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A2RRP1

- NBAS_HUMAN

UniProt

A2RRP1 - NBAS_HUMAN

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Protein
Neuroblastoma-amplified sequence
Gene
NBAS, NAG
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Source: UniProt
  2. nuclear-transcribed mRNA catabolic process Source: UniProt
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Neuroblastoma-amplified sequence
Alternative name(s):
Neuroblastoma-amplified gene protein
Gene namesi
Name:NBAS
Synonyms:NAG
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:15625. NBAS.

Subcellular locationi

Cytoplasm 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Involvement in diseasei

Short stature, optic nerve atrophy, and Pelger-Huet anomaly (SOPH) [MIM:614800]: An autosomal recessive syndrome characterized by severe postnatal growth retardation, facial dysmorphism with senile face, small hands and feet, normal intelligence, abnormal nuclear shape in neutrophil granulocytes (Pelger-Huet anomaly), and optic atrophy with loss of visual acuity and color vision.
Note: The disease is caused by mutations affecting the gene represented in this entry.1 Publication
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti1914 – 19141R → H in SOPH. 1 Publication
VAR_068957

Keywords - Diseasei

Disease mutation, Dwarfism

Organism-specific databases

MIMi614800. phenotype.
Orphaneti391677. Short stature-optic atrophy-Pelger-Huet anomaly syndrome.
PharmGKBiPA164723457.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 23712371Neuroblastoma-amplified sequence
PRO_0000292806Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei473 – 4731Phosphoserine3 Publications
Modified residuei475 – 4751Phosphoserine3 Publications
Modified residuei1057 – 10571N6-acetyllysine1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiA2RRP1.
PaxDbiA2RRP1.
PeptideAtlasiA2RRP1.
PRIDEiA2RRP1.

PTM databases

PhosphoSiteiA2RRP1.

Expressioni

Tissue specificityi

Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Well expressed in retinal ganglion cells, epidermal skin cells, and leukocytes. Up-regulated together with N-myc in some neuroblastoma cell lines.4 Publications

Gene expression databases

ArrayExpressiA2RRP1.
BgeeiA2RRP1.
GenevestigatoriA2RRP1.

Organism-specific databases

HPAiHPA036817.

Interactioni

Protein-protein interaction databases

BioGridi119627. 2 interactions.
DIPiDIP-56726N.
IntActiA2RRP1. 3 interactions.
MINTiMINT-4838513.
STRINGi9606.ENSP00000281513.

Structurei

3D structure databases

ProteinModelPortaliA2RRP1.
SMRiA2RRP1. Positions 319-349.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati130 – 16940WD 1
Add
BLAST
Repeati316 – 35540WD 2
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi1421 – 14255Poly-Thr
Compositional biasi2242 – 22476Poly-Leu

Sequence similaritiesi

Contains 2 WD repeats.

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiNOG293605.
HOGENOMiHOG000113737.
InParanoidiA2RRP1.
OMAiIDVNWWA.
OrthoDBiEOG7C5M7C.
PhylomeDBiA2RRP1.
TreeFamiTF313901.

