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Protein

C-X-C motif chemokine

Gene

Cxcl1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation
Biological processChemotaxisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
C-X-C motif chemokineUniRule annotation
Gene namesi
Name:Cxcl1Imported
ORF Names:mCG_1708Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:108068 Cxcl1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24UniRule annotationAdd BLAST24
ChainiPRO_501420510625 – 96C-X-C motif chemokineUniRule annotationAdd BLAST72

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000029380
ExpressionAtlasiA2RTH0 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiA2RTH0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 90SCYInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the intercrine alpha (chemokine CxC) family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410J3WE Eukaryota
ENOG410ZT1C LUCA
HOVERGENiHBG107789
KOiK05505
OMAiLNCDKSN
OrthoDBiEOG091G14TE

Family and domain databases

CDDicd00273 Chemokine_CXC, 1 hit
InterProiView protein in InterPro
IPR001089 Chemokine_CXC
IPR018048 Chemokine_CXC_CS
IPR001811 Chemokine_IL8-like_dom
IPR033899 CXC_Chemokine_domain
IPR036048 Interleukin_8-like_sf
PANTHERiPTHR10179 PTHR10179, 1 hit
PfamiView protein in Pfam
PF00048 IL8, 1 hit
PRINTSiPR00437 SMALLCYTKCXC
SMARTiView protein in SMART
SM00199 SCY, 1 hit
SUPFAMiSSF54117 SSF54117, 1 hit
PROSITEiView protein in PROSITE
PS00471 SMALL_CYTOKINES_CXC, 1 hit

Sequencei

Sequence statusi: Complete.

A2RTH0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPATRSLLC AALLLLATSR LATGAPIANE LRCQCLQTMA GIHLKNIQSL
60 70 80 90
KVLPSGPHCT QTEVIATLKN GREACLDPEA PLVQKIVQKM LKGVPK
Length:96
Mass (Da):10,254
Last modified:March 6, 2007 - v1
Checksum:i4A52B5E5C38B45C2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC132502 mRNA Translation: AAI32503.1
BC132504 mRNA Translation: AAI32505.1
CH466617 Genomic DNA Translation: EDL05301.1
RefSeqiNP_032202.1, NM_008176.3
UniGeneiMm.21013

Genome annotation databases

GeneIDi14825
KEGGimmu:14825

Similar proteinsi

Entry informationi

Entry nameiA2RTH0_MOUSE
AccessioniPrimary (citable) accession number: A2RTH0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: May 23, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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