A2REL6 (A2REL6_STRPG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-amino-4-hydroxy-6-hydroxymethyldihydropteridi ne pyrophosphokinase EMBL CAM30291.1
EC=2.7.6.3 EMBL CAM30291.1

Gene names

Name:	folK EMBL CAM30291.1
Ordered Locus Names:	SpyM50964

Organism

Streptococcus pyogenes serotype M5 (strain Manfredo) [Complete proteome] [HAMAP]

Taxonomic identifier

160491 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus pyogenes › Streptococcus pyogenes serotype M5

Protein attributes

Sequence length	166 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Kinase EMBL CAM30291.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	folic acid-containing compound biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity Inferred from electronic annotation. Source: EC kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2REL6 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: 50BC8E155BF70A3A	FASTA	166	18,765
	10 20 30 40 50 60 MTIVYLSLGT NMGDRAAYLQ KALEALADLP QTRLLAQSSI YETTAWGKTG QADFLNMACQ 70 80 90 100 110 120 LDTQLTAADF LKETQAIEQS LGRVRHEKWG SRTIDIDILL FGEEVYDTKE LKVPHPYMTE 130 140 150 160 RAFVLIPLLE LQPGLKLPPN HKFLRDYLAA LDQSDITLFS AQQTEF

References

[1]

"Complete genome of acute rheumatic fever-associated serotype M5 Streptococcus pyogenes strain Manfredo." Holden M.T.G., Scott A., Cherevach I., Chillingworth T., Churcher C., Cronin A., Dowd L., Feltwell T., Hamlin N., Holroyd S., Jagels K., Moule S., Mungall K., Quail M.A., Price C., Rabbinowitsch E., Sharp S., Skelton J. , Whitehead S., Barrell B.G., Kehoe M., Parkhill J. J. Bacteriol. 189:1473-1477(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Manfredo.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM295007 Genomic DNA. Translation: CAM30291.1.
RefSeq	YP_001128521.1. NC_009332.1.
3D structure databases
ProteinModelPortal	A2REL6.
ModBase	Search...
Protein-protein interaction databases
STRING	160491.SpyM50964.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4964295.
KEGG	spf:SpyM50964.
PATRIC	19765096. VBIStrPyo41547_1003.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0801.
HOGENOM	HOG000217741.
KO	K00950.
OMA	DQDWFLN.
ProtClustDB	CLSK797492.
Family and domain databases
Gene3D	3.30.70.560. 1 hit.
InterPro	IPR000550. Hppk. [Graphical view]
Pfam	PF01288. HPPK. 1 hit. [Graphical view]
SUPFAM	SSF55083. Hppk. 1 hit.
TIGRFAMs	TIGR01498. folK. 1 hit.
PROSITE	PS00794. HPPK. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A2REL6_STRPG

Accession

Primary (citable) accession number: A2REL6

Entry history

Integrated into UniProtKB/TrEMBL:	March 6, 2007
Last sequence update:	March 6, 2007
Last modified:	May 1, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)