Family and domain databases

Gene3Di2.130.10.10. 3 hits.
InterProiIPR029145. NBAS_N.
IPR011044. Quino_amine_DH_bsu.
IPR013244. Sec39.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamiPF15492. Nbas_N. 1 hit.
PF08314. Sec39. 1 hit.
[Graphical view]
SUPFAMiSSF50969. SSF50969. 2 hits.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: A2RRP1-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MAAPESGPAL SPGTAEGEEE TILYDLLVNT EWPPETEVQP RGNQKHGASF     50
IITKAIRDRL LFLRQYIWYS PAPFLLPDGL VRLVNKQINW HLVLASNGKL 100
LAAVQDQCVE IRSAKDDFTS IIGKCQVPKD PKPQWRRVAW SYDCTLLAYA 150
ESTGTVRVFD LMGSELFVIS PASSFIGDLS YAIAGLIFLE YKASAQWSAE 200
LLVINYRGEL RSYLVSVGTN QSYQESHCFS FSSHYPHGIN TAIYHPGHRL 250
LLVGGCETAE VGMSKASSCG LSAWRVLSGS PYYKQVTNGG DGVTAVPKTL 300
GLLRMLSVKF YSRQGQEQDG IFKMSLSPDG MLLAAIHFSG KLSIWAIPSL 350
KQQGEWGQNE QPGYDDLNPD WRLSTEKRKK IKDKESFYPL IDVNWWADSA 400
VTLARCSGAL TVSSVKTLKN LLGKSCEWFE PSPQVTATHD GGFLSLECEI 450
KLAPKRSRLE TRAGEEDEGE EDSDSDYEIS AKARYFGYIK QGLYLVTEME 500
RFAPPRKRPR TITKNYRLVS LRSTTPEELY QRKIESEEYE EALSLAHTYG 550
LDTDLVYQRQ WRKSAVNVAS IQNYLSKIKK RSWVLHECLE RVPENVDAAK 600
ELLQYGLKGT DLEALLAIGK GADDGRFTLP GEIDIDSISY EELSPPDEEP 650
AKNKKEKELK KRQELLKLVN FSKLTLEQKE LCRCRRKLLT YLDRLATYEE 700
ILGVPHASEQ RYDAEFFKKF RNQNIVLSAR TYAQESNVQA LEILFTYHGS 750
DLLPHRLAIL SNFPETTSPH EYSVLLPEAC FNGDSLMIIP WHEHKHRAKD 800
WCEELACRMV VEPNLQDESE FLYAAQPELL RFRMTQLTVE KVMDWYQTRA 850
EEIEHYARQV DCALSLIRLG MERNIPGLLV LCDNLVTLET LVYEARCDVT 900
LTLKELQQMK DIEKLRLLMN SCSEDKYVTS AYQWMVPFLH RCEKQSPGVA 950
NELLKEYLVT LAKGDLKFPL KIFQHSKPDL QQKIIPDQDQ LMAIALECIY 1000
TCERNDQLCL CYDLLECLPE RGYGDKTEAT TKLHDMVDQL EQILSVSELL 1050
EKHGLEKPIS FVKNTQSSSE EARKLMVRLT RHTGRKQPPV SESHWRTLLQ 1100
DMLTMQQNVY TCLDSDACYE IFTESLLCSS RLENIHLAGQ MMHCSACSEN 1150
PPAGIAHKGK PHYRVSYEKS IDLVLAASRE YFNSSTNLTD SCMDLARCCL 1200
QLITDRPPAI QEELDLIQAV GCLEEFGVKI LPLQVRLCPD RISLIKECIS 1250
QSPTCYKQST KLLGLAELLR VAGENPEERR GQVLILLVEQ ALRFHDYKAA 1300
SMHCQELMAT GYPKSWDVCS QLGQSEGYQD LATRQELMAF ALTHCPPSSI 1350
ELLLAASSSL QTEILYQRVN FQIHHEGGEN ISASPLTSKA VQEDEVGVPG 1400
SNSADLLRWT TATTMKVLSN TTTTTKAVLQ AVSDGQWWKK SLTYLRPLQG 1450
QKCGGAYQIG TTANEDLEKQ GCHPFYESVI SNPFVAESEG TYDTYQHVPV 1500
ESFAEVLLRT GKLAEAKNKG EVFPTTEVLL QLASEALPND MTLALAYLLA 1550
LPQVLDANRC FEKQSPSALS LQLAAYYYSL QIYARLAPCF RDKCHPLYRA 1600
DPKELIKMVT RHVTRHEHEA WPEDLISLTK QLHCYNERLL DFTQAQILQG 1650
LRKGVDVQRF TADDQYKRET ILGLAETLEE SVYSIAISLA QRYSVSRWEV 1700
FMTHLEFLFT DSGLSTLEIE NRAQDLHLFE TLKTDPEAFH QHMVKYIYPT 1750
IGGFDHERLQ YYFTLLENCG CADLGNCAIK PETHIRLLKK FKVVASGLNY 1800
KKLTDENMSP LEALEPVLSS QNILSISKLV PKIPEKDGQM LSPSSLYTIW 1850
LQKLFWTGDP HLIKQVPGSS PEWLHAYDVC MKYFDRLHPG DLITVVDAVT 1900
FSPKAVTKLS VEARKEMTRK AIKTVKHFIE KPRKRNSEDE AQEAKDSKVT 1950
YADTLNHLEK SLAHLETLSH SFILSLKNSE QETLQKYSHL YDLSRSEKEK 2000
LHDEAVAICL DGQPLAMIQQ LLEVAVGPLD ISPKDIVQSA IMKIISALSG 2050
GSADLGGPRD PLKVLEGVVA AVHASVDKGE ELVSPEDLLE WLRPFCADDA 2100
WPVRPRIHVL QILGQSFHLT EEDSKLLVFF RTEAILKASW PQRQVDIADI 2150
ENEENRYCLF MELLESSHHE AEFQHLVLLL QAWPPMKSEY VITNNPWVRL 2200
ATVMLTRCTM ENKEGLGNEV LKMCRSLYNT KQMLPAEGVK ELCLLLLNQS 2250
LLLPSLKLLL ESRDEHLHEM ALEQITAVTT VNDSNCDQEL LSLLLDAKLL 2300
VKCVSTPFYP RIVDHLLASL QQGRWDAEEL GRHLREAGHE AEAGSLLLAV 2350
RGTHQAFRTF STALRAAQHW V 2371
Length:2,371
Mass (Da):268,571
Last modified:March 3, 2009 - v2
Checksum:i54500EFAA487FB94
GO
Isoform 2 (identifier: A2RRP1-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     860-979: Missing.

