A2RLJ5 (A2RLJ5_LACLM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Thioredoxin reductase RuleBase RU003881
EC=1.8.1.9 RuleBase RU003881

Gene names

Name:	trxB1 EMBL CAL98163.1
Ordered Locus Names:	llmg_1588

Organism

Lactococcus lactis subsp. cremoris (strain MG1363) [Complete proteome] [HAMAP]

Taxonomic identifier

416870 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length	308 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Thioredoxin + NADP+ = thioredoxin disulfide + NADPH. RuleBase RU003881
Cofactor	Binds 1 FAD per subunit By similarity. RuleBase RU003881
Sequence similarities	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. RuleBase RU003880

Ontologies

Keywords
Domain	Redox-active center RuleBase RU003880
Ligand	FAD RuleBase RU003880 Flavoprotein RuleBase RU003880
Molecular function	Oxidoreductase RuleBase RU003880 EMBL CAL98163.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	removal of superoxide radicals Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro thioredoxin-disulfide reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2RLJ5 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: B7F5BF85E66B8C44	FASTA	308	33,951
	10 20 30 40 50 60 MTEKKYDVVI IGSGPAGMTA AMYTARSEMK TLLLERGVPG GQMNNTAEIE NYPGYETIMG 70 80 90 100 110 120 PELSMKMAEP LEGLGVENAY GFVTGIEDHG DYKKIITEDD EFITKSIIIA TGANHRKLEI 130 140 150 160 170 180 PGEEEYGARG VSYCAVCDGA FFRNQEILVI GGGDSAVEEA LYLTRFGQSV TIMHRRDKLR 190 200 210 220 230 240 AQEIIQQRAF KEEKINFIWD SVPMEIKGDD KKIQSVVYKN VKTGEVTEKA FGGIFIYVGL 250 260 270 280 290 300 DPVAEFVSDL GITDEAGWII TDDHMRTNIP GIFAVGDVRQ KDFRQITTAV GDGAQAAQEA YKFVVELG

References

[1]

"The complete genome sequence of the lactic acid bacterial paradigm Lactococcus lactis subsp. cremoris MG1363." Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C., Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P., van Sinderen D., Kok J. J. Bacteriol. 189:3256-3270(2007) [PubMed: 17307855] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM406671 Genomic DNA. Translation: CAL98163.1.
RefSeq	YP_001032873.1. NC_009004.1.
3D structure databases
ProteinModelPortal	A2RLJ5.
ModBase	Search...
Protein-protein interaction databases
STRING	A2RLJ5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4798271.
GenomeReviews	Gene locus llmg_1588 in contig AM406671_GR.
KEGG	llm:llmg_1588.
PATRIC	22284346. VBILacLac4574_1628.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0492.
HOGENOM	HBG669726.
OMA	AVEEAMY.
ProtClustDB	CLSK2458888.
Family and domain databases
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR008255. Pyr_nucl-diS_OxRdtase_2_AS. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR000103. Pyridine_nuc-diS_OxRdtase_2. IPR005982. Thioredox_Rdtase. [Graphical view]
KO	K00384.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
TIGRFAMs	TIGR01292. TRX_reduct. 1 hit.
PROSITE	PS00573. PYRIDINE_REDOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A2RLJ5_LACLM

Accession

Primary (citable) accession number: A2RLJ5

Entry history

Integrated into UniProtKB/TrEMBL:	March 6, 2007
Last sequence update:	March 6, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)