SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A2R797

- AFCA_ASPNC

UniProt

A2R797 - AFCA_ASPNC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable alpha-fucosidase A

Gene
afcA, An16g02760
Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Alpha-fucosidase involved in degradation of fucosylated xyloglucans. Hydrolyzes alpha-1,2-linked fucose By similarity.

Catalytic activityi

An alpha-L-fucoside + H2O = L-fucose + an alcohol.

GO - Molecular functioni

  1. alpha-L-fucosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. polysaccharide catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Polysaccharide degradation

Protein family/group databases

CAZyiGH95. Glycoside Hydrolase Family 95.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable alpha-fucosidase A (EC:3.2.1.51)
Alternative name(s):
Alpha-L-fucoside fucohydrolase A
Gene namesi
Name:afcA
ORF Names:An16g02760
OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)
Taxonomic identifieri425011 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006706: Chromosome 5R

Subcellular locationi

Secreted By similarity

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020 Reviewed predictionAdd
BLAST
Chaini21 – 793773Probable alpha-fucosidase APRO_5000221152Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi30 – 301N-linked (GlcNAc...) Reviewed prediction
Glycosylationi83 – 831N-linked (GlcNAc...) Reviewed prediction
Glycosylationi100 – 1001N-linked (GlcNAc...) Reviewed prediction
Glycosylationi104 – 1041N-linked (GlcNAc...) Reviewed prediction
Glycosylationi123 – 1231N-linked (GlcNAc...) Reviewed prediction
Glycosylationi179 – 1791N-linked (GlcNAc...) Reviewed prediction
Glycosylationi199 – 1991N-linked (GlcNAc...) Reviewed prediction
Glycosylationi234 – 2341N-linked (GlcNAc...) Reviewed prediction
Glycosylationi323 – 3231N-linked (GlcNAc...) Reviewed prediction
Glycosylationi597 – 5971N-linked (GlcNAc...) Reviewed prediction
Glycosylationi622 – 6221N-linked (GlcNAc...) Reviewed prediction
Glycosylationi660 – 6601N-linked (GlcNAc...) Reviewed prediction
Glycosylationi757 – 7571N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi5061.CADANGAP00012507.

Structurei

3D structure databases

ProteinModelPortaliA2R797.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG04067.
HOGENOMiHOG000235039.
OrthoDBiEOG77HDP8.

Family and domain databases

Gene3Di2.70.98.50. 1 hit.
InterProiIPR008928. 6-hairpin_glycosidase-like.
IPR016518. Alpha-L-fucosidase.
IPR027414. GH_fam_N_dom.
[Graphical view]
PfamiPF14498. Glyco_hyd_65N_2. 1 hit.
[Graphical view]
PIRSFiPIRSF007663. UCP007663. 1 hit.
SUPFAMiSSF48208. SSF48208. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A2R797-1 [UniParc]FASTAAdd to Basket

« Hide

MLISGSSAAL CALALPFAAA KSLWSDSPGN YSSFITTAFP LGNGRLGAMP    50
IGSYDKEIVN LNVDSLWRGG PFESPTYSGG NPNVSKAGAL PGIREWIFQN 100
GTGNVSALLG EYPYYGSYQV LANLTIDMGE LSDIDGYRRN LDLDSAVYSD 150
HFSTGETYIE REAFCSYPDN VCVYRLSSNS SLPEITFGLE NQLTSPAPNV 200
SCHGNSISLY GQTYPVIGMI YNARVTVVVP GSSNTTDLCS SSTVKVPEGE 250
KEVFLVFAAD TNYEASNGNS KASFSFKGEN PYMKVLQTAT NAAKKSYSAL 300
KSSHVKDYQG VFNKFTLTLP DPNGSADRPT TELLSSYSQP GDPYVENLLF 350
DYGRYLFISS SRPGSLPPNL QGLWTESYSP AWSGDYHANI NLQMNHWAVD 400
QTGLGELTEP LWTYMAETWM PRGAETAELL YGTSEGWVTH DEMNTFGHTA 450
MKDVAQWADY PATNAWMSHH VWDHFDYSQD SAWYRETGYP ILKGAAQFWL 500
SQLVKDEYFK DGTLVVNPCN SPEHGPTLTP QTFGCTHYQQ LIWELFDHVL 550
QGWTASGDDD TSFKNAITSK FSTLDPGIHI GSWGQIQEWK LDIDVKNDTH 600
RHLSNLYGWY PGYIISSVHG SNKTITDAVE TTLYSRGTGV EDSNTGWAKV 650
WRSACWALLN VTDEAYSELS LAIQDNFAEN GFDMYSGSPP FQIDANFGLV 700
GAMVQMLIRD SDRSSADASA GKTQDVLLGP AIPAAWGGGS VGGLRLRGGG 750
VVSFSWNDSG VVDSCKADLS ARGSDVSQVK FYVAGGRAID CSS 793
Length:793
Mass (Da):86,565
Last modified:March 6, 2007 - v1
Checksum:i4F510561054875E2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM270362 Genomic DNA. Translation: CAK48586.1.

Genome annotation databases

EnsemblFungiiCADANGAT00012747; CADANGAP00012507; CADANGAG00012747.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM270362 Genomic DNA. Translation: CAK48586.1 .

3D structure databases

ProteinModelPortali A2R797.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5061.CADANGAP00012507.

Protein family/group databases

CAZyi GH95. Glycoside Hydrolase Family 95.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADANGAT00012747 ; CADANGAP00012507 ; CADANGAG00012747 .

Phylogenomic databases

eggNOGi NOG04067.
HOGENOMi HOG000235039.
OrthoDBi EOG77HDP8.

Family and domain databases

Gene3Di 2.70.98.50. 1 hit.
InterProi IPR008928. 6-hairpin_glycosidase-like.
IPR016518. Alpha-L-fucosidase.
IPR027414. GH_fam_N_dom.
[Graphical view ]
Pfami PF14498. Glyco_hyd_65N_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF007663. UCP007663. 1 hit.
SUPFAMi SSF48208. SSF48208. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88."
    Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R., Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X., Contreras R., Cornell M.
    , Coutinho P.M., Danchin E.G.J., Debets A.J.M., Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M., d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J., Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W., van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E., Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J., Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H., Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.
    Nat. Biotechnol. 25:221-231(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CBS 513.88 / FGSC A1513.

Entry informationi

Entry nameiAFCA_ASPNC
AccessioniPrimary (citable) accession number: A2R797
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: March 6, 2007
Last modified: April 16, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi