Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A2R797

- AFCA_ASPNC

UniProt

A2R797 - AFCA_ASPNC

Protein

Probable alpha-fucosidase A

Gene

afcA

Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (06 Mar 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Alpha-fucosidase involved in degradation of fucosylated xyloglucans. Hydrolyzes alpha-1,2-linked fucose By similarity.By similarity

    Catalytic activityi

    An alpha-L-fucoside + H2O = L-fucose + an alcohol.

    GO - Molecular functioni

    1. alpha-L-fucosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. polysaccharide catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Polysaccharide degradation

    Protein family/group databases

    CAZyiGH95. Glycoside Hydrolase Family 95.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable alpha-fucosidase A (EC:3.2.1.51)
    Alternative name(s):
    Alpha-L-fucoside fucohydrolase A
    Gene namesi
    Name:afcA
    ORF Names:An16g02760
    OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)
    Taxonomic identifieri425011 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000006706: Chromosome 5R

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2020Sequence AnalysisAdd
    BLAST
    Chaini21 – 793773Probable alpha-fucosidase APRO_5000221152Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi30 – 301N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi83 – 831N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi100 – 1001N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi104 – 1041N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi123 – 1231N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi179 – 1791N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi199 – 1991N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi234 – 2341N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi323 – 3231N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi597 – 5971N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi622 – 6221N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi660 – 6601N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi757 – 7571N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi5061.CADANGAP00012507.

    Structurei

    3D structure databases

    ProteinModelPortaliA2R797.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 95 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG04067.
    HOGENOMiHOG000235039.
    OrthoDBiEOG77HDP8.

    Family and domain databases

    Gene3Di2.70.98.50. 1 hit.
    InterProiIPR008928. 6-hairpin_glycosidase-like.
    IPR016518. Alpha-L-fucosidase.
    IPR027414. GH_fam_N_dom.
    [Graphical view]
    PfamiPF14498. Glyco_hyd_65N_2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF007663. UCP007663. 1 hit.
    SUPFAMiSSF48208. SSF48208. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    A2R797-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLISGSSAAL CALALPFAAA KSLWSDSPGN YSSFITTAFP LGNGRLGAMP    50
    IGSYDKEIVN LNVDSLWRGG PFESPTYSGG NPNVSKAGAL PGIREWIFQN 100
    GTGNVSALLG EYPYYGSYQV LANLTIDMGE LSDIDGYRRN LDLDSAVYSD 150
    HFSTGETYIE REAFCSYPDN VCVYRLSSNS SLPEITFGLE NQLTSPAPNV 200
    SCHGNSISLY GQTYPVIGMI YNARVTVVVP GSSNTTDLCS SSTVKVPEGE 250
    KEVFLVFAAD TNYEASNGNS KASFSFKGEN PYMKVLQTAT NAAKKSYSAL 300
    KSSHVKDYQG VFNKFTLTLP DPNGSADRPT TELLSSYSQP GDPYVENLLF 350
    DYGRYLFISS SRPGSLPPNL QGLWTESYSP AWSGDYHANI NLQMNHWAVD 400
    QTGLGELTEP LWTYMAETWM PRGAETAELL YGTSEGWVTH DEMNTFGHTA 450
    MKDVAQWADY PATNAWMSHH VWDHFDYSQD SAWYRETGYP ILKGAAQFWL 500
    SQLVKDEYFK DGTLVVNPCN SPEHGPTLTP QTFGCTHYQQ LIWELFDHVL 550
    QGWTASGDDD TSFKNAITSK FSTLDPGIHI GSWGQIQEWK LDIDVKNDTH 600
    RHLSNLYGWY PGYIISSVHG SNKTITDAVE TTLYSRGTGV EDSNTGWAKV 650
    WRSACWALLN VTDEAYSELS LAIQDNFAEN GFDMYSGSPP FQIDANFGLV 700
    GAMVQMLIRD SDRSSADASA GKTQDVLLGP AIPAAWGGGS VGGLRLRGGG 750
    VVSFSWNDSG VVDSCKADLS ARGSDVSQVK FYVAGGRAID CSS 793
    Length:793
    Mass (Da):86,565
    Last modified:March 6, 2007 - v1
    Checksum:i4F510561054875E2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM270362 Genomic DNA. Translation: CAK48586.1.

    Genome annotation databases

    EnsemblFungiiCADANGAT00012747; CADANGAP00012507; CADANGAG00012747.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM270362 Genomic DNA. Translation: CAK48586.1 .

    3D structure databases

    ProteinModelPortali A2R797.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5061.CADANGAP00012507.

    Protein family/group databases

    CAZyi GH95. Glycoside Hydrolase Family 95.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADANGAT00012747 ; CADANGAP00012507 ; CADANGAG00012747 .

    Phylogenomic databases

    eggNOGi NOG04067.
    HOGENOMi HOG000235039.
    OrthoDBi EOG77HDP8.

    Family and domain databases

    Gene3Di 2.70.98.50. 1 hit.
    InterProi IPR008928. 6-hairpin_glycosidase-like.
    IPR016518. Alpha-L-fucosidase.
    IPR027414. GH_fam_N_dom.
    [Graphical view ]
    Pfami PF14498. Glyco_hyd_65N_2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF007663. UCP007663. 1 hit.
    SUPFAMi SSF48208. SSF48208. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88."
      Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R., Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X., Contreras R., Cornell M.
      , Coutinho P.M., Danchin E.G.J., Debets A.J.M., Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M., d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J., Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W., van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E., Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J., Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H., Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.
      Nat. Biotechnol. 25:221-231(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CBS 513.88 / FGSC A1513.

    Entry informationi

    Entry nameiAFCA_ASPNC
    AccessioniPrimary (citable) accession number: A2R797
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 15, 2010
    Last sequence update: March 6, 2007
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3