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Protein
Submitted name:

WD repeat-containing protein 7

Gene

WDR7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
WD repeat-containing protein 7Imported
Submitted name:
WDR7 proteinImported
Gene namesi
Name:WDR7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000091157.13.
HGNCiHGNC:13490. WDR7.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000091157.

Expressioni

Gene expression databases

BgeeiENSG00000091157.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
FRMD6Q96NE93EBI-10291832,EBI-741729

Protein-protein interaction databases

IntActiA2RRE0. 1 interactor.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 56WD_REPEATS_REGIONInterPro annotationAdd BLAST42
Repeati22 – 49WDPROSITE-ProRule annotationAdd BLAST28
Domaini715 – 757WD_REPEATS_REGIONInterPro annotationAdd BLAST43
Repeati715 – 751WDPROSITE-ProRule annotationAdd BLAST37

Keywords - Domaini

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410ISJ1. Eukaryota.
ENOG410Y2AE. LUCA.
GeneTreeiENSGT00520000055590.
HOGENOMiHOG000236256.
HOVERGENiHBG080660.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
2.130.10.10. 2 hits.
InterProiView protein in InterPro
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
IPR036322. WD40_repeat_dom_sf.
PfamiView protein in Pfam
PF00400. WD40. 2 hits.
SMARTiView protein in SMART
SM00320. WD40. 2 hits.
SUPFAMiSSF48371. SSF48371. 2 hits.
SSF50978. SSF50978. 2 hits.
PROSITEiView protein in PROSITE
PS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 2 hits.

Sequencei

Sequence statusi: Complete.

A2RRE0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGNSLVLPI VLWGRKAPTH CISAVLLTDD GATIVTGCHD GQICLWDLSV
60 70 80 90 100
ELQINPRALL FGHTAVLFQQ VKETIKENIK EHLLDDEEED EEIMRQRREE
110 120 130 140 150
SDPEYRSSKS KPLTLLEYNL TMDTAKLFMS CLHAWGLNEV LDEVCLDRLG
160 170 180 190 200
MLKPHCTVSF GLLSRGGHMS LMLPGYNQPA CKLSHGKTEV GRKLPASEGV
210 220 230 240 250
GKGTYGVSRA VTTQHLLSII SLANTLMSMT NATFIGDHMK KGPTRPPRPS
260 270 280 290 300
TPDLSKARGS PPTSSNIVQG QIKQVAAPVV SARSDADHSG SDPPSAPALH
310 320 330 340 350
TCFLVNEGWS QLAAMHCVML PDLLGLDKFR PPLLEMLARR WQDRCLEVRE
360 370 380 390 400
AAQALLLAEL RRIEQAGRKE AIDAWAPYLP QYIDHVISPG VTSEAAQTIT
410 420 430 440 450
TAPDASGPEA KVQEEEHDLV DDDITTGCLS SVPQMKKIST SYEERRKQAT
460 470 480 490 500
AIVLLGVIGA EFGAEIEPPK LLTRPRSSSQ IPEGFGLTSG GSNYSLARHT
510 520 530 540 550
CKALTFLLLQ PPSPKLPPHS TIRRTAIDLI GRGFTVWEPY MDVSAVLMGL
560 570 580 590 600
LELCADAEKQ LANITMGLPL SPAADSARSA RHALSLIATA RPPAFITTIA
610 620 630 640 650
KEVHRHTALA ANTQSQQNMH TTTLARAKGE ILRVIEILIE KMPTDVVDLL
660 670 680 690 700
VEVMDIIMYC LEGSLVKKKG LQECFPAICR FYMVSYYERN HRIAVGARHG
710 720 730 740 750
SVALYDIRTG KCQTIHGHKG PITAVAFAPD GRYLATYSNT DSHISFWQMN
760 770 780 790 800
TSLLGSIGML NSAPQLRCIK TYQVPPVQPA SPGSHNALKL ARLIWTSNRN
810
VILMAHDGKE HRFMV
Length:815
Mass (Da):89,344
Last modified:March 6, 2007 - v1
Checksum:iB33944DE3174B27A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007052 Genomic DNA. No translation available.
AC008006 Genomic DNA. No translation available.
AC012301 Genomic DNA. No translation available.
BC131558 mRNA. Translation: AAI31559.1.
UniGeneiHs.465213.

Genome annotation databases

EnsembliENST00000615645; ENSP00000481823; ENSG00000091157.
UCSCiuc060plr.1. human.

Similar proteinsi

Entry informationi

Entry nameiA2RRE0_HUMAN
AccessioniPrimary (citable) accession number: A2RRE0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: October 25, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported