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Protein
Submitted name:

WD repeat-containing protein 7

Gene

WDR7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
WD repeat-containing protein 7Imported
Submitted name:
WDR7 proteinImported
Gene namesi
Name:WDR7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

HGNCiHGNC:13490. WDR7.

PTM / Processingi

Proteomic databases

PeptideAtlasiA2RRE0.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
FRMD6Q96NE93EBI-10291832,EBI-741729

Protein-protein interaction databases

STRINGi9606.ENSP00000254442.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini15 – 5642WD_REPEATS_REGIONInterPro annotationAdd
BLAST
Domaini715 – 75743WD_REPEATS_REGIONInterPro annotationAdd
BLAST

Keywords - Domaini

RepeatUniRule annotation

Phylogenomic databases

eggNOGiENOG410ISJ1. Eukaryota.
ENOG410Y2AE. LUCA.
GeneTreeiENSGT00520000055590.
HOGENOMiHOG000236256.
HOVERGENiHBG080660.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR016024. ARM-type_fold.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 2 hits.
[Graphical view]
SMARTiSM00320. WD40. 2 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 2 hits.
SSF50978. SSF50978. 2 hits.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2RRE0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGNSLVLPI VLWGRKAPTH CISAVLLTDD GATIVTGCHD GQICLWDLSV
60 70 80 90 100
ELQINPRALL FGHTAVLFQQ VKETIKENIK EHLLDDEEED EEIMRQRREE
110 120 130 140 150
SDPEYRSSKS KPLTLLEYNL TMDTAKLFMS CLHAWGLNEV LDEVCLDRLG
160 170 180 190 200
MLKPHCTVSF GLLSRGGHMS LMLPGYNQPA CKLSHGKTEV GRKLPASEGV
210 220 230 240 250
GKGTYGVSRA VTTQHLLSII SLANTLMSMT NATFIGDHMK KGPTRPPRPS
260 270 280 290 300
TPDLSKARGS PPTSSNIVQG QIKQVAAPVV SARSDADHSG SDPPSAPALH
310 320 330 340 350
TCFLVNEGWS QLAAMHCVML PDLLGLDKFR PPLLEMLARR WQDRCLEVRE
360 370 380 390 400
AAQALLLAEL RRIEQAGRKE AIDAWAPYLP QYIDHVISPG VTSEAAQTIT
410 420 430 440 450
TAPDASGPEA KVQEEEHDLV DDDITTGCLS SVPQMKKIST SYEERRKQAT
460 470 480 490 500
AIVLLGVIGA EFGAEIEPPK LLTRPRSSSQ IPEGFGLTSG GSNYSLARHT
510 520 530 540 550
CKALTFLLLQ PPSPKLPPHS TIRRTAIDLI GRGFTVWEPY MDVSAVLMGL
560 570 580 590 600
LELCADAEKQ LANITMGLPL SPAADSARSA RHALSLIATA RPPAFITTIA
610 620 630 640 650
KEVHRHTALA ANTQSQQNMH TTTLARAKGE ILRVIEILIE KMPTDVVDLL
660 670 680 690 700
VEVMDIIMYC LEGSLVKKKG LQECFPAICR FYMVSYYERN HRIAVGARHG
710 720 730 740 750
SVALYDIRTG KCQTIHGHKG PITAVAFAPD GRYLATYSNT DSHISFWQMN
760 770 780 790 800
TSLLGSIGML NSAPQLRCIK TYQVPPVQPA SPGSHNALKL ARLIWTSNRN
810
VILMAHDGKE HRFMV
Length:815
Mass (Da):89,344
Last modified:March 6, 2007 - v1
Checksum:iB33944DE3174B27A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007052 Genomic DNA. No translation available.
AC008006 Genomic DNA. No translation available.
AC012301 Genomic DNA. No translation available.
BC131558 mRNA. Translation: AAI31559.1.
UniGeneiHs.465213.

Genome annotation databases

EnsembliENST00000615645; ENSP00000481823; ENSG00000091157.
UCSCiuc060plr.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007052 Genomic DNA. No translation available.
AC008006 Genomic DNA. No translation available.
AC012301 Genomic DNA. No translation available.
BC131558 mRNA. Translation: AAI31559.1.
UniGeneiHs.465213.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000254442.

Proteomic databases

PeptideAtlasiA2RRE0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000615645; ENSP00000481823; ENSG00000091157.
UCSCiuc060plr.1. human.

Organism-specific databases

HGNCiHGNC:13490. WDR7.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410ISJ1. Eukaryota.
ENOG410Y2AE. LUCA.
GeneTreeiENSGT00520000055590.
HOGENOMiHOG000236256.
HOVERGENiHBG080660.

Miscellaneous databases

ChiTaRSiWDR7. human.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR016024. ARM-type_fold.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 2 hits.
[Graphical view]
SMARTiSM00320. WD40. 2 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 2 hits.
SSF50978. SSF50978. 2 hits.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. Ensembl
    Submitted (SEP-2014) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiA2RRE0_HUMAN
AccessioniPrimary (citable) accession number: A2RRE0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: July 6, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.