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A2RBA1

- RT106_ASPNC

UniProt

A2RBA1 - RT106_ASPNC

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Protein
Histone chaperone rtt106
Gene
rtt106, An18g06020
Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter By similarity.

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Histone chaperone rtt106
Gene namesi
Name:rtt106
ORF Names:An18g06020
OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)
Taxonomic identifieri425011 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006706: Chromosome 8L

Subcellular locationi

Nucleus By similarity. Chromosome By similarity

GO - Cellular componenti

  1. chromosome Source: UniProtKB-SubCell
  2. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Chromosome, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 458458Histone chaperone rtt106
PRO_0000320484Add
BLAST

Interactioni

Subunit structurei

Interacts with histones H3 and H4 By similarity.

Protein-protein interaction databases

STRINGi5061.CADANGAP00013971.

Structurei

3D structure databases

ProteinModelPortaliA2RBA1.

Family & Domainsi

Sequence similaritiesi

Belongs to the RTT106 family.

Phylogenomic databases

eggNOGiNOG78439.
HOGENOMiHOG000048523.
OrthoDBiEOG7TBCC0.

Family and domain databases

InterProiIPR013719. DUF1747.
[Graphical view]
PfamiPF08512. Rtt106. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2RBA1-1 [UniParc]FASTAAdd to Basket

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MAFATINSSV PSSIPAIEDA FAAEPALKKR VYDAIAHTPQ HGLLFEDIAK    50
YTSSLLARTA TAPVRPVEVV SDGPAMKKRK LQNGNATSAQ SSGDLKSDTS 100
LQFYMQDVSF AVPQRKKLTL EVTAGFLRAR NQTSKEVEFG VPLDNIQHVL 150
CLPVPEKNQR QFNFCIIPQY ADGVNSPPEG VAAPDAIVWT VNDGPPKAAF 200
SGNGQQLGTD NEETADKLVQ RILNDSLPRT KVVRPDEREF VSAMPEAHRK 250
GEKAFHVKAF RGSKEGYLFL LSTGILFGFK KPLVFFAFEN VDSISYTSVL 300
QRTFNLNVVA RPTSSEETQE FEFSMIDQAD FSGIDGYIKK HGLQDASLAE 350
ARRAKRYNVN GAKGEDEAAA NEEGAVEEES ELQKAQRELE DQEDEDEEDY 400
DPGSDSDSDG SGSSSEEDDD DDEEDDEGDM EEDDEEGDRN LVAEELGSEA 450
EDVPAEEL 458
Length:458
Mass (Da):50,310
Last modified:March 6, 2007 - v1
Checksum:i053AEFE3FBD85B59
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM270411 Genomic DNA. Translation: CAK43325.1.
RefSeqiXP_001399053.1. XM_001399016.1.

Genome annotation databases

EnsemblFungiiCADANGAT00014240; CADANGAP00013971; CADANGAG00014240.
GeneIDi4990168.
KEGGiang:ANI_1_806164.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM270411 Genomic DNA. Translation: CAK43325.1 .
RefSeqi XP_001399053.1. XM_001399016.1.

3D structure databases

ProteinModelPortali A2RBA1.
ModBasei Search...

Protein-protein interaction databases

STRINGi 5061.CADANGAP00013971.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADANGAT00014240 ; CADANGAP00013971 ; CADANGAG00014240 .
GeneIDi 4990168.
KEGGi ang:ANI_1_806164.

Phylogenomic databases

eggNOGi NOG78439.
HOGENOMi HOG000048523.
OrthoDBi EOG7TBCC0.

Family and domain databases

InterProi IPR013719. DUF1747.
[Graphical view ]
Pfami PF08512. Rtt106. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88."
    Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R., Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X., Contreras R., Cornell M.
    , Coutinho P.M., Danchin E.G.J., Debets A.J.M., Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M., d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J., Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W., van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E., Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J., Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H., Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.
    Nat. Biotechnol. 25:221-231(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CBS 513.88 / FGSC A1513.

Entry informationi

Entry nameiRT106_ASPNC
AccessioniPrimary (citable) accession number: A2RBA1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: March 6, 2007
Last modified: February 19, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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