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Protein
Submitted name:

Bcr protein

Gene

Bcr

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGTPase activationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Bcr proteinImported
Gene namesi
Name:BcrImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88141 Bcr

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiA2RRK7
PeptideAtlasiA2RRK7
PRIDEiA2RRK7

Expressioni

Gene expression databases

GenevisibleiA2RRK7 MM

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA2RRK7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini210 – 403DHInterPro annotationAdd BLAST194
Domaini420 – 578PHInterPro annotationAdd BLAST159
Domaini582 – 714C2InterPro annotationAdd BLAST133
Domaini766 – 960Rho-GAPInterPro annotationAdd BLAST195

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili496 – 516Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4269 Eukaryota
ENOG410XPGZ LUCA
HOVERGENiHBG004165
KOiK08878

Family and domain databases

CDDicd00160 RhoGEF, 1 hit
Gene3Di1.10.555.10, 1 hit
1.20.900.10, 1 hit
2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR037769 Abr/Bcr
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR001331 GDS_CDC24_CS
IPR001849 PH_domain
IPR008936 Rho_GTPase_activation_prot
IPR000198 RhoGAP_dom
PANTHERiPTHR23182 PTHR23182, 1 hit
PfamiView protein in Pfam
PF00168 C2, 1 hit
PF00620 RhoGAP, 1 hit
PF00621 RhoGEF, 1 hit
SMARTiView protein in SMART
SM00239 C2, 1 hit
SM00233 PH, 1 hit
SM00324 RhoGAP, 1 hit
SM00325 RhoGEF, 1 hit
SUPFAMiSSF48065 SSF48065, 1 hit
SSF48350 SSF48350, 1 hit
PROSITEiView protein in PROSITE
PS50004 C2, 1 hit
PS00741 DH_1, 1 hit
PS50010 DH_2, 1 hit
PS50003 PH_DOMAIN, 1 hit
PS50238 RHOGAP, 1 hit

Sequencei

Sequence statusi: Complete.

A2RRK7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMVEGEGKSP LLRSQSTSEQ EKRLTWPRRS YSPRSFEDSG GGYTPDCSSN
60 70 80 90 100
ENLTSSEEDF SSGQSSRVSP SPTTYRMFRD KSRSPSQNSQ QSFDSSSPPT
110 120 130 140 150
PQCQKRHRQC QVVVSEATIV GVRKTGQIWP SDGDSTFQGE ADSSFGTPPG
160 170 180 190 200
YGCAADQAEE QRRHQDGLPY IDDSPSSSPH LSSKGRGSLA SGALDPTKVS
210 220 230 240 250
ELDLEKGLEM RKWVLSGILA SEETYLSHLE ALLLPMKPLK AAATTSQPVL
260 270 280 290 300
TSQQIETIFF KVPELYEIHK EFYDGLFPRV QQWSHQQRVG DLFQKLASQL
310 320 330 340 350
GVYRAFVDNY GVAMETAEKC CQANAQFAEI SENLRARSNK DVKDSTTKNS
360 370 380 390 400
LETLLYKPVD RVTRSTLVLH DLLKHTPSSH PDHSLLQDAL RISQNFLSSI
410 420 430 440 450
NEEITPRRQS MTVKKGEHRQ LLKDSFMVEL VEGARKLRHI FLFTDLLLCT
460 470 480 490 500
KLKKQSGGKT QQYDCKWYIP LTDLSFQMVD ELEALPNIPL VPDEELDALK
510 520 530 540 550
IKISQIKSDI QREKRANKGS KVMERLRKKL SEQESLLLLM SPSMAFRVHS
560 570 580 590 600
RNGKSYTFLI SSDYERAEWR ESIREQQKKC FKSFSLTSVE LQMLTNSCVK
610 620 630 640 650
LQTVHHIPLT INKEDDESPG LYGFLHVIVH SATGFKQSSN LYCTLEVDSF
660 670 680 690 700
GYFVNKAKTR VYRDTTEPNW NEEFEIELEG SQTLRILCYE KCYNKMKMTK
710 720 730 740 750
EDGESADKLM GKGQVQLDPQ TLQDRDWQRT VIDMNGIEVK LSVKFTSREF
760 770 780 790 800
SLKRMPSRKQ TGVFGVKIAV VTKRERSKVP YIVRQCVEEI ERRGMEEVGI
810 820 830 840 850
YRVSGVATDI QALKAAFDVN NKDVSVMMSE MDVNAIAGTL KLYFRELPEP
860 870 880 890 900
LFTDEFYPNF AEGIALSDPV AKESCMLNLL LSLPEANLLT FLFLLDHLKR
910 920 930 940 950
VAEKETVNKM SLHNLATVFG PTLLRPSEKE SKLPANPSQP ITMTDSWSLE
960 970 980
VMSQVQVLLY FLQLEAIPAP DSKRQSILFS TEV
Length:983
Mass (Da):111,408
Last modified:March 6, 2007 - v1
Checksum:i646342E79412DECE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC131682 mRNA Translation: AAI31683.1
RefSeqiNP_001074881.1, NM_001081412.2
UniGeneiMm.333722

Genome annotation databases

GeneIDi110279
KEGGimmu:110279

Similar proteinsi

Entry informationi

Entry nameiA2RRK7_MOUSE
AccessioniPrimary (citable) accession number: A2RRK7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: March 28, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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