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A2RBA1

- RT106_ASPNC

UniProt

A2RBA1 - RT106_ASPNC

Protein

Histone chaperone rtt106

Gene

rtt106

Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (06 Mar 2007)
      Previous versions | rss
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    Functioni

    Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter By similarity.By similarity

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chaperone

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histone chaperone rtt106
    Gene namesi
    Name:rtt106
    ORF Names:An18g06020
    OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)
    Taxonomic identifieri425011 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000006706: Chromosome 8L

    Subcellular locationi

    Nucleus By similarity. Chromosome By similarity

    GO - Cellular componenti

    1. chromosome Source: UniProtKB-SubCell
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Chromosome, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 458458Histone chaperone rtt106PRO_0000320484Add
    BLAST

    Interactioni

    Subunit structurei

    Interacts with histones H3 and H4.By similarity

    Protein-protein interaction databases

    STRINGi5061.CADANGAP00013971.

    Structurei

    3D structure databases

    ProteinModelPortaliA2RBA1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RTT106 family.Curated

    Phylogenomic databases

    eggNOGiNOG78439.
    HOGENOMiHOG000048523.
    OrthoDBiEOG7TBCC0.

    Family and domain databases

    InterProiIPR013719. DUF1747.
    [Graphical view]
    PfamiPF08512. Rtt106. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A2RBA1-1 [UniParc]FASTAAdd to Basket

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    MAFATINSSV PSSIPAIEDA FAAEPALKKR VYDAIAHTPQ HGLLFEDIAK    50
    YTSSLLARTA TAPVRPVEVV SDGPAMKKRK LQNGNATSAQ SSGDLKSDTS 100
    LQFYMQDVSF AVPQRKKLTL EVTAGFLRAR NQTSKEVEFG VPLDNIQHVL 150
    CLPVPEKNQR QFNFCIIPQY ADGVNSPPEG VAAPDAIVWT VNDGPPKAAF 200
    SGNGQQLGTD NEETADKLVQ RILNDSLPRT KVVRPDEREF VSAMPEAHRK 250
    GEKAFHVKAF RGSKEGYLFL LSTGILFGFK KPLVFFAFEN VDSISYTSVL 300
    QRTFNLNVVA RPTSSEETQE FEFSMIDQAD FSGIDGYIKK HGLQDASLAE 350
    ARRAKRYNVN GAKGEDEAAA NEEGAVEEES ELQKAQRELE DQEDEDEEDY 400
    DPGSDSDSDG SGSSSEEDDD DDEEDDEGDM EEDDEEGDRN LVAEELGSEA 450
    EDVPAEEL 458
    Length:458
    Mass (Da):50,310
    Last modified:March 6, 2007 - v1
    Checksum:i053AEFE3FBD85B59
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM270411 Genomic DNA. Translation: CAK43325.1.
    RefSeqiXP_001399053.1. XM_001399016.1.

    Genome annotation databases

    EnsemblFungiiCADANGAT00014240; CADANGAP00013971; CADANGAG00014240.
    GeneIDi4990168.
    KEGGiang:ANI_1_806164.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM270411 Genomic DNA. Translation: CAK43325.1 .
    RefSeqi XP_001399053.1. XM_001399016.1.

    3D structure databases

    ProteinModelPortali A2RBA1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5061.CADANGAP00013971.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADANGAT00014240 ; CADANGAP00013971 ; CADANGAG00014240 .
    GeneIDi 4990168.
    KEGGi ang:ANI_1_806164.

    Phylogenomic databases

    eggNOGi NOG78439.
    HOGENOMi HOG000048523.
    OrthoDBi EOG7TBCC0.

    Family and domain databases

    InterProi IPR013719. DUF1747.
    [Graphical view ]
    Pfami PF08512. Rtt106. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88."
      Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R., Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X., Contreras R., Cornell M.
      , Coutinho P.M., Danchin E.G.J., Debets A.J.M., Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M., d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J., Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W., van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E., Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J., Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H., Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.
      Nat. Biotechnol. 25:221-231(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CBS 513.88 / FGSC A1513.

    Entry informationi

    Entry nameiRT106_ASPNC
    AccessioniPrimary (citable) accession number: A2RBA1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 26, 2008
    Last sequence update: March 6, 2007
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3