Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A2RU67

- K1467_HUMAN

UniProt

A2RU67 - K1467_HUMAN

Protein

Uncharacterized protein KIAA1467

Gene

KIAA1467

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (06 Mar 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized protein KIAA1467
    Gene namesi
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 12

    Organism-specific databases

    HGNCiHGNC:29288. KIAA1467.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA128395790.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 622622Uncharacterized protein KIAA1467PRO_0000288913Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei16 – 161Phosphoserine2 Publications
    Modified residuei30 – 301Phosphoserine1 Publication
    Modified residuei33 – 331Phosphoserine2 Publications
    Modified residuei62 – 621Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiA2RU67.
    PaxDbiA2RU67.
    PRIDEiA2RU67.

    PTM databases

    PhosphoSiteiA2RU67.

    Expressioni

    Gene expression databases

    ArrayExpressiA2RU67.
    BgeeiA2RU67.
    CleanExiHS_KIAA1467.
    GenevestigatoriA2RU67.

    Organism-specific databases

    HPAiCAB008385.
    HPA010803.

    Interactioni

    Protein-protein interaction databases

    BioGridi121660. 2 interactions.
    IntActiA2RU67. 1 interaction.
    STRINGi9606.ENSP00000197268.

    Structurei

    3D structure databases

    ProteinModelPortaliA2RU67.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei104 – 12421HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ITFG3 family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG69883.
    HOGENOMiHOG000113167.
    HOVERGENiHBG101158.
    InParanoidiA2RU67.
    OMAiIFVQAQN.
    OrthoDBiEOG783MWS.
    PhylomeDBiA2RU67.
    TreeFamiTF327203.

    Family and domain databases

    Gene3Di2.140.10.10. 2 hits.
    InterProiIPR027295. Quinonprotein_ADH-like_fam.
    IPR011047. Quinonprotein_ADH-like_supfam.
    [Graphical view]
    SUPFAMiSSF50998. SSF50998. 3 hits.

    Sequencei

    Sequence statusi: Complete.

    A2RU67-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATVLSRALK LPGKKSPDLG EYDPLTQADS DESEDDLVLN LQKNGGVKNG    50
    KSPLGEAPEP DSDAEVAEAA KPHLSEVTTE GYPSEPLGGL EQKAASSLVS 100
    YVRTSVFLLT LGISMILVLL CAFLIPCPPR DLHSTWSRHL GSQGGGDLSP 150
    LELADVNGDG LRDVLLSFVM SRNGSAVGVS RPAANLVCLS GMNGSTLWSS 200
    LLPEEARDIT CLELMPGSLA ETICLVTGTH KMLSAFNATS GKAIWTLNPN 250
    YLSNGTLAAP VVVLPDLDED GVRDLVVLAI GELQPDLCFL LVSGRTGNPV 300
    GRPVKYNIVG VGNLIGPQVY ITTNGAVYIL FGFGNIQAVA LRDIFVQAQN 350
    RDSSPPSLQI EEPEWEKRRS INLSELIDVY SDGVELLQMV KAPDSNCSNL 400
    LITTRQSLVL LRGQNLTPYW ALRLQGLRSQ PTPGYFTDDQ TLDFLLQIQD 450
    GVGMKKMMVV DGDSGSIVWS YRAPCHMKET PATSAVTSDQ KSVFLFWAEG 500
    LSAASPNSDI ILGTEPPSLH HLYLLHPAFP SILLDLANTT GTVTASEVGI 550
    NDLWKDAFYV TRTTGPSSEG HPAALVVSKL SLRWALMEGQ MAQLQESTPK 600
    IGRGELRRFL SRIKFVEAPY EI 622
    Length:622
    Mass (Da):67,039
    Last modified:March 6, 2007 - v1
    Checksum:i2C03F481C2FA7DC0
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti59 – 591E → K in BAC86111. (PubMed:14702039)Curated
    Sequence conflicti91 – 911E → K in AAH39267. (PubMed:15489334)Curated
    Sequence conflicti189 – 1891L → P in BAC86111. (PubMed:14702039)Curated
    Sequence conflicti450 – 4501D → N in CAI56785. (PubMed:17974005)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK125278 mRNA. Translation: BAC86111.1.
    CR936647 mRNA. Translation: CAI56785.1.
    BC039267 mRNA. Translation: AAH39267.1.
    BC132772 mRNA. Translation: AAI32773.1.
    BC132774 mRNA. Translation: AAI32775.1.
    AB040900 mRNA. Translation: BAA95991.1.
    CCDSiCCDS31750.1.
    RefSeqiNP_065904.1. NM_020853.1.
    UniGeneiHs.132660.

