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A2RBA1 (RT106_ASPNC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Histone chaperone rtt106
Gene names
Name:rtt106
ORF Names:An18g06020
OrganismAspergillus niger (strain CBS 513.88 / FGSC A1513) [Complete proteome]
Taxonomic identifier425011 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length458 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter By similarity.

Subunit structure

Interacts with histones H3 and H4 By similarity.

Subcellular location

Nucleus By similarity. Chromosome By similarity.

Sequence similarities

Belongs to the RTT106 family.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentChromosome
Nucleus
   LigandDNA-binding
   Molecular functionChaperone
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processregulation of transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentchromosome

Inferred from electronic annotation. Source: UniProtKB-SubCell

nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 458458Histone chaperone rtt106
PRO_0000320484

Sequences

Sequence LengthMass (Da)Tools
A2RBA1 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: 053AEFE3FBD85B59

FASTA45850,310
        10         20         30         40         50         60 
MAFATINSSV PSSIPAIEDA FAAEPALKKR VYDAIAHTPQ HGLLFEDIAK YTSSLLARTA 

        70         80         90        100        110        120 
TAPVRPVEVV SDGPAMKKRK LQNGNATSAQ SSGDLKSDTS LQFYMQDVSF AVPQRKKLTL 

       130        140        150        160        170        180 
EVTAGFLRAR NQTSKEVEFG VPLDNIQHVL CLPVPEKNQR QFNFCIIPQY ADGVNSPPEG 

       190        200        210        220        230        240 
VAAPDAIVWT VNDGPPKAAF SGNGQQLGTD NEETADKLVQ RILNDSLPRT KVVRPDEREF 

       250        260        270        280        290        300 
VSAMPEAHRK GEKAFHVKAF RGSKEGYLFL LSTGILFGFK KPLVFFAFEN VDSISYTSVL 

       310        320        330        340        350        360 
QRTFNLNVVA RPTSSEETQE FEFSMIDQAD FSGIDGYIKK HGLQDASLAE ARRAKRYNVN 

       370        380        390        400        410        420 
GAKGEDEAAA NEEGAVEEES ELQKAQRELE DQEDEDEEDY DPGSDSDSDG SGSSSEEDDD 

       430        440        450 
DDEEDDEGDM EEDDEEGDRN LVAEELGSEA EDVPAEEL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM270411 Genomic DNA. Translation: CAK43325.1.
RefSeqXP_001399053.1. XM_001399016.1.

3D structure databases

ProteinModelPortalA2RBA1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5061.CADANGAP00013971.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADANGAT00014240; CADANGAP00013971; CADANGAG00014240.
GeneID4990168.
KEGGang:ANI_1_806164.

Phylogenomic databases

eggNOGNOG78439.
HOGENOMHOG000048523.
OrthoDBEOG7TBCC0.

Family and domain databases

InterProIPR013719. DUF1747.
[Graphical view]
PfamPF08512. Rtt106. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRT106_ASPNC
AccessionPrimary (citable) accession number: A2RBA1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: March 6, 2007
Last modified: February 19, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families