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A2RIR2 (A2RIR2_LACLM) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length189 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124 RuleBase RU000544 SAAS SAAS020634

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124 SAAS SAAS020633

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124 SAAS SAAS020633.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding85 – 884ATP By similarity HAMAP-Rule MF_00124

Sites

Active site861Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1431Zinc By similarity HAMAP-Rule MF_00124
Metal binding1461Zinc By similarity HAMAP-Rule MF_00124
Metal binding1801Zinc By similarity HAMAP-Rule MF_00124
Metal binding1831Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
A2RIR2 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: 3C5BC04236E4B8DE

FASTA18921,412
        10         20         30         40         50         60 
MAQLYFKYGT MNSGKSIEIL KVAHNYEEQG KPVLLMTSSL DTRAGVGTVA SRIGMKAEAI 

        70         80         90        100        110        120 
AIDDKMSVFD YVNSLSAKPF CVLIDEAQFL NKKHVYDFAR VVDELNVPVM AFGLKNDFRN 

       130        140        150        160        170        180 
ELFEGSKYLL LLADKIEEIK TICWYCSKKA TMVIRTIDGK PVYEGEQLQI GGNETYIPVC 


RKHYFKPEI 

« Hide

References

[1]"The complete genome sequence of the lactic acid bacterial paradigm Lactococcus lactis subsp. cremoris MG1363."
Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C., Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P., van Sinderen D., Kok J.
J. Bacteriol. 189:3256-3270(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MG1363 EMBL CAL97157.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM406671 Genomic DNA. Translation: CAL97157.1.
RefSeqYP_001031903.1. NC_009004.1.

3D structure databases

ProteinModelPortalA2RIR2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING416870.llmg_0555.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAL97157; CAL97157; llmg_0555.
GeneID4797965.
KEGGllm:llmg_0555.
PATRIC22282195. VBILacLac4574_0565.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1435.
HOGENOMHOG000076391.
KOK00857.
OMARTICHCG.
OrthoDBEOG69D3J2.
ProtClustDBPRK04296.

Enzyme and pathway databases

BioCycLLAC416870:GCDT-584-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA2RIR2_LACLM
AccessionPrimary (citable) accession number: A2RIR2
Entry history
Integrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: April 16, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)