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Protein
Submitted name:

Isocitrate dehydrogenase

Gene

icd

Organism
Lactococcus lactis subsp. cremoris (strain MG1363)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenaseImported (EC:1.1.1.42Imported)
Gene namesi
Name:icdImported
Ordered Locus Names:llmg_0637Imported
OrganismiLactococcus lactis subsp. cremoris (strain MG1363)Imported
Taxonomic identifieri416870 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
Proteomesi
  • UP000000364 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi416870.llmg_0637.

Structurei

3D structure databases

ProteinModelPortaliA2RIZ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 405Iso_dhInterPro annotationAdd BLAST389

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108HMX. Bacteria.
COG0538. LUCA.
HOGENOMiHOG000021113.
KOiK00031.
OMAiTERESWI.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 3 hits.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
SMARTiSM01329. Iso_dh. 1 hit.
[Graphical view]
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2RIZ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIEMKNGKL IVPDYPTIGY IRGDGVGEDI FPQAKRVFDA AVLKIFGEKK
60 70 80 90 100
KIDWQKLLAG GEAFASRGEY LPDETLEQIK ENLIAIKGPL MTPVGESFRS
110 120 130 140 150
INVTLRQKLD LYACVRPVEY FTGIKSPVRA PEKVNMTIFR ENTEDIYAGI
160 170 180 190 200
EFSSSSKESK KLINFLEREL SVHSIRFPET SAIGIKPVSP DGSKRLVSAA
210 220 230 240 250
FDYAIKMNKK RVTFVHKGNI MKFTEGGFRK WGYEVAKNYP TFTKLEYDKI
260 270 280 290 300
KEEKGTEQSE KEKNIALKSG KIYVDDAIAD NFLQQIILNP DNFEVVATLN
310 320 330 340 350
LNGDYISDAL AAQVGGIGIA PGANINYESG HAIFEATHGT APDIAGKNIA
360 370 380 390 400
NPSSLILSGV MMFEYLGWQE VAELIKIALS ASFHSGALTA DLGGKLSTSE
410
FTDTLVQYIK NY
Length:412
Mass (Da):45,612
Last modified:March 6, 2007 - v1
Checksum:i0BFC270CD67AFFAD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM406671 Genomic DNA. Translation: CAL97239.1.
RefSeqiWP_011834646.1. NC_009004.1.

Genome annotation databases

EnsemblBacteriaiCAL97239; CAL97239; llmg_0637.
KEGGillm:llmg_0637.
PATRICi22282374. VBILacLac4574_0652.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM406671 Genomic DNA. Translation: CAL97239.1.
RefSeqiWP_011834646.1. NC_009004.1.

3D structure databases

ProteinModelPortaliA2RIZ1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi416870.llmg_0637.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL97239; CAL97239; llmg_0637.
KEGGillm:llmg_0637.
PATRICi22282374. VBILacLac4574_0652.

Phylogenomic databases

eggNOGiENOG4108HMX. Bacteria.
COG0538. LUCA.
HOGENOMiHOG000021113.
KOiK00031.
OMAiTERESWI.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 3 hits.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
SMARTiSM01329. Iso_dh. 1 hit.
[Graphical view]
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA2RIZ1_LACLM
AccessioniPrimary (citable) accession number: A2RIZ1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: November 2, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.