databases

ChiTaRSiPCM1. human.
GenomeRNAii5108.

Gene expression databases

GenevisibleiA2RUU9. HS.

Family and domain databases

InterProiIPR031446. PCM1_C.
IPR024138. Pericentriolar_Pcm1.
[Graphical view]
PANTHERiPTHR14164. PTHR14164. 1 hit.
PfamiPF15717. PCM1_C. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiA2RUU9_HUMAN
AccessioniPrimary (citable) accession number: A2RUU9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: June 8, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.