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A2RRP1 (NBAS_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Neuroblastoma-amplified sequence
Alternative name(s):
Neuroblastoma-amplified gene protein
Gene names
Name:NBAS
Synonyms:NAG
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length2371 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Cytoplasm Ref.12.

Tissue specificity

Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Well expressed in retinal ganglion cells, epidermal skin cells, and leukocytes. Up-regulated together with N-myc in some neuroblastoma cell lines. Ref.1 Ref.4 Ref.6 Ref.12

Involvement in disease

Short stature, optic nerve atrophy, and Pelger-Huet anomaly (SOPH) [MIM:614800]: An autosomal recessive syndrome characterized by severe postnatal growth retardation, facial dysmorphism with senile face, small hands and feet, normal intelligence, abnormal nuclear shape in neutrophil granulocytes (Pelger-Huet anomaly), and optic atrophy with loss of visual acuity and color vision.
Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.12

Sequence similarities

Contains 2 WD repeats.

Sequence caution

The sequence AAD18133.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

The sequence AAD18133.1 differs from that shown. Reason: Erroneous termination at position 2372. Translated as stop.

The sequence CAB43382.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: A2RRP1-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: A2RRP1-2)

The sequence of this isoform differs from the canonical sequence as follows:
     860-979: Missing.
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 23712371Neuroblastoma-amplified sequence
PRO_0000292806

Regions

Repeat130 – 16940WD 1
Repeat316 – 35540WD 2
Compositional bias1421 – 14255Poly-Thr
Compositional bias2242 – 22476Poly-Leu

Amino acid modifications

Modified residue4731Phosphoserine Ref.7 Ref.10 Ref.14
Modified residue4751Phosphoserine Ref.7 Ref.10 Ref.14
Modified residue10571N6-acetyllysine Ref.11

Natural variations

Alternative sequence860 – 979120Missing in isoform 2.
VSP_026445
Natural variant441Q → E. Ref.12
Corresponds to variant rs77081203 [ dbSNP | Ensembl ].
VAR_068954
Natural variant2431I → V. Ref.2
Corresponds to variant rs13029846 [ dbSNP | Ensembl ].
VAR_057611
Natural variant6551K → R. Ref.1 Ref.2
Corresponds to variant rs4668909 [ dbSNP | Ensembl ].
VAR_057612
Natural variant9491V → L. Ref.12
Corresponds to variant rs74727069 [ dbSNP | Ensembl ].
VAR_068955
Natural variant10041R → Q.
Corresponds to variant rs16862653 [ dbSNP | Ensembl ].
VAR_057613
Natural variant10091C → S. Ref.12
Corresponds to variant rs74411619 [ dbSNP | Ensembl ].
VAR_068956
Natural variant11781S → N.
Corresponds to variant rs35770368 [ dbSNP | Ensembl ].
VAR_057614
Natural variant19141R → H in SOPH. Ref.12
VAR_068957
Natural variant20741A → T. Ref.3
Corresponds to variant rs6710817 [ dbSNP | Ensembl ].
VAR_057615

Experimental info

Sequence conflict221I → T in AAM93544. Ref.1
Sequence conflict5331K → E in AAM93544. Ref.1
Sequence conflict7451F → L in AAM93544. Ref.1
Sequence conflict11021M → T in AAM93544. Ref.1
Sequence conflict12291K → E in AAD18133. Ref.4
Sequence conflict12771E → G in AAM93544. Ref.1
Sequence conflict17841H → Y in AAM93544. Ref.1
Sequence conflict17971G → S in AAM93544. Ref.1
Sequence conflict18541L → S in AAM93544. Ref.1
Sequence conflict19971E → D in AAD18133. Ref.4
Sequence conflict20281P → L in AAD18133. Ref.4
Sequence conflict20301D → N in AAD18133. Ref.4
Sequence conflict20331P → T in AAD18133. Ref.4
Sequence conflict21711A → T in AAD18133. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified March 3, 2009. Version 2.
Checksum: 54500EFAA487FB94

FASTA2,371268,571
        10         20         30         40         50         60 
MAAPESGPAL SPGTAEGEEE TILYDLLVNT EWPPETEVQP RGNQKHGASF IITKAIRDRL 

        70         80         90        100        110        120 
LFLRQYIWYS PAPFLLPDGL VRLVNKQINW HLVLASNGKL LAAVQDQCVE IRSAKDDFTS 

