Unreviewed,
UniProtKB/TrEMBL A2RUF7 (A2RUF7_HUMAN)
Last modified
July 7, 2009.
Version 26.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information
Names and origin
| Protein names | Submitted name: Phosphoinositide-3-kinase, class 2, beta polypeptide EMBL AAI32877.1 Submitted name: Phosphoinositide-3-kinase, class 2, beta polypeptide, isoform CRA_b EMBL EAW91514.1 | ||||
| Gene names |
| ||||
| Organism | Homo sapiens (Human) EMBL AAI32877.1 | ||||
| Taxonomic identifier | 9606 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Protein attributes
| Sequence length | 1634 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Sequence similarities | Contains 1 C2 domain. RuleBase RU003412V0 Contains 1 PI3K/PI4K domain. Spearmint SPM000403 |
Ontologies
| Keywords | |
|---|---|
| Molecular function | Kinase Spearmint SPM000403 Transferase |
| Gene Ontology (GO) | |
| Biological process | phosphoinositide phosphorylation Inferred from electronic annotation. Source: InterPro phosphoinositide-mediated signalingInferred from electronic annotation. Source: InterPro |
| Cellular component | phosphoinositide 3-kinase complex Inferred from electronic annotation. Source: InterPro |
| Molecular function | 1-phosphatidylinositol-3-kinase activity Inferred from electronic annotation. Source: InterPro phosphoinositide bindingInferred from electronic annotation. Source: InterPro protein bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Pooled EMBL AAI32877.1 and Testicle EMBL AAI36646.1. |
| [2] | Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. Venter J.C.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. |
| [3] | Livingston R.J., Rieder M.J., McFarland I.W., da Ponte S.H., Aklestad J., Swanson J., Johnson E., Nickerson D.A. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| BC132876 mRNA. Translation: AAI32877.1. BC136645 mRNA. Translation: AAI36646.1. EU332863 Genomic DNA. Translation: ABY87552.1. CH471067 Genomic DNA. Translation: EAW91514.1. | |
| IPI | IPI00292056. |
| RefSeq | NP_002637.3. |
| UniGene | Hs.497487 |
3D structure databases | |
| ModBase | Search... |
Proteomic databases | |
| PRIDE | A2RUF7. |
Genome annotation databases | |
| Ensembl | ENSG00000133056. Homo sapiens. [Contig view] |
| GeneID | 5287. |
| KEGG | hsa:5287. |
| UCSC | uc001haw.1. human. |
Organism-specific databases | |
| HGNC | HGNC:8972. PIK3C2B. |
| GenAtlas | Search... |
Phylogenomic databases | |
| HOVERGEN | A2RUF7. |
| OMA | A2RUF7. KESLYWL. |
Gene expression databases | |
| Bgee | A2RUF7. |
Family and domain databases | |
| InterPro | IPR000008. C2_Ca-dep. IPR018029. C2_membr_targeting. IPR000403. PI3/4_kinase_cat. IPR018936. PI3/4_kinase_CS. IPR002420. PI3K_C2. IPR000341. PI3K_ras_bd. IPR001263. PI3Ka. IPR015433. PI_Kinase. IPR001683. PX. [Graphical view] |
| Gene3D | G3DSA:1.10.1070.11. PI3/4_kinase_cat. 1 hit. G3DSA:1.25.40.70. PI3Ka. 1 hit. G3DSA:3.30.1520.10. PX. 1 hit. |
| PANTHER | PTHR10048. PI_Kinase. 1 hit. |
| Pfam | PF00168. C2. 1 hit. PF00454. PI3_PI4_kinase. 1 hit. PF00792. PI3K_C2. 1 hit. PF00794. PI3K_rbd. 1 hit. PF00613. PI3Ka. 1 hit. PF00787. PX. 1 hit. [Graphical view] |
| SMART | SM00239. C2. 1 hit. SM00142. PI3K_C2. 1 hit. SM00144. PI3K_rbd. 1 hit. SM00145. PI3Ka. 1 hit. SM00146. PI3Kc. 1 hit. SM00312. PX. 1 hit. [Graphical view] |
| PROSITE | PS50004. C2. 1 hit. PS00915. PI3_4_KINASE_1. 1 hit. PS00916. PI3_4_KINASE_2. 1 hit. PS50290. PI3_4_KINASE_3. 1 hit. PS50195. PX. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | A2RUF7_HUMAN | ||||||||
| Accession | Primary (citable) accession number: A2RUF7 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

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