A2RF19 (A2RF19_STRPG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrofolate reductase EMBL CAM30445.1
EC=1.5.1.3 EMBL CAM30445.1

Gene names

Name:	dyr EMBL CAM30445.1
Ordered Locus Names:	SpyM51119

Organism

Streptococcus pyogenes serotype M5 (strain Manfredo) [Complete proteome] [HAMAP]

Taxonomic identifier

160491 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	165 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL CAM30445.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2RF19 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: 4AB6C2B9E4851805	FASTA	165	19,362
	10 20 30 40 50 60 MTKEIIAIWA EDEAGLIGVA GKLPWYLPKE LEHFKKTTLH QAILMGRVTF EGMNCKRLSQ 70 80 90 100 110 120 RQTLVMTRNR DYQVDEVLTM TSIEKVLEWY HAQDKTLYII GGNKVLEAFN GYFDRIIKTV 130 140 150 160 IHHRFKGDTY RPNLDFSHFT QESQTFYARD AKNPYDFTVT ALKHK

References

[1]

"Complete genome of acute rheumatic fever-associated serotype M5 Streptococcus pyogenes strain Manfredo." Holden M.T.G., Scott A., Cherevach I., Chillingworth T., Churcher C., Cronin A., Dowd L., Feltwell T., Hamlin N., Holroyd S., Jagels K., Moule S., Mungall K., Quail M.A., Price C., Rabbinowitsch E., Sharp S., Skelton J. , Whitehead S., Barrell B.G., Kehoe M., Parkhill J. J. Bacteriol. 189:1473-1477(2007) [PubMed: 17012393] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM295007 Genomic DNA. Translation: CAM30445.1.
RefSeq	YP_001128668.1. NC_009332.1.
3D structure databases
ProteinModelPortal	A2RF19.
ModBase	Search...
Protein-protein interaction databases
STRING	A2RF19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000048775; EBSTRP00000046903; EBSTRG00000048767.
GeneID	4963497.
GenomeReviews	Gene locus SpyM51119 in contig AM295007_GR.
KEGG	spf:SpyM51119.
PATRIC	19765420. VBIStrPyo41547_1162.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0262.
GeneTree	EBGT00050000027355.
HOGENOM	HBG665708.
OMA	YITHILQ.
ProtClustDB	CLSK797453.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
KO	K00287.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A2RF19_STRPG

Accession

Primary (citable) accession number: A2RF19

Entry history

Integrated into UniProtKB/TrEMBL:	March 6, 2007
Last sequence update:	March 6, 2007
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)