       130        140        150        160        170        180 
IIGKCQVPKD PKPQWRRVAW SYDCTLLAYA ESTGTVRVFD LMGSELFVIS PASSFIGDLS 

       190        200        210        220        230        240 
YAIAGLIFLE YKASAQWSAE LLVINYRGEL RSYLVSVGTN QSYQESHCFS FSSHYPHGIN 

       250        260        270        280        290        300 
TAIYHPGHRL LLVGGCETAE VGMSKASSCG LSAWRVLSGS PYYKQVTNGG DGVTAVPKTL 

       310        320        330        340        350        360 
GLLRMLSVKF YSRQGQEQDG IFKMSLSPDG MLLAAIHFSG KLSIWAIPSL KQQGEWGQNE 

       370        380        390        400        410        420 
QPGYDDLNPD WRLSTEKRKK IKDKESFYPL IDVNWWADSA VTLARCSGAL TVSSVKTLKN 

       430        440        450        460        470        480 
LLGKSCEWFE PSPQVTATHD GGFLSLECEI KLAPKRSRLE TRAGEEDEGE EDSDSDYEIS 

       490        500        510        520        530        540 
AKARYFGYIK QGLYLVTEME RFAPPRKRPR TITKNYRLVS LRSTTPEELY QRKIESEEYE 

       550        560        570        580        590        600 
EALSLAHTYG LDTDLVYQRQ WRKSAVNVAS IQNYLSKIKK RSWVLHECLE RVPENVDAAK 

       610        620        630        640        650        660 
ELLQYGLKGT DLEALLAIGK GADDGRFTLP GEIDIDSISY EELSPPDEEP AKNKKEKELK 

       670        680        690        700        710        720 
KRQELLKLVN FSKLTLEQKE LCRCRRKLLT YLDRLATYEE ILGVPHASEQ RYDAEFFKKF 

       730        740        750        760        770        780 
RNQNIVLSAR TYAQESNVQA LEILFTYHGS DLLPHRLAIL SNFPETTSPH EYSVLLPEAC 

       790        800        810        820        830        840 
FNGDSLMIIP WHEHKHRAKD WCEELACRMV VEPNLQDESE FLYAAQPELL RFRMTQLTVE 

       850        860        870        880        890        900 
KVMDWYQTRA EEIEHYARQV DCALSLIRLG MERNIPGLLV LCDNLVTLET LVYEARCDVT 

       910        920        930        940        950        960 
LTLKELQQMK DIEKLRLLMN SCSEDKYVTS AYQWMVPFLH RCEKQSPGVA NELLKEYLVT 

       970        980        990       1000       1010       1020 
LAKGDLKFPL KIFQHSKPDL QQKIIPDQDQ LMAIALECIY TCERNDQLCL CYDLLECLPE 

      1030       1040       1050       1060       1070       1080 
RGYGDKTEAT TKLHDMVDQL EQILSVSELL EKHGLEKPIS FVKNTQSSSE EARKLMVRLT 

      1090       1100       1110       1120       1130       1140 
RHTGRKQPPV SESHWRTLLQ DMLTMQQNVY TCLDSDACYE IFTESLLCSS RLENIHLAGQ 

      1150       1160       1170       1180       1190       1200 
MMHCSACSEN PPAGIAHKGK PHYRVSYEKS IDLVLAASRE YFNSSTNLTD SCMDLARCCL 

      1210       1220       1230       1240       1250       1260 
QLITDRPPAI QEELDLIQAV GCLEEFGVKI LPLQVRLCPD RISLIKECIS QSPTCYKQST 

      1270       1280       1290       1300       1310       1320 
KLLGLAELLR VAGENPEERR GQVLILLVEQ ALRFHDYKAA SMHCQELMAT GYPKSWDVCS 

      1330       1340       1350       1360       1370       1380 
QLGQSEGYQD LATRQELMAF ALTHCPPSSI ELLLAASSSL QTEILYQRVN FQIHHEGGEN 

      1390       1400       1410       1420       1430       1440 
ISASPLTSKA VQEDEVGVPG SNSADLLRWT TATTMKVLSN TTTTTKAVLQ AVSDGQWWKK 

      1450       1460       1470       1480       1490       1500 
SLTYLRPLQG QKCGGAYQIG TTANEDLEKQ GCHPFYESVI SNPFVAESEG TYDTYQHVPV 

      1510       1520       1530       1540       1550       1560 
ESFAEVLLRT GKLAEAKNKG EVFPTTEVLL QLASEALPND MTLALAYLLA LPQVLDANRC 