Note: No experimental confirmation available.

Show »
Length:2,251
Mass (Da):254,816
Checksum:iC253AF9620FDA14E
GO

Sequence cautioni

The sequence AAD18133.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
The sequence CAB43382.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
The sequence AAD18133.1 differs from that shown. Reason: Erroneous termination at position 2372. Translated as stop.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti44 – 441Q → E.1 Publication
Corresponds to variant rs77081203 [ dbSNP | Ensembl ].
VAR_068954
Natural varianti243 – 2431I → V.1 Publication
Corresponds to variant rs13029846 [ dbSNP | Ensembl ].
VAR_057611
Natural varianti655 – 6551K → R.2 Publications
Corresponds to variant rs4668909 [ dbSNP | Ensembl ].
VAR_057612
Natural varianti949 – 9491V → L.1 Publication
Corresponds to variant rs74727069 [ dbSNP | Ensembl ].
VAR_068955
Natural varianti1004 – 10041R → Q.
Corresponds to variant rs16862653 [ dbSNP | Ensembl ].
VAR_057613
Natural varianti1009 – 10091C → S.1 Publication
Corresponds to variant rs74411619 [ dbSNP | Ensembl ].
VAR_068956
Natural varianti1178 – 11781S → N.
Corresponds to variant rs35770368 [ dbSNP | Ensembl ].
VAR_057614
Natural varianti1914 – 19141R → H in SOPH. 1 Publication
VAR_068957
Natural varianti2074 – 20741A → T.1 Publication
Corresponds to variant rs6710817 [ dbSNP | Ensembl ].
VAR_057615

