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Protein
Submitted name:

Legumain

Gene

Lgmn

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
LegumainImported
Submitted name:
Legumain, isoform CRA_aImported
Gene namesi
Name:LgmnImported
ORF Names:mCG_115373Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1330838. Lgmn.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_501010250818 – 435Sequence analysisAdd BLAST418

Expressioni

Gene expression databases

BgeeiENSMUSG00000021190.
ExpressionAtlasiA2RTI3. baseline and differential.

Structurei

3D structure databases

SMRiA2RTI3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1348. Eukaryota.
COG5206. LUCA.
HOVERGENiHBG031304.
KOiK01369.
OMAiKVMQFQG.
OrthoDBiEOG091G08C5.

Family and domain databases

InterProiView protein in InterPro
IPR001096. Peptidase_C13.
PANTHERiPTHR12000. PTHR12000. 1 hit.
PfamiView protein in Pfam
PF01650. Peptidase_C13. 1 hit.
PIRSFiPIRSF019663. Legumain. 1 hit.
PRINTSiPR00776. HEMOGLOBNASE.

Sequencei

Sequence statusi: Complete.

A2RTI3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTWRVAVLLS LVLGAGAVPV GVDDPEDGGK HWVVIVAGSN GWYNYRHQAD
60 70 80 90 100
ACHAYQIIHR NGIPDEQIIV MMYDDIANSE ENPTPGVVIN RPNGTDVYKG
110 120 130 140 150
VLKDYTGEDV TPENFLAVLR GDAEAVKGKG SGKVLKSGPR DHVFIYFTDH
160 170 180 190 200
GATGILVFPN DDLHVKDLNK TIRYMYEHKM YQKMVFYIEA CESGSMMNHL
210 220 230 240 250
PDDINVYATT AANPKESSYA CYYDEERGTY LGDWYSVNWM EDSDVEDLTK
260 270 280 290 300
ETLHKQYHLV KSHTNTSHVM QYGNKSISTM KVMQFQGMKH RASSPISLPP
310 320 330 340 350
VTHLDLTPSP DVPLTILKRK LLRTNDVKES QNLIGQIQQF LDARHVIEKS
360 370 380 390 400
VHKIVSLLAG FGETAERHLS ERTMLTAHDC YQEAVTHFRT HCFNWHSVTY
410 420 430
EHALRYLYVL ANLCEAPYPI DRIEMAMDKV CLSHY
Length:435
Mass (Da):49,373
Last modified:March 6, 2007 - v1
Checksum:iF956B9E10098013D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC132515 mRNA. Translation: AAI32516.1.
BC132519 mRNA. Translation: AAI32520.1.
CH466549 Genomic DNA. Translation: EDL18865.1.
RefSeqiNP_035305.1. NM_011175.3.
UniGeneiMm.17185.

Genome annotation databases

GeneIDi19141.
KEGGimmu:19141.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA2RTI3_MOUSE
AccessioniPrimary (citable) accession number: A2RTI3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: July 5, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)