    Genome annotation databases

    EnsembliENST00000197268; ENSP00000197268; ENSG00000084444.
    ENST00000416494; ENSP00000394063; ENSG00000084444.
    GeneIDi57613.
    KEGGihsa:57613.
    UCSCiuc001rbi.3. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK125278 mRNA. Translation: BAC86111.1 .
    CR936647 mRNA. Translation: CAI56785.1 .
    BC039267 mRNA. Translation: AAH39267.1 .
    BC132772 mRNA. Translation: AAI32773.1 .
    BC132774 mRNA. Translation: AAI32775.1 .
    AB040900 mRNA. Translation: BAA95991.1 .
    CCDSi CCDS31750.1.
    RefSeqi NP_065904.1. NM_020853.1.
    UniGenei Hs.132660.

    3D structure databases

    ProteinModelPortali A2RU67.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 121660. 2 interactions.
    IntActi A2RU67. 1 interaction.
    STRINGi 9606.ENSP00000197268.

    PTM databases

    PhosphoSitei A2RU67.

    Proteomic databases

    MaxQBi A2RU67.
    PaxDbi A2RU67.
    PRIDEi A2RU67.

    Protocols and materials databases

    DNASUi 57613.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000197268 ; ENSP00000197268 ; ENSG00000084444 .
    ENST00000416494 ; ENSP00000394063 ; ENSG00000084444 .
    GeneIDi 57613.
    KEGGi hsa:57613.
    UCSCi uc001rbi.3. human.

    Organism-specific databases

    CTDi 57613.
    GeneCardsi GC12P013197.
    HGNCi HGNC:29288. KIAA1467.
    HPAi CAB008385.
    HPA010803.
    neXtProti NX_A2RU67.
    PharmGKBi PA128395790.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG69883.
    HOGENOMi HOG000113167.
    HOVERGENi HBG101158.
    InParanoidi A2RU67.
    OMAi IFVQAQN.
    OrthoDBi EOG783MWS.
    PhylomeDBi A2RU67.
    TreeFami TF327203.

    Miscellaneous databases

    ChiTaRSi KIAA1467. human.
    GenomeRNAii 57613.
    NextBioi 64268.

    Gene expression databases

    ArrayExpressi A2RU67.
    Bgeei A2RU67.
    CleanExi HS_KIAA1467.
    Genevestigatori A2RU67.

    Family and domain databases

    Gene3Di 2.140.10.10. 2 hits.
    InterProi IPR027295. Quinonprotein_ADH-like_fam.
    IPR011047. Quinonprotein_ADH-like_supfam.
    [Graphical view ]
    SUPFAMi SSF50998. SSF50998. 3 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Amygdala.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Brain.
    4. "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O.
      DNA Res. 7:143-150(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 191-622.
      Tissue: Brain.
    5. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-16; SER-30; SER-33 AND SER-62, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    6. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-16 AND SER-33, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Leukemic T-cell.
    7. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiK1467_HUMAN
    AccessioniPrimary (citable) accession number: A2RU67
    Secondary accession number(s): Q49AF2
    , Q5CZ81, Q6ZUV7, Q9P261
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 29, 2007
    Last sequence update: March 6, 2007
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 12
      Human chromosome 12: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3