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei860 – 979120Missing in isoform 2.
VSP_026445Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti22 – 221I → T in AAM93544. 1 Publication
Sequence conflicti533 – 5331K → E in AAM93544. 1 Publication
Sequence conflicti745 – 7451F → L in AAM93544. 1 Publication
Sequence conflicti1102 – 11021M → T in AAM93544. 1 Publication
Sequence conflicti1229 – 12291K → E in AAD18133. 1 Publication
Sequence conflicti1277 – 12771E → G in AAM93544. 1 Publication
Sequence conflicti1784 – 17841H → Y in AAM93544. 1 Publication
Sequence conflicti1797 – 17971G → S in AAM93544. 1 Publication
Sequence conflicti1854 – 18541L → S in AAM93544. 1 Publication
Sequence conflicti1997 – 19971E → D in AAD18133. 1 Publication
Sequence conflicti2028 – 20281P → L in AAD18133. 1 Publication
Sequence conflicti2030 – 20301D → N in AAD18133. 1 Publication
Sequence conflicti2033 – 20331P → T in AAD18133. 1 Publication
Sequence conflicti2171 – 21711A → T in AAD18133. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF388385 mRNA. Translation: AAM93544.1.
AC007738 Genomic DNA. No translation available.
AC074184 Genomic DNA. No translation available.
AC008278 Genomic DNA. No translation available.
AC008282 Genomic DNA. Translation: AAY24347.1.
BC051792 mRNA. Translation: AAH51792.2.
BC108693 mRNA. Translation: AAI08694.1. Different termination.
BC131735 mRNA. Translation: AAI31736.1.
AF056195 mRNA. Translation: AAD18133.1. Sequence problems.
AL050281 mRNA. Translation: CAB43382.1. Different initiation.
CCDSiCCDS1685.1. [A2RRP1-1]
PIRiT13150.
RefSeqiNP_056993.2. NM_015909.3. [A2RRP1-1]
UniGeneiHs.467759.

Genome annotation databases

EnsembliENST00000281513; ENSP00000281513; ENSG00000151779. [A2RRP1-1]
ENST00000441750; ENSP00000413201; ENSG00000151779. [A2RRP1-2]
GeneIDi51594.
KEGGihsa:51594.
UCSCiuc002rcc.2. human. [A2RRP1-1]
uc010exl.1. human. [A2RRP1-2]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF388385 mRNA. Translation: AAM93544.1 .
AC007738 Genomic DNA. No translation available.
AC074184 Genomic DNA. No translation available.
AC008278 Genomic DNA. No translation available.
AC008282 Genomic DNA. Translation: AAY24347.1 .
BC051792 mRNA. Translation: AAH51792.2 .
BC108693 mRNA. Translation: AAI08694.1 . Different termination.
BC131735 mRNA. Translation: AAI31736.1 .
AF056195 mRNA. Translation: AAD18133.1 . Sequence problems.
AL050281 mRNA. Translation: CAB43382.1 . Different initiation.
CCDSi CCDS1685.1. [A2RRP1-1 ]
PIRi T13150.
RefSeqi NP_056993.2. NM_015909.3. [A2RRP1-1 ]
UniGenei Hs.467759.

3D structure databases

ProteinModelPortali A2RRP1.
SMRi A2RRP1. Positions 319-349.
ModBasei Search...

Protein-protein interaction databases

BioGridi 119627. 2 interactions.
DIPi DIP-56726N.
IntActi A2RRP1. 3 interactions.
MINTi MINT-4838513.
STRINGi 9606.ENSP00000281513.

PTM databases

PhosphoSitei A2RRP1.

Proteomic databases

MaxQBi A2RRP1.
PaxDbi A2RRP1.
PeptideAtlasi A2RRP1.
PRIDEi A2RRP1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000281513 ; ENSP00000281513 ; ENSG00000151779 . [A2RRP1-1 ]
ENST00000441750 ; ENSP00000413201 ; ENSG00000151779 . [A2RRP1-2 ]
GeneIDi 51594.
KEGGi hsa:51594.
UCSCi uc002rcc.2. human. [A2RRP1-1 ]
uc010exl.1. human. [A2RRP1-2 ]

Organism-specific databases

CTDi 51594.
GeneCardsi GC02M015224.
H-InvDB HIX0001840.
HGNCi HGNC:15625. NBAS.
HPAi HPA036817.
MIMi 608025. gene.
614800. phenotype.
neXtProti NX_A2RRP1.
Orphaneti 391677. Short stature-optic atrophy-Pelger-Huet anomaly syndrome.
PharmGKBi PA164723457.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG293605.
HOGENOMi HOG000113737.
InParanoidi A2RRP1.
OMAi IDVNWWA.
OrthoDBi EOG7C5M7C.
PhylomeDBi A2RRP1.
TreeFami TF313901.

