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A2RSX2

- A2RSX2_MOUSE

UniProt

A2RSX2 - A2RSX2_MOUSE

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Protein
Submitted name:

Homeobox gene HB9

Gene
Mnx1, Hlxb9, mCG_7342
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. cell morphogenesis involved in neuron differentiation Source: MGI
  2. central nervous system neuron differentiation Source: MGI
  3. diaphragm development Source: MGI
  4. dorsal/ventral neural tube patterning Source: MGI
  5. endocrine pancreas development Source: MGI
  6. motor neuron axon guidance Source: MGI
  7. nerve development Source: MGI
  8. neuron differentiation Source: MGI
  9. neuron migration Source: MGI
  10. neuron projection morphogenesis Source: MGI
  11. pancreas development Source: MGI
  12. post-embryonic development Source: MGI
  13. respiratory system development Source: MGI
  14. spinal cord motor neuron cell fate specification Source: MGI
Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotationsImported

Names & Taxonomyi

Protein namesi
Submitted name:
Homeobox gene HB9Imported
Submitted name:
Motor neuron and pancreas homeobox 1Imported
Submitted name:
Motor neuron and pancreas homeobox protein 1Imported
Gene namesi
Name:Mnx1Imported
Synonyms:Hlxb9Imported
ORF Names:mCG_7342Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 5

Organism-specific databases

MGIiMGI:109160. Mnx1.

Subcellular locationi

Nucleus By similarity UniRule annotation

GO - Cellular componenti

  1. nucleus Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotations

Expressioni

Gene expression databases

GenevestigatoriA2RSX2.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000001608.

Family & Domainsi

Sequence similaritiesi

Contains homeobox DNA-binding domain.SAAS annotations

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotationsImported

Phylogenomic databases

GeneTreeiENSGT00750000117598.
HOVERGENiHBG051910.
InParanoidiA2RSX2.
KOiK08025.
OMAiYNSSDCS.
OrthoDBiEOG7VHT0H.
TreeFamiTF351530.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00024. HOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2RSX2-1 [UniParc]FASTAAdd to Basket

« Hide

MEKSKNFRID ALLAVDPPRA ASTQSAPLAL VTSLATTVSG PGRGGSGGGG    50
TSSGASRSCS PASSEATAAP GDRLRAESPS PPRLLAAHCA LLPKPGFLGA 100
GGGGGAAGGP GTPHHHAHPG AAAAAAAAAA AAAAGGLALG LHPGGAQGGA 150
GLPAQAALYG HPVYSYSAAA AAAALAGQHP ALSYSYPQVQ GAHPAHPADP 200
IKLGASTFQL DQWLRASTAG MILPKMPDFS SQAQSNLLGK CRRPRTAFTS 250
QQLLELEHQF KLNKYLSRPK RFEVATSLML TETQVKIWFQ NRRMKWKRSK 300
KAKEQAAQEA EKQKGGGGGT GKGGSEEKTE EELMGPPVSG DKASGRRLRD 350
LRDSDPDEDE DDEEEDNFPY SNGAGAHAAS SDCSSEDDSP PPRLGGPGHQ 400
PLPQ 404
Length:404
Mass (Da):41,314
Last modified:March 6, 2007 - v1
Checksum:i18FB4AA7D9B345DB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC164700 Genomic DNA. No translation available.
BC132283 mRNA. Translation: AAI32284.1.
CH466524 Genomic DNA. Translation: EDL37244.1.
RefSeqiNP_064328.2. NM_019944.2.
UniGeneiMm.103760.

Genome annotation databases

EnsembliENSMUST00000165512; ENSMUSP00000129503; ENSMUSG00000001566.
GeneIDi15285.
KEGGimmu:15285.
UCSCiuc008wuk.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC164700 Genomic DNA. No translation available.
BC132283 mRNA. Translation: AAI32284.1 .
CH466524 Genomic DNA. Translation: EDL37244.1 .
RefSeqi NP_064328.2. NM_019944.2.
UniGenei Mm.103760.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000001608.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000165512 ; ENSMUSP00000129503 ; ENSMUSG00000001566 .
GeneIDi 15285.
KEGGi mmu:15285.
UCSCi uc008wuk.2. mouse.

Organism-specific databases

CTDi 3110.
MGIi MGI:109160. Mnx1.

Phylogenomic databases

GeneTreei ENSGT00750000117598.
HOVERGENi HBG051910.
InParanoidi A2RSX2.
KOi K08025.
OMAi YNSSDCS.
OrthoDBi EOG7VHT0H.
TreeFami TF351530.

Miscellaneous databases

NextBioi 287923.
SOURCEi Search...

Gene expression databases

Genevestigatori A2RSX2.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
InterProi IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view ]
Pfami PF00046. Homeobox. 1 hit.
[Graphical view ]
PRINTSi PR00024. HOMEOBOX.
SMARTi SM00389. HOX. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
PROSITEi PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  3. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  5. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2RSX2_MOUSE
AccessioniPrimary (citable) accession number: A2RSX2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: April 16, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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