      1570       1580       1590       1600       1610       1620 
FEKQSPSALS LQLAAYYYSL QIYARLAPCF RDKCHPLYRA DPKELIKMVT RHVTRHEHEA 

      1630       1640       1650       1660       1670       1680 
WPEDLISLTK QLHCYNERLL DFTQAQILQG LRKGVDVQRF TADDQYKRET ILGLAETLEE 

      1690       1700       1710       1720       1730       1740 
SVYSIAISLA QRYSVSRWEV FMTHLEFLFT DSGLSTLEIE NRAQDLHLFE TLKTDPEAFH 

      1750       1760       1770       1780       1790       1800 
QHMVKYIYPT IGGFDHERLQ YYFTLLENCG CADLGNCAIK PETHIRLLKK FKVVASGLNY 

      1810       1820       1830       1840       1850       1860 
KKLTDENMSP LEALEPVLSS QNILSISKLV PKIPEKDGQM LSPSSLYTIW LQKLFWTGDP 

      1870       1880       1890       1900       1910       1920 
HLIKQVPGSS PEWLHAYDVC MKYFDRLHPG DLITVVDAVT FSPKAVTKLS VEARKEMTRK 

      1930       1940       1950       1960       1970       1980 
AIKTVKHFIE KPRKRNSEDE AQEAKDSKVT YADTLNHLEK SLAHLETLSH SFILSLKNSE 

      1990       2000       2010       2020       2030       2040 
QETLQKYSHL YDLSRSEKEK LHDEAVAICL DGQPLAMIQQ LLEVAVGPLD ISPKDIVQSA 

      2050       2060       2070       2080       2090       2100 
IMKIISALSG GSADLGGPRD PLKVLEGVVA AVHASVDKGE ELVSPEDLLE WLRPFCADDA 

      2110       2120       2130       2140       2150       2160 
WPVRPRIHVL QILGQSFHLT EEDSKLLVFF RTEAILKASW PQRQVDIADI ENEENRYCLF 

      2170       2180       2190       2200       2210       2220 
MELLESSHHE AEFQHLVLLL QAWPPMKSEY VITNNPWVRL ATVMLTRCTM ENKEGLGNEV 

      2230       2240       2250       2260       2270       2280 
LKMCRSLYNT KQMLPAEGVK ELCLLLLNQS LLLPSLKLLL ESRDEHLHEM ALEQITAVTT 

      2290       2300       2310       2320       2330       2340 
VNDSNCDQEL LSLLLDAKLL VKCVSTPFYP RIVDHLLASL QQGRWDAEEL GRHLREAGHE 

      2350       2360       2370 
AEAGSLLLAV RGTHQAFRTF STALRAAQHW V 

« Hide

Isoform 2 [UniParc].

Checksum: C253AF9620FDA14E
Show »

