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A2RAL4 (BGLA_ASPNC) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable beta-glucosidase A

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase A
Cellobiase A
Gentiobiase A
Gene names
Name:bglA
Synonyms:bgl1
ORF Names:An18g03570
OrganismAspergillus niger (strain CBS 513.88 / FGSC A1513) [Complete proteome]
Taxonomic identifier425011 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length860 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose By similarity.

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 860841Probable beta-glucosidase A
PRO_5000221323

Sites

Active site2801 By similarity

Amino acid modifications

Glycosylation611N-linked (GlcNAc...) Potential
Glycosylation2111N-linked (GlcNAc...) Potential
Glycosylation2521N-linked (GlcNAc...) Potential
Glycosylation3151N-linked (GlcNAc...) Potential
Glycosylation3221N-linked (GlcNAc...) Potential
Glycosylation3541N-linked (GlcNAc...) Potential
Glycosylation3871N-linked (GlcNAc...) Potential
Glycosylation4421N-linked (GlcNAc...) Potential
Glycosylation5231N-linked (GlcNAc...) Potential
Glycosylation5421N-linked (GlcNAc...) Potential
Glycosylation5641N-linked (GlcNAc...) Potential
Glycosylation6581N-linked (GlcNAc...) Potential
Glycosylation6901N-linked (GlcNAc...) Potential
Glycosylation7121N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A2RAL4 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: 087215D2E1F89643

FASTA86093,229
        10         20         30         40         50         60 
MRFTSIEAVA LTAVSLASAD ELAYSPPYYP SPWANGQGDW AEAYQRAVDI VSQMTLAEKV 

        70         80         90        100        110        120 
NLTTGTGWEL ELCVGQTGGV PRLGIPGMCA QDSPLGVRDS DYNSAFPAGV NVAATWDKNL 

       130        140        150        160        170        180 
AYLRGQAMGQ EFSDKGADIQ LGPAAGPLGR SPDGGRNWEG FSPDPALSGV LFAETIKGIQ 

       190        200        210        220        230        240 
DAGVVATAKH YIAYEQEHFR QAPEAQGYGF NITESGSANL DDKTMHELYL WPFADAIRAG 

       250        260        270        280        290        300 
AGAVMCSYNQ INNSYGCQNS YTLNKLLKAE LGFQGFVMSD WAAHHAGVSG ALAGLDMSMP 

       310        320        330        340        350        360 
GDVDYDSGTS YWGTNLTISV LNGTVPQWRV DDMAVRIMAA YYKVGRDRLW TPPNFSSWTR 

       370        380        390        400        410        420 
DEYGFKYYYV SEGPYEKVNQ FVNVQRNHSE LIRRIGADST VLLKNDGALP LTGKERLVAL 

       430        440        450        460        470        480 
IGEDAGSNPY GANGCSDRGC DNGTLAMGWG SGTANFPYLV TPEQAISNEV LKNKNGVFTA 

       490        500        510        520        530        540 
TDNWAIDQIE ALAKTASVSL VFVNADSGEG YINVDGNLGD RRNLTLWRNG DNVIKAAASN 

       550        560        570        580        590        600 
CNNTIVIIHS VGPVLVNEWY DNPNVTAILW GGLPGQESGN SLADVLYGRV NPGAKSPFTW 

       610        620        630        640        650        660 
GKTREAYQDY LYTEPNNGNG APQEDFVEGV FIDYRGFDKR NETPIYEFGY GLSYTTFNYS 

       670        680        690        700        710        720 
NLQVEVLSAP AYEPASGETE AAPTFGEVGN ASDYLYPDGL QRITKFIYPW LNSTDLEASS 

       730        740        750        760        770        780 
GDASYGQDAS DYLPEGATDG SAQPILPAGG GAGGNPRLYD ELIRVSVTIK NTGKVAGDEV 

       790        800        810        820        830        840 
PQLYVSLGGP NEPKIVLRQF ERITLQPSKE TQWSTTLTRR DLANWNVETQ DWEITSYPKM 

       850        860 
VFAGSSSRKL PLRASLPTVH 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM270402 Genomic DNA. Translation: CAK48740.1.
RefSeqXP_001398816.1. XM_001398779.2.

3D structure databases

ProteinModelPortalA2RAL4.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH3. Glycoside Hydrolase Family 3.

Proteomic databases

PRIDEA2RAL4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADANGAT00013994; CADANGAP00013734; CADANGAG00013994.
GeneID4989921.
KEGGang:ANI_1_456164.

Phylogenomic databases

HOGENOMHOG000031215.
KOK05349.
OrthoDBEOG7HMS8F.

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
PROSITEPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBGLA_ASPNC
AccessionPrimary (citable) accession number: A2RAL4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: March 6, 2007
Last modified: November 13, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries