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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

An15g07390

Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei46NADUniRule annotation1
Binding sitei116NADUniRule annotation1
Binding sitei139SubstrateUniRule annotation1
Binding sitei172NAD; via amide nitrogenUniRule annotation1
Active sitei265Proton acceptorUniRule annotation1
Binding sitei331NADUniRule annotation1
Binding sitei358NAD; via amide nitrogenUniRule annotation1
Binding sitei360NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi14 – 19NADUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
ORF Names:An15g07390Imported
OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)Imported
Taxonomic identifieri425011 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006706 Componenti: Chromosome 3R

Subcellular locationi

PTM / Processingi

Proteomic databases

PaxDbiA2R6C3

Interactioni

Protein-protein interaction databases

STRINGi5061.CADANGAP00012183

Structurei

3D structure databases

ProteinModelPortaliA2R6C3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 189NAD_Gly3P_dh_NInterPro annotationAdd BLAST181
Domaini254 – 399NAD_Gly3P_dh_CInterPro annotationAdd BLAST146

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni331 – 332Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000246855
KOiK00006
OrthoDBiEOG092C3ZQP

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR006168 G3P_DH_NAD-dep
IPR006109 G3P_DH_NAD-dep_C
IPR011128 G3P_DH_NAD-dep_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF07479 NAD_Gly3P_dh_C, 1 hit
PF01210 NAD_Gly3P_dh_N, 1 hit
PIRSFiPIRSF000114 Glycerol-3-P_dh, 1 hit
PRINTSiPR00077 GPDHDRGNASE
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 2 hits
PROSITEiView protein in PROSITE
PS00957 NAD_G3PDH, 1 hit

Sequencei

Sequence statusi: Complete.

A2R6C3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHEHTRKHKV AVVGSGNWGS TISKIVAENA REHSDLFEPE VRMWVFEEEI
60 70 80 90 100
EIPESSKHHS KLGGQKHKLT EVINGVHENV KYLPDIALPE NVVADPDLKS
110 120 130 140 150
AVKDATLLVF NLPHQFIGKT LDGVVGHHLP YARGISCIKG VDVSDGTVTL
160 170 180 190 200
HSELIMERLG IYCGALSGAN IAPEVAAEKF CETTIGYDTP PMDVEERDGS
210 220 230 240 250
PKENLIKIDE QRQHKTKPTH VKLHPVPKDL PPVDAELWET LFARPYFHVN
260 270 280 290 300
HVRDVAGVAL GGALKNIVAL ASGFVAGKGW GENAKAAIMR VGILEMIKFG
310 320 330 340 350
RTWFPKSVDE RTFTEESAGL ADVISSCSGG RNFRSACHAV EQGVSVNEIE
360 370 380 390 400
QKELNGQKLQ GTSTAYAVYD FLSKHDQLKE FPLFVAVHDI LEGKSTVDDL
410
PALLDGKKKK NKSA
Length:414
Mass (Da):45,449
Last modified:March 6, 2007 - v1
Checksum:i5E64C900A03584EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM270351 Genomic DNA Translation: CAK48573.1
RefSeqiXP_001397265.1, XM_001397228.1

Genome annotation databases

EnsemblFungiiCAK48573; CAK48573; An15g07390
GeneIDi4988340
KEGGiang:ANI_1_1768134

Similar proteinsi

Entry informationi

Entry nameiA2R6C3_ASPNC
AccessioniPrimary (citable) accession number: A2R6C3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: May 23, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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