A2RLP2 (A2RLP2_LACLM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Malolactic enzyme EMBL CAL98212.1
EC=1.1.1.38 EMBL CAL98212.1

Gene names

Name:	mleS EMBL CAL98212.1
Ordered Locus Names:	llmg_1638

Organism

Lactococcus lactis subsp. cremoris (strain MG1363) [Complete proteome] [HAMAP]

Taxonomic identifier

416870 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length	540 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the malic enzymes family. RuleBase RU003427

Ontologies

Keywords
Ligand	Metal-binding RuleBase RU003427
Molecular function	Oxidoreductase RuleBase RU003427 EMBL CAL98212.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	malate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	NAD binding Inferred from electronic annotation. Source: InterPro malate dehydrogenase (oxaloacetate-decarboxylating) activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2RLP2 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: 8110193576D5F293	FASTA	540	59,500
	10 20 30 40 50 60 MRAHEILNNP FLNKGTAFTM KERQELGLIG LLPPTVQTIE EQAEQTYEQY LTKPSDLEKR 70 80 90 100 110 120 HFLMEIFNTN RTLFYYLFNK HIVEFNPVVY DPTIADTIEN YSHLFVDPQY AAYLDINHPE 130 140 150 160 170 180 NITETLKNAA GDRDIRLIVV TDAEGILGIG DWGTQGVDIS VGKLMIYTAA AGIDPASVLP 190 200 210 220 230 240 VVIDAGTNRK ELLEDHLYLG NHQERIYGDQ YYSFVDQFVE TAESIFPKLY LHWEDFGRSN 250 260 270 280 290 300 AATILNNYKT KIPTFNDDIQ GTGIVVLGGI FGSLDITGEK LTDQVYLCYG GGSAGAGIAG 310 320 330 340 350 360 RVHAEMVSEG LSEEEAYKHF FMIDQQGLLF DDMDDLTPAQ KPFAKKRADY KDAGDMTDLL 370 380 390 400 410 420 NIVKTVKPTI LVGTSTNPGA FTKEVVEAMC ANTERPVIFP ISNPTKKMEA TAEQVIEWSD 430 440 450 460 470 480 GKAFVATGVP SGTINYKGVD YQIGQANNSL IYPGLGLGML ASEAKLLTDE MIGAAAHSLS 490 500 510 520 530 540 GLVDPGKPGA PVLPPFEFVA DVSIKVAEAV AKKAQEQGLT ESKETDMAKA VRDLKWYPEY

References

[1]

"The complete genome sequence of the lactic acid bacterial paradigm Lactococcus lactis subsp. cremoris MG1363." Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C., Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P., van Sinderen D., Kok J. J. Bacteriol. 189:3256-3270(2007) [PubMed: 17307855] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM406671 Genomic DNA. Translation: CAL98212.1.
RefSeq	YP_001032920.1. NC_009004.1.
3D structure databases
ProteinModelPortal	A2RLP2.
ModBase	Search...
Protein-protein interaction databases
STRING	A2RLP2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4798616.
GenomeReviews	Gene locus llmg_1638 in contig AM406671_GR.
KEGG	llm:llmg_1638.
PATRIC	22284450. VBILacLac4574_1680.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0281.
HOGENOM	HBG289821.
OMA	QDNNETL.
ProtClustDB	PRK13529.
Family and domain databases
InterPro	IPR015884. Malic_enzyme_CS. IPR012301. Malic_N. IPR012302. Malic_NAD-bd. IPR001891. Malic_OxRdtase. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.10380. G3DSA:3.40.50.10380. 1 hit. G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00027.
Pfam	PF00390. malic. 1 hit. PF03949. Malic_M. 1 hit. [Graphical view]
PIRSF	PIRSF000106. ME. 1 hit.
PRINTS	PR00072. MALOXRDTASE.
SMART	SM00919. Malic_M. 1 hit. [Graphical view]
PROSITE	PS00331. MALIC_ENZYMES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A2RLP2_LACLM

Accession

Primary (citable) accession number: A2RLP2

Entry history

Integrated into UniProtKB/TrEMBL:	March 6, 2007
Last sequence update:	March 6, 2007
Last modified:	December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)