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Protein
Submitted name:

V-crk sarcoma virus CT10 oncogene homolog (Avian)-like

Gene

Crkl

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
V-crk sarcoma virus CT10 oncogene homolog (Avian)-likeImported
Gene namesi
Name:CrklImported
ORF Names:mCG_131167Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:104686. Crkl.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSMUSG00000006134.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000006293.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 102SH2InterPro annotationAdd BLAST89
Domaini123 – 183SH3InterPro annotationAdd BLAST61

Keywords - Domaini

SH3 domainSAAS annotation

Phylogenomic databases

eggNOGiKOG4792. Eukaryota.
ENOG4110574. LUCA.
HOVERGENiHBG105616.
KOiK04438.
OMAiTRMNISG.
OrthoDBiEOG091G0JPQ.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiView protein in InterPro
IPR000980. SH2.
IPR011511. SH3_2.
IPR001452. SH3_domain.
PfamiView protein in Pfam
PF00017. SH2. 1 hit.
PF00018. SH3_1. 1 hit.
PF07653. SH3_2. 1 hit.
PRINTSiPR00401. SH2DOMAIN.
PR00452. SH3DOMAIN.
SMARTiView protein in SMART
SM00252. SH2. 1 hit.
SM00326. SH3. 2 hits.
SUPFAMiSSF50044. SSF50044. 2 hits.
SSF55550. SSF55550. 2 hits.
PROSITEiView protein in PROSITE
PS50001. SH2. 1 hit.
PS50002. SH3. 1 hit.

Sequencei

Sequence statusi: Complete.

A2RS58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSARFDSSD RSAWYMGPVT RQEAQTRLQG QRHGMFLVRD SSTCPGDYVL
60 70 80 90 100
SVSENSRVSH YIINSLPNRR FKIGDQEFDH LPALLEFYKI HYLDTTTLIE
110 120 130 140 150
PAPRYPSPPV GSVSAPNLPT AEENLEYVRT LYDFPGNDAE DLPFKKGELL
160 170 180 190 200
VIIEKPEEQW WSARNKDGRV GMIPVPYVEK LVRSSPHGKH GNRNSNSYGI
210 220 230 240 250
PEPAHAYAQP QTTTPLPTVA STPGAAINPL PSTQNGPVFA KAIQKRVPCA
260 270 280 290 300
YDKTALALEV GDIVKVTRMN INGQWEGEVN GRKGLFPFTH VKIFDPQNPD

DNE
Length:303
Mass (Da):33,830
Last modified:March 6, 2007 - v1
Checksum:iA8C801F78EF73573
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC131984 mRNA. Translation: AAI31985.1.
BC131986 mRNA. Translation: AAI31987.1.
CH466521 Genomic DNA. Translation: EDK97459.1.
RefSeqiNP_031790.2. NM_007764.5.
UniGeneiMm.21048.
Mm.451241.
Mm.486420.

Genome annotation databases

GeneIDi12929.
KEGGimmu:12929.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC131984 mRNA. Translation: AAI31985.1.
BC131986 mRNA. Translation: AAI31987.1.
CH466521 Genomic DNA. Translation: EDK97459.1.
RefSeqiNP_031790.2. NM_007764.5.
UniGeneiMm.21048.
Mm.451241.
Mm.486420.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000006293.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi12929.
KEGGimmu:12929.

Organism-specific databases

CTDi1399.
MGIiMGI:104686. Crkl.

Phylogenomic databases

eggNOGiKOG4792. Eukaryota.
ENOG4110574. LUCA.
HOVERGENiHBG105616.
KOiK04438.
OMAiTRMNISG.
OrthoDBiEOG091G0JPQ.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000006134.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiView protein in InterPro
IPR000980. SH2.
IPR011511. SH3_2.
IPR001452. SH3_domain.
PfamiView protein in Pfam
PF00017. SH2. 1 hit.
PF00018. SH3_1. 1 hit.
PF07653. SH3_2. 1 hit.
PRINTSiPR00401. SH2DOMAIN.
PR00452. SH3DOMAIN.
SMARTiView protein in SMART
SM00252. SH2. 1 hit.
SM00326. SH3. 2 hits.
SUPFAMiSSF50044. SSF50044. 2 hits.
SSF55550. SSF55550. 2 hits.
PROSITEiView protein in PROSITE
PS50001. SH2. 1 hit.
PS50002. SH3. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA2RS58_MOUSE
AccessioniPrimary (citable) accession number: A2RS58
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: February 15, 2017
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.