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Protein

Histone chaperone rtt106

Gene

rtt106

Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone chaperone rtt106
Gene namesi
Name:rtt106
ORF Names:An18g06020
OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)
Taxonomic identifieri425011 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006706 Componenti: Chromosome 8L

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003204841 – 458Histone chaperone rtt106Add BLAST458

Proteomic databases

PaxDbiA2RBA1

Interactioni

Subunit structurei

Interacts with histones H3 and H4.By similarity

Structurei

3D structure databases

ProteinModelPortaliA2RBA1
SMRiA2RBA1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RTT106 family.Curated

Phylogenomic databases

HOGENOMiHOG000048523
OrthoDBiEOG092C40DW

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR013719 DUF1747
IPR011993 PH-like_dom_sf
PfamiView protein in Pfam
PF08512 Rtt106, 1 hit
SMARTiView protein in SMART
SM01287 Rtt106, 1 hit

Sequencei

Sequence statusi: Complete.

A2RBA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFATINSSV PSSIPAIEDA FAAEPALKKR VYDAIAHTPQ HGLLFEDIAK
60 70 80 90 100
YTSSLLARTA TAPVRPVEVV SDGPAMKKRK LQNGNATSAQ SSGDLKSDTS
110 120 130 140 150
LQFYMQDVSF AVPQRKKLTL EVTAGFLRAR NQTSKEVEFG VPLDNIQHVL
160 170 180 190 200
CLPVPEKNQR QFNFCIIPQY ADGVNSPPEG VAAPDAIVWT VNDGPPKAAF
210 220 230 240 250
SGNGQQLGTD NEETADKLVQ RILNDSLPRT KVVRPDEREF VSAMPEAHRK
260 270 280 290 300
GEKAFHVKAF RGSKEGYLFL LSTGILFGFK KPLVFFAFEN VDSISYTSVL
310 320 330 340 350
QRTFNLNVVA RPTSSEETQE FEFSMIDQAD FSGIDGYIKK HGLQDASLAE
360 370 380 390 400
ARRAKRYNVN GAKGEDEAAA NEEGAVEEES ELQKAQRELE DQEDEDEEDY
410 420 430 440 450
DPGSDSDSDG SGSSSEEDDD DDEEDDEGDM EEDDEEGDRN LVAEELGSEA

EDVPAEEL
Length:458
Mass (Da):50,310
Last modified:March 6, 2007 - v1
Checksum:i053AEFE3FBD85B59
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM270411 Genomic DNA Translation: CAK43325.1
RefSeqiXP_001399053.1, XM_001399016.1

Genome annotation databases

EnsemblFungiiCAK43325; CAK43325; An18g06020
GeneIDi4990168
KEGGiang:ANI_1_806164

Similar proteinsi

Entry informationi

Entry nameiRT106_ASPNC
AccessioniPrimary (citable) accession number: A2RBA1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: March 6, 2007
Last modified: March 28, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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