FASTA2,251254,816

References

« Hide 'large scale' references
[1]"The neuroblastoma amplified gene, NAG: genomic structure and characterisation of the 7.3 kb transcript predominantly expressed in neuroblastoma."
Scott D.K., Board J.R., Lu X., Pearson A.D.J., Kenyon R.M., Lunec J.
Gene 307:1-11(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT ARG-655, TISSUE SPECIFICITY.
Tissue: Neuroblastoma.
[2]"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. expand/collapse author list , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANTS VAL-243 AND ARG-655.
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 834-2371 (ISOFORM 2), VARIANT THR-2074.
Tissue: Eye and PNS.
[4]"Co-amplification of a novel gene, NAG, with the N-myc gene in neuroblastoma."
Wimmer K., Zhu X.X., Lamb B.J., Kuick R., Ambros P.F., Kovar H., Thoraval D., Motyka S., Alberts J.R., Hanash S.M.
Oncogene 18:233-238(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 993-2371 (ISOFORMS 1/2), TISSUE SPECIFICITY.
[5]"The full-ORF clone resource of the German cDNA consortium."
Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1068-2371 (ISOFORMS 1/2).
Tissue: Uterus.
[6]"Gene amplification in PNETs/medulloblastomas: mapping of a novel amplified gene within the MYCN amplicon."
Fruehwald M.C., O'Dorisio M.S., Rush L.J., Reiter J.L., Smiraglia D.J., Wenger G., Costello J.F., White P.S., Krahe R., Brodeur G.M., Plass C.
J. Med. Genet. 37:501-509(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: TISSUE SPECIFICITY.
[7]"A quantitative atlas of mitotic phosphorylation."
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-473 AND SER-475, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[8]"Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
Han G., Ye M., Zhou H., Jiang X., Feng S., Jiang X., Tian R., Wan D., Zou H., Gu J.
Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Liver.
[9]"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[10]"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-473 AND SER-475, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Leukemic T-cell.
[11]"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-1057, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[12]"Neuroblastoma amplified sequence gene is associated with a novel short stature syndrome characterised by optic nerve atrophy and Pelger-Huet anomaly."
Maksimova N., Hara K., Nikolaeva I., Chun-Feng T., Usui T., Takagi M., Nishihira Y., Miyashita A., Fujiwara H., Oyama T., Nogovicina A., Sukhomyasova A., Potapova S., Kuwano R., Takahashi H., Nishizawa M., Onodera O.
J. Med. Genet. 47:538-548(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION, TISSUE SPECIFICITY, VARIANT SOPH HIS-1914, VARIANTS GLU-44; LEU-949 AND SER-1009.
[13]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[14]"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-473 AND SER-475, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF388385 mRNA. Translation: AAM93544.1.
AC007738 Genomic DNA. No translation available.
AC074184 Genomic DNA. No translation available.
AC008278 Genomic DNA. No translation available.
AC008282 Genomic DNA. Translation: AAY24347.1.
BC051792 mRNA. Translation: AAH51792.2.
BC108693 mRNA. Translation: AAI08694.1. Different termination.
BC131735 mRNA. Translation: AAI31736.1.
AF056195 mRNA. Translation: AAD18133.1. Sequence problems.
AL050281 mRNA. Translation: CAB43382.1. Different initiation.
CCDSCCDS1685.1. [A2RRP1-1]
PIRT13150.
RefSeqNP_056993.2. NM_015909.3. [A2RRP1-1]
UniGeneHs.467759.

3D structure databases

ProteinModelPortalA2RRP1.
SMRA2RRP1. Positions 319-349.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid119627. 2 interactions.
DIPDIP-56726N.
IntActA2RRP1. 3 interactions.
MINTMINT-4838513.
STRING9606.ENSP00000281513.

PTM databases

PhosphoSiteA2RRP1.

Proteomic databases

MaxQBA2RRP1.
PaxDbA2RRP1.
PeptideAtlasA2RRP1.
PRIDEA2RRP1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000281513; ENSP00000281513; ENSG00000151779. [A2RRP1-1]
ENST00000441750; ENSP00000413201; ENSG00000151779. [A2RRP1-2]
GeneID51594.
KEGGhsa:51594.
UCSCuc002rcc.2. human. [A2RRP1-1]
uc010exl.1. human. [A2RRP1-2]

Organism-specific databases

CTD51594.
GeneCardsGC02M015224.
H-InvDBHIX0001840.
HGNCHGNC:15625. NBAS.
HPAHPA036817.
MIM608025. gene.
614800. phenotype.
neXtProtNX_A2RRP1.
Orphanet391677. Short stature-optic atrophy-Pelger-Huet anomaly syndrome.
PharmGKBPA164723457.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG293605.
HOGENOMHOG000113737.
InParanoidA2RRP1.
OMAIDVNWWA.
OrthoDBEOG7C5M7C.
PhylomeDBA2RRP1.
TreeFamTF313901.

Gene expression databases

ArrayExpressA2RRP1.
BgeeA2RRP1.
GenevestigatorA2RRP1.

Family and domain databases

Gene3D2.130.10.10. 3 hits.
InterProIPR029145. NBAS_N.
IPR011044. Quino_amine_DH_bsu.
IPR013244. Sec39.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamPF15492. Nbas_N. 1 hit.
PF08314. Sec39. 1 hit.
[Graphical view]
SUPFAMSSF50969. SSF50969. 2 hits.
ProtoNetSearch...

Other

ChiTaRSNBAS. human.
GenomeRNAi51594.
NextBio55444.
PROA2RRP1.
SOURCESearch...

Entry information

Entry nameNBAS_HUMAN
AccessionPrimary (citable) accession number: A2RRP1
Secondary accession number(s): O95790 expand/collapse secondary AC list , Q2VPJ7, Q53TK6, Q86V39, Q8NFY8, Q9Y3W5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: March 3, 2009
Last modified: July 9, 2014
This is version 67 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 2

Human chromosome 2: entries, gene names and cross-references to MIM