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A2RHJ6 (A2RHJ6_LACLM) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phospho-2-dehydro-3-deoxyheptonate aldolase PIRNR PIRNR001361
EC=2.5.1.54 PIRNR PIRNR001361
Alternative name(s):
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase PIRNR PIRNR001361
DAHP synthase PIRNR PIRNR001361
Phospho-2-keto-3-deoxyheptonate aldolase PIRNR PIRNR001361
Gene names
Name:aroF EMBL CAL96732.1
Ordered Locus Names:llmg_0125
OrganismLactococcus lactis subsp. cremoris (strain MG1363) [Complete proteome] [HAMAP]
Taxonomic identifier416870 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length345 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) By similarity. PIRNR PIRNR001361

Catalytic activity

Phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate. PIRNR PIRNR001361

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7. PIRNR PIRNR001361

Sequence similarities

Belongs to the class-I DAHP synthase family. PIRNR PIRNR001361

Sequences

Sequence LengthMass (Da)Tools
A2RHJ6 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: 0B047853380D4613

FASTA34539,253
        10         20         30         40         50         60 
MTFKEISPKI NIDAIKMLGH LNSEQQEKKM LRDKELEAII KGEDDRLLLI IGPCSSDNEE 

        70         80         90        100        110        120 
AVLEYARRLA KLQEAVKDKI FMVMRVYTAK PRTNGDGYKG LIHEPDADGH TDLINGIKMV 

       130        140        150        160        170        180 
RDLHYKVITE TGLTTADEML YPENLPMVDD LVSYHAIGAR SVENQQHRFV ASGIDVPTGL 

       190        200        210        220        230        240 
KNPTSGNLKV MFNGIYAAQQ SQDFLFGRAE VQTSGNPLAH AILRGGQDEN GKYHPNYYTD 

       250        260        270        280        290        300 
NLLETIEIYE KMGLKNPFIL IDTNHDNSGK KFMEQIRIVR QTLVNRDWDD KIRQNVRGFM 

       310        320        330        340 
IESYLEDGRQ DKPEVFGKSI TDPCLGWDKT EALVQEIYEA ESKNK

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References

[1]"The complete genome sequence of the lactic acid bacterial paradigm Lactococcus lactis subsp. cremoris MG1363."
Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C., Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P., van Sinderen D., Kok J.
J. Bacteriol. 189:3256-3270(2007) [PubMed: 17307855] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM406671 Genomic DNA. Translation: CAL96732.1.
RefSeqYP_001031487.1. NC_009004.1.

3D structure databases

ProteinModelPortalA2RHJ6.
ModBaseSearch...

Protein-protein interaction databases

STRINGA2RHJ6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4797238.
GenomeReviewsGene locus llmg_0125 in contig AM406671_GR.
KEGGllm:llmg_0125.
PATRIC22281250. VBILacLac4574_0122.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0722.
HOGENOMHBG670536.
OMAMDNSFKL.
ProtClustDBPRK09261.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006219. DHAP_synth_1.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01626.
PANTHERPTHR21225. AroFGH. 1 hit.
PfamPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
PIRSFPIRSF001361. DAHP_synthase. 1 hit.
TIGRFAMsTIGR00034. AroFGH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA2RHJ6_LACLM
AccessionPrimary (citable) accession number: A2RHJ6
Entry history
Integrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info