Miscellaneous databases

ChiTaRSi NBAS. human.
GenomeRNAii 51594.
NextBioi 55444.
PROi A2RRP1.
SOURCEi Search...

Gene expression databases

ArrayExpressi A2RRP1.
Bgeei A2RRP1.
Genevestigatori A2RRP1.

Family and domain databases

Gene3Di 2.130.10.10. 3 hits.
InterProi IPR029145. NBAS_N.
IPR011044. Quino_amine_DH_bsu.
IPR013244. Sec39.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view ]
Pfami PF15492. Nbas_N. 1 hit.
PF08314. Sec39. 1 hit.
[Graphical view ]
SUPFAMi SSF50969. SSF50969. 2 hits.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The neuroblastoma amplified gene, NAG: genomic structure and characterisation of the 7.3 kb transcript predominantly expressed in neuroblastoma."
    Scott D.K., Board J.R., Lu X., Pearson A.D.J., Kenyon R.M., Lunec J.
    Gene 307:1-11(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT ARG-655, TISSUE SPECIFICITY.
    Tissue: Neuroblastoma.
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANTS VAL-243 AND ARG-655.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 834-2371 (ISOFORM 2), VARIANT THR-2074.
    Tissue: Eye and PNS.
  4. "Co-amplification of a novel gene, NAG, with the N-myc gene in neuroblastoma."
    Wimmer K., Zhu X.X., Lamb B.J., Kuick R., Ambros P.F., Kovar H., Thoraval D., Motyka S., Alberts J.R., Hanash S.M.
    Oncogene 18:233-238(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 993-2371 (ISOFORMS 1/2), TISSUE SPECIFICITY.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1068-2371 (ISOFORMS 1/2).
    Tissue: Uterus.
  6. "Gene amplification in PNETs/medulloblastomas: mapping of a novel amplified gene within the MYCN amplicon."
    Fruehwald M.C., O'Dorisio M.S., Rush L.J., Reiter J.L., Smiraglia D.J., Wenger G., Costello J.F., White P.S., Krahe R., Brodeur G.M., Plass C.
    J. Med. Genet. 37:501-509(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.
  7. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-473 AND SER-475, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  8. "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
    Han G., Ye M., Zhou H., Jiang X., Feng S., Jiang X., Tian R., Wan D., Zou H., Gu J.
    Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.
  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-473 AND SER-475, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  11. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
    Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
    Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-1057, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  12. "Neuroblastoma amplified sequence gene is associated with a novel short stature syndrome characterised by optic nerve atrophy and Pelger-Huet anomaly."
    Maksimova N., Hara K., Nikolaeva I., Chun-Feng T., Usui T., Takagi M., Nishihira Y., Miyashita A., Fujiwara H., Oyama T., Nogovicina A., Sukhomyasova A., Potapova S., Kuwano R., Takahashi H., Nishizawa M., Onodera O.
    J. Med. Genet. 47:538-548(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION, TISSUE SPECIFICITY, VARIANT SOPH HIS-1914, VARIANTS GLU-44; LEU-949 AND SER-1009.
  13. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  14. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-473 AND SER-475, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiNBAS_HUMAN
AccessioniPrimary (citable) accession number: A2RRP1
Secondary accession number(s): O95790
, Q2VPJ7, Q53TK6, Q86V39, Q8NFY8, Q9Y3W5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: March 3, 2009
Last modified: July 9, 2014
This is version 67 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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