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A2RF09 (DEOD_STRPG) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Purine nucleoside phosphorylase DeoD-type

Short name=PNP
EC=2.4.2.1
Gene names
Name:deoD
Ordered Locus Names:SpyM51109
OrganismStreptococcus pyogenes serotype M5 (strain Manfredo) [Complete proteome] [HAMAP]
Taxonomic identifier160491 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length237 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Subunit structure

Homohexamer By similarity. HAMAP-Rule MF_01627

Sequence similarities

Belongs to the PNP/UDP phosphorylase family.

Ontologies

Keywords
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpurine nucleoside metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionpurine-nucleoside phosphorylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 237237Purine nucleoside phosphorylase DeoD-type HAMAP-Rule MF_01627
PRO_1000186231

Sequences

Sequence LengthMass (Da)Tools
A2RF09 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: 09666440A34732F9

FASTA23726,064
        10         20         30         40         50         60 
MSIHISAKKG DIADKILLPG DPLRAKFIAE NFLEDAVCFN EVRNMFGYTG TYKGHRVSVM 

        70         80         90        100        110        120 
GTGMGMPSIS IYARELIVDY GVKTLIRVGT AGAIDPEVHV RELVLAQAAA TNSNIIRNDF 

       130        140        150        160        170        180 
PEFDFPQIAD FGLLDKAYHI AREMGVTTHV GNVLSSDVFY TNMPERNMAL GKLGVKAIEM 

       190        200        210        220        230 
EAAALYYLAT QHHVKALGIM TISDNLNDPT EDTTAEERQT TFTDMMKIGL ETLIAND 

« Hide

References

[1]"Complete genome of acute rheumatic fever-associated serotype M5 Streptococcus pyogenes strain Manfredo."
Holden M.T.G., Scott A., Cherevach I., Chillingworth T., Churcher C., Cronin A., Dowd L., Feltwell T., Hamlin N., Holroyd S., Jagels K., Moule S., Mungall K., Quail M.A., Price C., Rabbinowitsch E., Sharp S., Skelton J. expand/collapse author list , Whitehead S., Barrell B.G., Kehoe M., Parkhill J.
J. Bacteriol. 189:1473-1477(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Manfredo.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM295007 Genomic DNA. Translation: CAM30435.1.
RefSeqYP_001128658.1. NC_009332.1.

3D structure databases

ProteinModelPortalA2RF09.
SMRA2RF09. Positions 1-232.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING160491.SpyM51109.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4963494.
KEGGspf:SpyM51109.
PATRIC19765400. VBIStrPyo41547_1152.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0813.
HOGENOMHOG000274896.
KOK03784.
OMAHMATSAT.
OrthoDBEOG6BKJC5.

Enzyme and pathway databases

BioCycSPYO160491:GJ8O-1165-MONOMER.

Family and domain databases

Gene3D3.40.50.1580. 1 hit.
HAMAPMF_01627. Pur_nucleosid_phosp.
InterProIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERPTHR21234. PTHR21234. 1 hit.
PfamPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMSSF53167. SSF53167. 1 hit.
TIGRFAMsTIGR00107. deoD. 1 hit.
PROSITEPS01232. PNP_UDP_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDEOD_STRPG
AccessionPrimary (citable) accession number: A2RF09
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 6, 2007
Last modified: May 14, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families