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A2RIZ1

- A2RIZ1_LACLM

UniProt

A2RIZ1 - A2RIZ1_LACLM

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Protein

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
Lactococcus lactis subsp. cremoris (strain MG1363)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Enzyme and pathway databases

BioCyciLLAC416870:GCDT-668-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Name:icdImported
Ordered Locus Names:llmg_0637Imported
OrganismiLactococcus lactis subsp. cremoris (strain MG1363)Imported
Taxonomic identifieri416870 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
ProteomesiUP000000364: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi416870.llmg_0637.

Structurei

3D structure databases

ProteinModelPortaliA2RIZ1.
SMRiA2RIZ1. Positions 2-409.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0538.
HOGENOMiHOG000021113.
KOiK00031.
OMAiCLRPIRY.
OrthoDBiEOG6SNDTP.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2RIZ1-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MKIEMKNGKL IVPDYPTIGY IRGDGVGEDI FPQAKRVFDA AVLKIFGEKK
60 70 80 90 100
KIDWQKLLAG GEAFASRGEY LPDETLEQIK ENLIAIKGPL MTPVGESFRS
110 120 130 140 150
INVTLRQKLD LYACVRPVEY FTGIKSPVRA PEKVNMTIFR ENTEDIYAGI
160 170 180 190 200
EFSSSSKESK KLINFLEREL SVHSIRFPET SAIGIKPVSP DGSKRLVSAA
210 220 230 240 250
FDYAIKMNKK RVTFVHKGNI MKFTEGGFRK WGYEVAKNYP TFTKLEYDKI
260 270 280 290 300
KEEKGTEQSE KEKNIALKSG KIYVDDAIAD NFLQQIILNP DNFEVVATLN
310 320 330 340 350
LNGDYISDAL AAQVGGIGIA PGANINYESG HAIFEATHGT APDIAGKNIA
360 370 380 390 400
NPSSLILSGV MMFEYLGWQE VAELIKIALS ASFHSGALTA DLGGKLSTSE
410
FTDTLVQYIK NY
Length:412
Mass (Da):45,612
Last modified:March 6, 2007 - v1
Checksum:i0BFC270CD67AFFAD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM406671 Genomic DNA. Translation: CAL97239.1.
RefSeqiYP_001031980.1. NC_009004.1.

Genome annotation databases

EnsemblBacteriaiCAL97239; CAL97239; llmg_0637.
GeneIDi4796910.
KEGGillm:llmg_0637.
PATRICi22282374. VBILacLac4574_0652.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM406671 Genomic DNA. Translation: CAL97239.1 .
RefSeqi YP_001031980.1. NC_009004.1.

3D structure databases

ProteinModelPortali A2RIZ1.
SMRi A2RIZ1. Positions 2-409.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 416870.llmg_0637.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAL97239 ; CAL97239 ; llmg_0637 .
GeneIDi 4796910.
KEGGi llm:llmg_0637.
PATRICi 22282374. VBILacLac4574_0652.

Phylogenomic databases

eggNOGi COG0538.
HOGENOMi HOG000021113.
KOi K00031.
OMAi CLRPIRY.
OrthoDBi EOG6SNDTP.

Enzyme and pathway databases

BioCyci LLAC416870:GCDT-668-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of the lactic acid bacterial paradigm Lactococcus lactis subsp. cremoris MG1363."
    Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C., Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P., van Sinderen D., Kok J.
    J. Bacteriol. 189:3256-3270(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MG1363Imported.

Entry informationi

Entry nameiA2RIZ1_LACLM
AccessioniPrimary (citable) accession number: A2RIZ1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: October 1, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3